Results 91 to 100 of about 52,415 (197)

RUNX2 associated long non-coding RNA characterization [PDF]

, 2018
RUNX2 is a lineage-specific transcription factor (TF) known to promote cancer progression. However, the molecular mechanisms that control RUNX2 expression in cancer remain widely unknown.
Rossi, Teresa
core  

Runx2 regulates peripheral nerve regeneration to promote Schwann cell migration and re-myelination

Neural Regeneration Research
Runx2 is a major regulator of osteoblast differentiation and function; however, the role of Runx2 in peripheral nerve repair is unclear. Here, we analyzed Runx2 expression following injury and found that it was specifically up-regulated in Schwann cells.
Rong Hu, Xinpeng Dun, Lolita Singh, Matthew C Banton   +3 more
doaj   +1 more source

Hepatocyte growth factor-induced BMP-2 expression is mediated by c-Met receptor, FAK, JNK, Runx2, and p300 pathways in human osteoblasts

, 2012
[[abstract]]Hepatocyte growth factor (HGF) has been demonstrated to stimulate osteoblast proliferation and participated bone remodeling. Bone morphogenetic protein-2 (BMP-2) is a crucial mediator in bone formation during fracture healing.
黃元勵;Huang, Yuan-Li
core  

Effects of selenium-mediated RUNX2 overexpression and its transcriptome alterations on Chondrocyte injury in Kashin Beck disease

Frontiers in Cell and Developmental Biology
ObjectiveKashin-Beck disease (KBD) is a nutrition-related osteoarthropathy characterized by excessive apoptosis and matrix destruction. Micronutrient selenium (Se) deficiency is recognized as a major environmental risk factor.
Di Zhang, Di Zhang, Qiang Li, Xiaoli Yang, Yongmin Xiong, Shiquan Sun   +5 more
doaj   +1 more source

The Pathogenic Potential of RUNX2

Exploratory Research and Hypothesis in Medicine, 2021
Lihua Ni, Cheng Yuan
openaire   +1 more source

Runx2 acetylation enhances pulmonary inflammation in chronic obstructive pulmonary disease through activating CDK8

Respiratory Research
Background Runt-related transcription factor 2 (Runx2), a transcription factor of the RUNX family, is involved in various inflammatory diseases. However, the role of Runx2 was unclear in chronic obstructive pulmonary disease (COPD).
Yi-Cheng Ma, Dan-Lei Chen, Ju-Hong Wu, Fei Tang, Tian-Rui Sui, Zhi-Yong Wu, Qi-Yuan He, Yu Wang, Min-Min Tang, Dong-Xu Hua, Jing Yang, Hui Zhao, Jun Fei, Wei Cao, Lin Fu   +14 more
doaj   +1 more source

The RUNX2 Cistrome in Osteoblasts [PDF]

Journal of Biological Chemistry, 2014
Mark B. Meyer, Nancy A. Benkusky, J. Wesley Pike   +2 more
openaire   +1 more source

ROLE OF RUNX2 IN PROSTATE CANCER PROGRESSION

, 2012
Prostate cancer (PC) is a leading cause of death for men because of metastasis of the tumor to the skeleton. Using mouse models, we find that Runx2, a transcription factor implicated in PC progression, is present in stromal and epithelial cells of the ...
King, Catherine Georgia
core   +2 more sources

RUNX2 Gene [PDF]

, 2020
openaire   +1 more source

Runx2 발현억제를 통한 전사인자 Snail의 골분화조절

, 2010
Dept. of Medical Science/박사[한글] [영문]Osteoblasts originate from mesenchymal stem cells by the coordinated activities of different signaling pathways that regulate the expression of osteoblast-specific genes. Runt-related transcription factor 2 (Runx2) is
박수진
core