Results 61 to 70 of about 1,363 (148)

Utility of clot waveform analysis in Russell's viper bite victims with hematotoxicity

open access: yesJournal of Emergencies, Trauma and Shock, 2018
Introduction: In Russell's viper bites, due to the lack of a better alternative, whole blood clotting test (WBCT) remains the standard test even though its reliability and sensitivity has been shown to be low. Activated partial thromboplastin time (aPTT)-
Siju V Abraham   +6 more
doaj   +1 more source

Autoimmune Thrombocytopenia Treated by Low‐Dose Splenic Irradiation Followed by Splenectomy in a Patient With Systemic Lupus Erythematosus

open access: yesClinical Case Reports, Volume 13, Issue 12, December 2025.
ABSTRACT Severe autoimmune thrombocytopenia (ATP) in systemic lupus erythematosus (SLE) patients can be life‐threatening when refractory to standard treatments. Low‐dose splenic irradiation (LDSI) can provide temporary platelet recovery before definitive splenectomy.
Ryosuke Hanaoka
wiley   +1 more source

Thrombolytic Therapy for Massive Pulmonary Embolism in an Antiphospholipid Syndrome Patient With Severe Thrombocytopenia: A Case Report

open access: yesClinical Case Reports, Volume 13, Issue 11, November 2025.
ABSTRACT Thrombocytopenia (TCP) is a well‐known contraindication for thrombolytic therapy due to the associated risk of bleeding. This report discusses a 34‐year‐old woman presented with massive pulmonary embolism (PE) and severe TCP. She was treated with systemic thrombolysis (ST), and fortunately, a good therapeutic response was achieved without ...
Arman Ahmadzadeh   +5 more
wiley   +1 more source

IgG and IgM Anti‐Phosphatidylserine/Prothrombin Complex Antibody Detection May Improve Classification Accuracy of Systemic Lupus Erythematosus and Antiphospholipid Antibody Syndrome

open access: yesACR Open Rheumatology, Volume 7, Issue 10, October 2025.
Objective Antiphospholipid antibody (aPL) syndrome (APS) classification requires a thrombotic event and detection of lupus anticoagulant (LAC), anticardiolipin antibodies (aCL), or anti–β2‐glycoprotein I (anti‐β2GPI) antibodies on two occasions ≥12 weeks apart. Here, we investigated the utility of anti–phosphatidylserine/prothrombin complex (anti‐PS/PT)
Christina Donath   +4 more
wiley   +1 more source

Therapeutic Plasma Exchange After Spontaneous Intracranial Hemorrhage for a Patient With Antiphospholipid Syndrome and Lupus Anticoagulant Hypoprothrombinemia

open access: yesJournal of Clinical Apheresis, Volume 40, Issue 5, October 2025.
ABSTRACT Antiphospholipid syndrome (APS) is characterized by the presence of antiphospholipid antibodies (aPL), macro‐ and micro‐vascular thromboembolic complications. Lupus anticoagulant‐hypoprothrombinemia (LAHPS) may confound the diagnosis and management of bleeding. Catastrophic APS has a category 1 indication for therapeutic plasma exchange (TPE).
Joshua Nicholas   +4 more
wiley   +1 more source

Understanding Suitable Habitats and Anthropogenic Mortality Risks for King Cobras in Nepal

open access: yesEcology and Evolution, Volume 15, Issue 9, September 2025.
The king cobra (Ophiophagus hannah), a vulnerable species, faces significant habitat loss and mortality risks in Nepal. Using ensemble modeling with 553 occurrence records, this study identified 23,702.62 km2 of suitable habitat, projecting up to 22% habitat loss by 2050 under SSP2‐4.5 climate scenarios.
Rishi Baral   +11 more
wiley   +1 more source

Novel role of antiplatelet agents (aspirin plus clopidogrel) in an incoagulable blood of a victim of russell's viper snakebite

open access: yesJournal of Venomous Animals and Toxins including Tropical Diseases, 2006
Snake antivenom is a specific antidote to the venom action, neutralizing the circulating venom. However, it fails to neutralize the venom fixed to target organs such as platelets, renal tubules, etc. Russell's viper venom initiates rapid coagulation in a
H. S. Bawaskar
doaj   +1 more source

Activated Protein C Resistance Testing: An Update From Australasia/Asia‐Pacific

open access: yesInternational Journal of Laboratory Hematology, Volume 47, Issue 4, Page 720-729, August 2025.
ABSTRACT Introduction Activated protein C resistance (APCR) represents a risk factor for thrombosis and is usually due to factor V Leiden (FVL). Clinicians may order either test (i.e., APCR or FVL) to help assess ‘thrombophilia’ in patients who present with thrombosis. APCR testing is usually achieved using clot‐based assays, whereas FVL is assessed by
Emmanuel J. Favaloro   +8 more
wiley   +1 more source

One Bite, Two Severe Envenomations Despite Antivenom Therapy: A Case Report

open access: yesClinical Case Reports, Volume 13, Issue 7, July 2025.
ABSTRACT This case report describes a 12‐year‐old child who was bitten by a cobra and developed two distinct systemic neurotoxic episodes, 19 h apart, along with severe local envenoming, despite receiving appropriate treatment with antivenom and making a full recovery.
Ravi Shukla   +4 more
wiley   +1 more source

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