Results 11 to 20 of about 1,363 (148)

in silico Study Reveals Potential Docking Sites of δ 2-isoxazolines derivates for Inhibiting Russell’s Viper PLA2 Toxin

Journal of Tropical Life Science, 2021
Snake venom phospholipase A2s (svPLA2s) has been known as the most abundant component and predominant cause of Russell’s viper envenomation. Limitation to serum therapy and considerable pharmacological interest led the researcher to synthesized multi-toxic PLA2 inhibitors, δ2-isoxazolines derivate.
Tsaniyah Nur Kholilah, Widodo, Nia Kurniawan   +2 more
openaire   +2 more sources

Acute Myocardial Infarction following a possible direct intravenous bite of Russell’s viper (Daboia russelli) [PDF]

BMC Research Notes, 2012
Background Russell’s viper (Daboia russelli) bites lead to high morbidity and mortality in South Asia. Although variety of clinical manifestations is reported in viper bite victims, myocardial ischemic events are rare.
Silva Anjana, Pilapitiya Senaka, Siribaddana Sisira   +2 more
doaj   +2 more sources

Pulmonary Thromboembolism following Russell’s Viper Bites [PDF]

Toxins
Snakebite envenoming and its resulting complications are serious threats to the health of vulnerable people living in rural areas of developing countries.
Subramanian Senthilkumaran, Sasikumar Sampath, José R. Almeida, Jarred Williams, Harry F. Williams, Ketan Patel, Ponniah Thirumalaikolundusubramanian, Sakthivel Vaiyapuri   +7 more
doaj   +2 more sources

Differential effects of the venoms of Russell’s viper and Indian cobra on human myoblasts [PDF]

Scientific Reports
Local tissue damage following snakebite envenoming remains a poorly researched area. To develop better strategies to treat snakebites, it is critical to understand the mechanisms through which venom toxins induce envenomation effects including local ...
Husain Bin Haidar, José R. Almeida, Jarred Williams, Bokai Guo, Anne Bigot, Subramanian Senthilkumaran, Sakthivel Vaiyapuri, Ketan Patel   +7 more
doaj   +2 more sources

A case report of peritoneal dialysis for management of acute kidney injury caused by Russell’s viper envenomation in a dog

Veterinary Integrative Sciences, 2021
This report describes a five-year-old dog who had been bitten by a Russell’s viper. The patient presented clinical signs of anorexia, vomiting, lethargy, and anuria.
Tanamon Poppinit, Chanakarn SungThong
doaj   +3 more sources

Lowly Expressed Toxin Transcripts in Poorly Characterized Myanmar Russell’s Viper Venom Gland [PDF]

BioTech
In Myanmar, Russell’s viper (Daboia siamensis) bite is a significant public health problem. In this study, we expend upon our previous RNA-sequencing approach to characterize candidate toxin genes encoding D. siamensis toxins. The mRNA was extracted from
Khin Than Yee, Jason Macrander, Olga Vasieva, Ponlapat Rojnuckarin   +3 more
doaj   +2 more sources

Clinico-epidemiology and management of Russell’s viper (Daboia russelii) envenoming in dogs in Sri Lanka [PDF]

Toxicology Reports, 2019
Introduction: Russell’s viper envenoming in dogs is a significant problem in Sri Lanka. The current study focused on investigating clinical profile, laboratory findings of three selected tests and to develop a treatment strategy with Indian polyvalent ...
Ranjith B. Adhikari, Indika B. Gawarammana, D.D.N. De Silva, Ashoka Dangolla, Chandima Mallawa, A.D. Premarathna, Indira D Silva   +6 more
doaj   +2 more sources

Clinical and Pharmacological Investigation of Myotoxicity in Sri Lankan Russell's Viper (Daboia russelii) Envenoming. [PDF]

PLoS Neglected Tropical Diseases, 2016
BACKGROUND:Sri Lankan Russell's viper (Daboia russelii) envenoming is reported to cause myotoxicity and neurotoxicity, which are different to the effects of envenoming by most other populations of Russell's vipers.
Anjana Silva, Christopher Johnston, Sanjaya Kuruppu, Daniela Kneisz, Kalana Maduwage, Oded Kleifeld, A Ian Smith, Sisira Siribaddana, Nicholas A Buckley, Wayne C Hodgson, Geoffrey K Isbister   +10 more
doaj   +3 more sources

Evaluation of the geographical utility of Eastern Russell's viper (Daboia siamensis) antivenom from Thailand and an assessment of its protective effects against venom-induced nephrotoxicity.

PLoS Neglected Tropical Diseases, 2019
BackgroundDaboia siamensis (Eastern Russell's viper) is a medically important snake species found widely distributed across Southeast Asia. Envenomings by this species can result in systemic coagulopathy, local tissue injury and/or renal failure.
Janeyuth Chaisakul, Jaffer Alsolaiss, Mongkon Charoenpitakchai, Kulachet Wiwatwarayos, Nattapon Sookprasert, Robert A Harrison, Narongsak Chaiyabutr, Lawan Chanhome, Choo Hock Tan, Nicholas R Casewell   +9 more
doaj   +3 more sources

Evaluation of the effect of apixaban using a viscoelastic coagulation assay with Russell’s viper venom reagent [PDF]

JA Clinical Reports, 2021
Background Conventional coagulation tests, such as prothrombin time and activated partial thromboplastin time, are not sensitive to anticoagulation by apixaban. We evaluated the antithrombotic effect of apixaban using a Russell viper venom (RVV) test for
Kaoru Suzuki, Nobuyuki Katori, Yoshihiro Kimura, Takako Terui, Hiroshi Sunaga, Shunsuke Kobayashi, Shoichi Uezono   +6 more
doaj   +2 more sources