Results 111 to 120 of about 952,520 (310)
Primer and TaqMan probe sequences used for (RT-) qPCR and IC-RT-PCR assays in this study.
, 2023 Primer and TaqMan probe sequences used for (RT-) qPCR and IC-RT-PCR assays in this study.
Akihiko Hata (4610323) +4 more
core +1 more source
Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source
Guangxi Yike Daxue xuebaoObjective To evaluate the diagnostic value of reverse transcription-quantitative polymerase chain reaction (RT-qPCR) detection of skin pus specimens in HIV-negative patients with talaromycosis marneffei (TSM).
Lan HUANG +7 more
doaj +1 more source
RT-qPCR-performance is independent from storage time in PET blocks stored at 4°C.
, 2018 Human FFPE (A and C) and PFPE (B and D) tissue (case #1, soft tissue) were stored at 4°C (A and B) or at room temperature (C and D) for up to 6 years prior to RNA extraction.
Nadine Dettmann (5728910) +4 more
core +1 more source
Molecular Oncology, EarlyView.LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David +12 more
wiley +1 more source
Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
Molecular Oncology, EarlyView.LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source
Detection of Chikungunya Virus RNA in Oral Fluid and Urine: An Alternative Approach to Diagnosis?
VirusesTo evaluate whether oral fluids (OF) and urine can serve as alternative, non-invasive samples to diagnose chikungunya virus (CHIKV) infection via RT-qPCR, we employed the same RNA extraction and RT-qPCR protocols on paired serum, OF and urine samples ...
Leile Camila Jacob-Nascimento +8 more
doaj +1 more source
RT-qPCR expression of chosen genes from RNA-Seq.
, 2022 Testis expression of 15 genes measured with RNA-Seq and RT-qPCR of dominant fish compared to subordinate fish. Values are expressed as log2fold change +/- SEM. Significant differences for RT-qPCR data was determined via ANOVA. * = p< 0.05.
Berta Levavi-Sivan (2456017) +3 more
core +1 more source
USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival
Molecular Oncology, EarlyView.CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna +8 more
wiley +1 more source
Journal of Rawalpindi Medical CollegeObjective: The objective of this study was to compare the diagnostic accuracy of RT-qPCR in endometrial cancer using novel biomarkers in clinical specimens, keeping immunohistochemical analysis as the gold standard.
Sampana Fatima +4 more
doaj +1 more source