Results 1 to 10 of about 18,824 (262)
Rationally Designed Ruthenium Complexes for Breast Cancer Therapy [PDF]
Molecules, 2020 Since the discovery of the anticancer potential of ruthenium-based complexes, several species were reported as promising candidates for the treatment of breast cancer, which accounts for the greatest number of new cases in women every year worldwide ...
Golara Golbaghi, Annie Castonguay
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Metal Ruthenium Complexes Treat Spinal Cord Injury By Alleviating Oxidative Stress Through Interaction With Antioxidant 1 Copper Chaperone Protein [PDF]
Advanced ScienceOxidative stress is a major factor affecting spinal cord injury (SCI) prognosis. A ruthenium metal complex can aid in treating SCI by scavenging reactive oxygen species via a protein‐regulated mechanism to alleviate oxidative stress.
Juanjuan Li +10 more
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Special Issue on Ruthenium Complexes
Molecules, 2017 The organic chemistry of ruthenium has been one of the most vigorously growing research areas over the past decades. Considerable effort has been extended towards the design and application of a broad series of ruthenium complexes, which culminated with ...
Ileana Dragutan +2 more
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Molecules, 2021 Metal complexes have been used to treat cancer since the discovery of cisplatin and its interaction with DNA in the 1960’s. Facing the resistance mechanisms against platinum salts and their side effects, safer therapeutic approaches have been sought ...
Christian Gaiddon +9 more
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Synthesis, spectral, dna binding and cleavage properties of ruthenium(II) Schiff base complexes containing PPh3/AsPh3 as co-ligands [PDF]
Journal of the Serbian Chemical Society, 2014 A dihydroxybenzaldehyde Schiff base ligands (L1-L3) and its ruthenium(II) complexes, have been synthesized and characterized on the basis of elemental analysis, 1H, 13C, 31P NMR, mass spectra, UV-vis and IR spectra.
Sathiyaraj Subbaiyan +2 more
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Ruthenium(II) dimethyl sulphoxide based complexes: A potent inducer of apoptosis
Results in Chemistry, 2022 Ruthenium (Ru) Dimethylsulphoxide complexes have appeared as a prominent compound among the potential metal-based drug for the cure of cancer. Cancer is marked with the uncontrolled proliferative activity that can be treated with apoptosis inducers ...
Sunita Khatkar +7 more
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Biological Activities of Ruthenium NHC Complexes: An Update
Antibiotics, 2023 Ruthenium N-heterocyclic carbene (NHC) complexes have unique physico-chemical properties as catalysts and a huge potential in medicinal chemistry and pharmacology, exhibiting a variety of notable biological activities.
Alessia Catalano +6 more
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Molecules, 2022 In these studies, we investigated the antioxidant activity of three ruthenium cyclopentadienyl complexes bearing different imidato ligands: (η5-cyclopentadienyl)Ru(CO)2-N-methoxysuccinimidato (1), (η5-cyclopentadienyl)Ru(CO)2-N-ethoxysuccinimidato (2 ...
Michał Juszczak +4 more
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Chemistry of Inorganic Materials, 2023 A new series of pincer type ruthenium(II) Schiff base complexes namely [Ru(CO)(PPh3)2(L1‒6)] (1–6) (where, L1‒6 = NOO ‒ donors of tri-dentate ligands) have been synthesized from ruthenium precursor such as [RuHCl(CO)(PPh3)3] containing tri-dentate ...
Premkumar Muniyappan +2 more
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Applications of Ruthenium Complex in Tumor Diagnosis and Therapy
Frontiers in Pharmacology, 2018 Ruthenium complexes are a new generation of metal antitumor drugs that are currently of great interest in multidisciplinary research. In this review article, we introduce the applications of ruthenium complexes in the diagnosis and therapy of tumors.
Ke Lin +4 more
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