Results 251 to 260 of about 1,682,968 (306)

Development of a TaqMan-Based Duplex Real-Time Quantitative RT-PCR for Detection and Differentiation of Muscovy Duck Reovirus and Novel Duck Reovirus. [PDF]

Pathogens
Liu L, Fu J, Lin M, Wang A, Wu S, Liu C.
europepmc   +1 more source

G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis

Advanced Science, EarlyView.
Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang, Cancan Yao, Yan Chen, Ke Cai, Zhouping Lu, Boxuan Wu, Kun Yu, Yan Shi, Jianyuan Zhao, Xiangyu Zhou   +9 more
wiley   +1 more source

O‐GlcNAcylated TAP1 Impairs Antigen Presentation and Promotes Immune Evasion in Bladder Cancer

Advanced Science, EarlyView.
This article unveils a critical mechanism of immune evasion in bladder cancer, which the O‐GlcNAc modification of TAP1 disrupts antigen presentation. This modification triggers HLA‐A degradation, shielding tumor cells from CD8+ T cell attack. The findings highlight targeting this pathway as a promising therapeutic avenue to sensitize tumors to ...
Jinpeng Wu, Xueting Ren, Zhen Zhai, Lu Wang, Liang Liang, Zengqi Tan, Jiazhen Zhao, Yuxuan Han, Yuhan Li, Feng Guan, Xiang Li   +10 more
wiley   +1 more source

Development and validation of a sample-to-result real time multiplex RT-PCR test for human African trypanosomiasis and arboviral febrile illnesses in the Democratic Republic of the Congo. [PDF]

BMC Infect Dis
Hauner A, Lusala SM, Rogé S, Van Reet N, Cnops L, Da Luz RI, Van Esbroeck M, Kapandji M, Kuamfumu MM, Kiabanzawoko O, Phanzu DM, Verlé P, Ahuka-Mundeke S, Ariën KK.   +13 more
europepmc   +1 more source

Direct real-time RT-PCR for the detection of dengue virus from patient serum in Lao PDR. [PDF]

PLoS One
Phimolsannousith V, Vongsouvath M, Kiedsathid P, Vongsouvath M, Ashley EA, Dubot-Pérès A.   +5 more
europepmc   +1 more source

Evaluating the potential of GSPT2 and CIRBP as biomarkers in endometrial cancer: Multicenter RT-PCR and IHC study. [PDF]

Medicine (Baltimore)
Cai Y, Wang M, He Y, Wu YM, Wang J, Xing L, Han Q, He YH.   +7 more
europepmc   +1 more source

Prolonged SARS-CoV-2 RNA detection by RT-PCR: variability in cycle threshold values over time. [PDF]

Microbiol Spectr
Muñoz-Gallego I, Rubio A, Maseda M, Carnicero P, Folgueira L.   +4 more
europepmc   +1 more source

Development of multiplex RT-PCR assays containing an internal amplification control for the detection of dicistro-, iflaviruses and CBPV in honey bees. Part 1 - assays design and optimization. [PDF]

Vet Res Commun
Zdańska D, Rzeżutka A, Pohorecka K.
europepmc   +1 more source

Jejunum FABP6 expression and potential mechanism response to Salmonella Pullorum inoculation revealed by proteomic profiling and RT-PCR in Chinese Taihe black-bone silky fowls. [PDF]

Poult Sci
Ye M, Zhang L, Yuan L, Xiang J, Liao Q, Long W, Dong Y, Yu X, Ai Q, Qiu S, Zhang D.   +10 more
europepmc   +1 more source