Results 41 to 50 of about 2,314 (174)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Integration of GNSS technologies into the geodesic monitoring and mining transport management system

Технічна інженерія
The paper examines the theoretical, methodological, and practical aspects of integrating GNSS technologies into the geodetic monitoring and mining transport management system within the context of the mining industry’s digital transformation.
A.V. Panasiuk, V.O. Shlapak, D.O. Tarnavsky, Ya.R. Shapar   +3 more
doaj   +1 more source

INŽINERINIŲ OBJEKTŲ KOORDINAČIŲ NUSTATYMO GALIMYBĖS IR KOKYBĖ GPNS RTK MATAVIMAIS ĮVAIRIOMIS SĄLYGOMIS

Mokslo Taikomieji Tyrimai Lietuvos Kolegijose, 2021
Statybos planavimo ir valdymo veikloje taikomos technologijos, susijusios su įvairiomis erdvinių duomenų kombinacijomis, iš kurių gaunami reikšmingi rezultatai apie tiriamą objektą.
Vilma Kriaučiūnaitė-Neklejonovienė, Donatas Rekus   +1 more
doaj  

Consistency Analysis of RTK and Non-RTK UAV DSMs in Vegetated Areas

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing, 2023
Lately, unmanned aerial vehicles (UAVs) evolve into one of the most popular remote sensing technologies by providing rapid and periodical acquisition of high-resolution, accurate, and low-cost aerial data. Progressively, the technology of UAVs rises with the addition of advanced equipment such as multispectral (MS) digital cameras and global navigation
Umut Gunes Sefercik, Mertcan Nazar
openaire   +2 more sources

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Lelkészeknek – a lelkészkép – lelkészi identitás kérdése az önértelmezésünk rögös útján –

Studia Universitatis Babeş-Bolyai. Theologia Reformata Transylvanica, 2016
The Problem of Self-image and Identity by Pastors. The problem of self-image and identity is an issue that seems to trouble theologian more and more, but pastors less and less.
Miklós KOCSEV
doaj  

GNSS techniques for real-time monitoring of landslides: a review

Satellite Navigation, 2023
Currently, Global Navigation Satellite System (GNSS) Real-Time Kinematic positioning (RTK) and Precise Point Positioning (PPP) techniques are widely employed for real-time monitoring of landslides.
Guanwen Huang, Shi Du, Duo Wang
doaj   +1 more source

GNSS-RTK Adaptively Integrated with LiDAR/IMU Odometry for Continuously Global Positioning in Urban Canyons

Applied Sciences, 2022
Global Navigation Satellite System Real-time Kinematic (GNSS-RTK) is an indispensable source for the absolute positioning of autonomous systems. Unfortunately, the performance of the GNSS-RTK is significantly degraded in urban canyons, due to the ...
Jiachen Zhang, Weisong Wen, Feng Huang, Yongliang Wang, Xiaodong Chen, Li-Ta Hsu   +5 more
doaj   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source