Custom RT-qPCR-array for glaucoma filtering surgery prognosis. [PDF]
PLoS ONE, 2017 Excessive subconjunctival scarring is the main reason of failure of glaucoma filtration surgery. We analyzed conjunctival and systemic gene expression patterns after non penetrating deep sclerectomy (NPDS). To find expression patterns related to surgical
Iñaki Rodriguez-Agirretxe +4 more
doaj +1 more source
Considerations for optimization of microRNA PCR assays for molecular diagnosis [PDF]
, 2016 The remarkable stability of microRNAs in biofluids underlies their potential as biomarkers, but their small size presents challenges for detection by RT-qPCR.
Dellett, Margaret, Simpson, David Arthur
core +1 more source
Prognostic value of CIP2A gene expression in adult Egyptian acute myeloid leukemia patients
Egyptian Journal of Medical Human Genetics, 2020 Background Protein phosphatase 2A (PP2A) functions as a tumor suppressor in many cancers. Cancerous inhibitor of protein phosphatase 2A (CIP2A) inhibits PP2A proteolytic degradation of c-Myc and enhances cell growth and tumor formation in several tissues.
Roxan E. Shafik +5 more
doaj +1 more source
Aberrant Autophagic Response in The Muscle of A Knock-in Mouse Model of Spinal and Bulbar Muscular Atrophy [PDF]
, 2015 Spinal and bulbar muscular atrophy (SBMA) is characterized by loss of motoneurons and sensory neurons, accompanied by atrophy of muscle cells. SBMA is due to an androgen receptor containing a polyglutamine tract (ARpolyQ) that misfolds and aggregates ...
Aggarwal, Tanya +15 more
core +2 more sources
Zika virus promotes CCN1 expression via the CaMKIIα-CREB pathway in astrocytes. [PDF]
, 2020 Zika virus (ZIKV) infection in the human central nervous system (CNS) causes Guillain-Barre syndrome, cerebellum deformity, and other diseases. Astrocytes are immune response cells in the CNS and an important component of the blood-brain barrier ...
Hu, Q +12 more
core +1 more source
The dual nature of trehalose in citrus canker disease: A virulence factor for Xanthomonas citri subsp. citri and a trigger for plant defence responses [PDF]
, 2015 Xanthomonas citri subsp. citri (Xcc) is a bacterial pathogen that causes citrus canker in susceptible Citrus spp. The Xcc genome contains genes encoding enzymes from three separate pathways of trehalose biosynthesis.
Feil, Regina +10 more
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Diagnosis of reovirus infection in broiler breeders flocks by using PCR technique in Erbil province [PDF]
Iraqi Journal of Veterinary Sciences, 2020 Avian reoviruses can infect birds without any clinical signs of infection, the infection may associate with different manifestations including viral arthritis/tenosynovitis and malabsorption syndrome.
Fanar Isihak
doaj +1 more source
How to perform RT-qPCR accurately in plant species?: a case study on flower colour gene expression in an azalea (Rhododendron simsii hybrids) mapping population [PDF]
, 2013 Background: Flower colour variation is one of the most crucial selection criteria in the breeding of a flowering pot plant, as is also the case for azalea (Rhododendron simsii hybrids).
De Keyser, Ellen +3 more
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Evaluation of relative quantification of alternatively spliced transcripts using droplet digital PCR [PDF]
, 2017 Introduction: For the relative quantification of isoform expression, RT-qPCR has been the gold standard for over a decade. More recently, digital PCR is becoming widely implemented, as it is promised to be more accurate, sensitive and less affected by ...
Baert, Annelot +8 more
core +3 more sources