Priapism following a juvenile Russell's viper bite: An unusual case report. [PDF]
PLoS Negl Trop Dis, 2021 Following a bite from a juvenile Russell’s viper (Daboia russelii), a priapism (painful erection) developed rapidly in a 16-year-old male and only subsided after administration of antivenom 3 hours later.
Senthilkumaran S +5 more
europepmc +4 more sources
Snake Venom Metalloproteinases and Their Peptide Inhibitors from Myanmar Russell’s Viper Venom [PDF]
Toxins, 2016 Russell’s viper bites are potentially fatal from severe bleeding, renal failure and capillary leakage. Snake venom metalloproteinases (SVMPs) are attributed to these effects.
Khin Than Yee +4 more
doaj +4 more sources
Venom proteomics and antivenom neutralization for the Chinese eastern Russell's viper, Daboia siamensis from Guangxi and Taiwan. [PDF]
Sci Rep, 2018 The eastern Russell’s viper (Daboia siamensis) causes primarily hemotoxic envenomation. Applying shotgun proteomic approach, the present study unveiled the protein complexity and geographical variation of eastern D.
Tan KY, Tan NH, Tan CH.
europepmc +4 more sources
A Biochemical and Pharmacological Characterization of Phospholipase A2 and Metalloproteinase Fractions from Eastern Russell’s Viper (Daboia siamensis) Venom: Two Major Components Associated with Acute Kidney Injury [PDF]
Toxins, 2021 Acute kidney injury (AKI) following Eastern Russell’s viper (Daboia siamensis) envenoming is a significant symptom in systemically envenomed victims.
Janeyuth Chaisakul +10 more
doaj +3 more sources
A Bayesian phase 2 model based adaptive design to optimise antivenom dosing: Application to a dose-finding trial for a novel Russell's viper antivenom in Myanmar. [PDF]
PLoS Negl Trop Dis, 2020 For most antivenoms there is little information from clinical studies to infer the relationship between dose and efficacy or dose and toxicity. Antivenom dose-finding studies usually recruit too few patients (e.g.
Watson JA +9 more
europepmc +3 more sources
Early identification of acute kidney injury in Russell's viper (Daboia russelii) envenoming using renal biomarkers. [PDF]
PLoS Negl Trop Dis, 2019 Background Acute kidney injury (AKI) is a major complication of snake envenoming, but early diagnosis remains problematic. We aimed to investigate the time course of novel renal biomarkers in AKI following Russell’s viper (Daboia russelii) bites ...
Ratnayake I +10 more
europepmc +3 more sources
Isolation and Pharmacological Characterisation of Pre-Synaptic Neurotoxins from Thai and Javanese Russell’s Viper (Daboia siamensis) Venoms [PDF]
ToxinsThe widespread geographical distribution of Russell’s vipers (Daboia spp.) is associated with marked variations in the clinical outcomes of envenoming by species from different countries.
Mimi Lay, Wayne C. Hodgson
doaj +3 more sources
Unraveling the Reaction Mechanism of Russell's Viper Venom Factor X Activator: A Paradigm for the Reactivity of Zinc Metalloproteinases? [PDF]
J Chem Inf Model, 2023 Snake venom metalloproteinases (SVMPs) are important drug targets against snakebite envenoming, the neglected tropical disease with the highest mortality worldwide.
Castro-Amorim J +4 more
europepmc +2 more sources
Thrombotic microangiopathy, hemolytic uremic syndrome and thrombotic thrombocytopenic purpura: Rare manifestations of Russell’s viper (Daboia russelii) envenoming in Sri Lanka [PDF]
Asia Pacific Journal of Medical Toxicology, 2021 Background: Russell’s viper (Daboia russelii) of Family Viperidae is a highly venomous snake in Sri Lanka and is responsible for the most snakebite deaths. It commonly causes coagulopathy and neuroparalysis. Thrombotic microangiopathy (TMA) including the
R.M.M.K.Namal Rathnayaka +2 more
doaj +2 more sources
Biogeographic venom variation in Russell's viper (Daboia russelii) and the preclinical inefficacy of antivenom therapy in snakebite hotspots. [PDF]
PLoS Negl Trop Dis, 2021 Background Snakebite in India results in over 58,000 fatalities and a vast number of morbidities annually. The majority of these clinically severe envenomings are attributed to Russell’s viper (Daboia russelii), which has a near pan-India distribution ...
Senji Laxme RR +8 more
europepmc +2 more sources