Results 101 to 110 of about 52,415 (197)

SCF^JFK regulates osteoblast differentiation through targeting RUNX2. [PDF]

Signal Transduct Target Ther
Shang Z, Zhang Y, Liu Y, Yuan X, Wang J, Fan D, Zou D, Tie D, Pei F, Zhao H, Zheng S, Tang X, Li W, He L.   +13 more
europepmc   +1 more source

Chromatin Remodeller BRD9 Orchestrates Odontoblastic Differentiation via Coordinating RUNX2-KLF4. [PDF]

Cell Prolif
Zeng W, Lin Y, Gao Y, Huang D, Li Y, Ruan H, Yuan G, Liu H, Chen Z.   +8 more
europepmc   +1 more source

Role of ATOH8 in Mitigating Cardiac Fibrosis in Heart Failure via Inhibition of the Transcriptional Repression of Smad7 by RUNX2. [PDF]

Biomol Ther (Seoul)
Chen C, Yang Y, Yang C, Gao C, Liu Y, Yang H, Wang X, Zhang Y, Ge Z.   +8 more
europepmc   +1 more source

MACF1 Mediates the Impairment of Mechanical Unloading on Osteoblast Differentiation via F-Actin/ERK/Runx2 Axis. [PDF]

Cells
Hu L, Ru K, Zhong W, Wang L, Huang Z, Qiao L, Chen Z, Qian A.   +7 more
europepmc   +1 more source

RUNX2 inhibitor CADD522 improves bone microarchitecture and lipid metabolism in post-menopausal bone loss. [PDF]

NPJ Drug Discov
Ersek A, Kim MS, Suelzu C, Piec I, Matsangos A, Nurmemmedov E, Bull EC, Bartlett T, Dunn R, Dick JR, Lapidus R, Copeman DM, Tang JCY, Crichton PG, Pontifex MG, Fraser WD, Horwood NJ, Passaniti A, Green D.   +18 more
europepmc   +1 more source

Neddylation of NFATc1 and Runx2 regulates osteoclast-osteoblast balance and represents a dual-action therapeutic target for postmenopausal osteoporosis. [PDF]

Exp Mol Med
Lee J, Lee MY, Kim HS, Park JW, Moon GH, Park JB, Kim HJ, Kim SJ, Chun YS.   +8 more
europepmc   +1 more source

Critical role of cellular communication network factor 1 in early osteogenesis of mesenchymal stem cells primed by low-intensity pulsed ultrasound and bone morphogenetic protein 2. [PDF]

J Cell Commun Signal
Paing HM, Kubota S, Takigawa M, Kuboki T, Nishida T.   +4 more
europepmc   +1 more source

Targeting the Ip6k2-Runx2 axis disrupts osteoblast-osteoclast coupling to treat osteoporosis. [PDF]

Nat Commun
Ma G, Chen Y, Cheng S, Wang F, Han Y, Chen L, Ding Z, Li Y, Cao H.   +8 more
europepmc   +1 more source

Analysis of the transcription Factor RUNX2, especially the RUNX2-Cbfß interaction in the pathogenesis of cleidocranial dysplasia

, 2006
RUNX2, auch als CBFA1, OSF2 und AML-3 bezeichnet, ist ein für die Knochenentwicklung essentieller Transkriptionsfaktor. Mäuse, die einen homozygoten Defekt des RUNX2 Gens aufweisen (Runx-/-), zeigen einen vollständigen Block in der ...
Schäfer, Henning Sebastian
core  

Cleidocranial dysplasia with preserved function under conservative management: a case report. [PDF]

Front Pediatr
Xu H, Ma J, Huang X, Pu S, Hou F, Liu W, Chen J.   +6 more
europepmc   +1 more source