Development of a non-invasive method to detect pericellular spatial oxygen gradients using FLIM [PDF]
PhDExtracellular oxygen concentrations affect cellular metabolism and influence tissue function. Detection methods for these extracellular oxygen concentrations currently have poor spatial resolution and are frequently invasive.
Hosny, Neveen Amera
core +4 more sources
Probing ground and excited state properties of ruthenium (II) and osmium (II) polypyridyl complexes [PDF]
The area of ruthenium(H) and osmium(H) polypyridyl chemistry has been the subject of intense investigation over the last half century. In chapter 1, topics relevant to the studies presented in this thesis are introduced.
Browne, Wesley R.
core +2 more sources
Anticancer and antiproliferative activity of ruthenium complex (II) bearing 3,3’-dicarboxy-2,2’-bipyridine ligand [PDF]
Even though significant progress has been made in cancer treatment, there is always room for improvement. The experimental drug Ruthenium Complex II shows promise as a cancer treatment.
Mohamed Saadh
doaj +3 more sources
Functionalization of osmium arene anticancer complexes with (poly)arginine : effect on cellular uptake, internalization, and cytotoxicity [PDF]
Attaching peptides to metallodrugs may result in improved biological properties of the complexes. The potential use of cell penetrating peptides (CPPs) as cell delivery vectors is attractive, since directed cell uptake of (metallo)drugs remains a major ...
Rijt, Sabine H. van +7 more
core +1 more source
Somatostatin subtype-2 receptor-targeted metal-based anticancer complexes [PDF]
Conjugates of a dicarba analogue of octreotide, a potent somatostatin agonist whose receptors are overexpressed on tumor cells, with [PtCl 2(dap)] (dap = 1-(carboxylic acid)-1,2-diaminoethane) (3), [(η 6-bip)Os(4-CO 2-pico)Cl] (bip = biphenyl, pico ...
González, Carlos A. +24 more
core +1 more source
Photoactive ruthenium-based complexes are actively studied for their biological applications as potential theragnostic agents against cancer. One major issue of these inorganic complexes is to penetrate inside cells in order to fulfil their function ...
Sofia Kajouj +12 more
doaj +1 more source
We report the synthesis, characterization and electrochemical studies of four ruthenium(II) complexes of mixed bipyridyl and dithiolate ligands. The complexes formulated as [Ru(L1)(dcbpy)], [Ru(L2)(dcbpy)], [Ru(L3)(dcbpy)] and [Ru(L4)(dcbpy)] where L1 ...
Pelokazi Nkombi +3 more
doaj +1 more source
Bacterial resistance to antibiotics is an ever-growing problem in heathcare. We have previously identified a set of osmium(II), ruthenium(II), iridium(III) and rhodium(III) half-sandwich type complexes with bidentate monosaccharide ligands possessing ...
Bence Balázs +11 more
doaj +1 more source
Osmium(II) and Ruthenium(II) complexes of tricyclohexylphosphine [PDF]
AbstractThe preparation of tricyclohexylphosphine complexes of osmium and ruthenium is reported. The reaction of K2OsCl6 or hydrated RuCl3 with tricyclohexylphosphine (PCy3) in 2‐methoxyethanol leads to the complexes MHCl(CO) (PCy3)2 with M = Os or Ru.
Moers, F.G., Langhout, J.P.
openaire +3 more sources
Synthesis and characterisation of a series of novel mononuclear and surface active dinuclear ruthenium (II) and osmium (II) polypyridyl complexes [PDF]
The synthesis, spectroscopic and electrochemical characterisation of a series of mononuclear and dinuclear ruthenium (II) and osmium (II) complexes is described. Chapter 1 provides an introduction to the area of supramolecular chemistry.
Guckian, Adrian Liam
core +1 more source

