Nlrp6 promotes recovery after peripheral nerve injury independently of inflammasomes [PDF]
Background: NOD-like receptors (Nlrs) are key regulators of immune responses during infection and autoimmunity. A subset of Nlrs assembles inflammasomes, molecular platforms that are activated in response to endogenous danger and microbial ligands and ...
De Winter, Vicky +6 more
core +2 more sources
A tissue-based approach to selection of reference genes for quantitative real-time PCR in a sheep osteoporosis model [PDF]
Background: In order to better understand the multifactorial nature of osteoporosis, animal models are utilized and compared to healthy controls. Female sheep are well established as a model for osteoporosis induced by ovariectomy, calcium and vitamin D ...
EL Khassawna, Thaqif +6 more
core +2 more sources
Transcriptional cellular responses in midgut tissue of Aedes aegypti larvae following intoxication with Cry11Aa toxin from Bacillus thuringiensis. [PDF]
BackgroundAlthough much is known about the mechanism of action of Bacillus thuringiensis Cry toxins, the target tissue cellular responses to toxin activity is less understood.
Bravo, Alejandra +4 more
core +1 more source
Gene Expression Profile Changes After Short-activating RNA-mediated Induction of Endogenous Pluripotency Factors in Human Mesenchymal Stem Cells [PDF]
It is now recognized that small noncoding RNA sequences have the ability to mediate transcriptional activation of specific target genes in human cells.
Alluin, J +7 more
core +4 more sources
HAGE, a cancer/testis antigen expressed at the protein level in a variety of cancers [PDF]
The search for novel tumour antigens that are either uniquely expressed or over-expressed in a wide variety of tumours is still ongoing. Because of their expression in a broad spectrum of cancers and limited expression in normal tissues, cancer/testis ...
Badoual, C +6 more
core
Rapid, sensitive and effective diagnostic tools for foot-and-mouth disease virus in Africa
Speed is paramount in the diagnosis of highly infectious diseases, such as foot-and-mouth disease (FMD), as well as for emerging diseases; however, simplicity is required if a test is to be deployed in the field.
Christopher J. Kasanga +11 more
doaj +1 more source
Procedure used for RT-qPCR in the WetLab-2 study as well as procedure for preparation of lyophilized ...
openaire +1 more source
Background The accurate quantification of Plasmodium falciparum parasite numbers by PCR is an important tool for monitoring growth kinetics in subjects infected and subsequently treated with anti-malarial agents.
Trenholme Katharine +8 more
doaj +1 more source
New Method for Lawsonia intracelullaris Quantification Based on Optical Density by Spectrophotometry
Studies investigating the pathogenesis of Lawsonia intracellularis often require bacterial quantification in suspension. However, due to the organism’s fastidious growth requirements—being both intracellular and microaerophilic—traditional quantification
Mirtha E. Suarez-Duarte +8 more
doaj +1 more source

