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Microbial Degradation of Rutin

Nature, 1959
COMPARATIVELY little work on the metabolism of rutin has been published. 3,4-dihydroxyphenyl acetic acid and homovanillic acid are found in urine after oral administration of rutin to the rat1,2, and protocatechuic acid accumulates in rat kidney homogenates in the presence of quercetin3.
S, HATTORI, I, NOGUCHI
exaly   +3 more sources

Rutin: a pain-relieving flavonoid

Inflammopharmacology
Rutin (vitamin P or rutoside) is a citrus flavonoid glycoside that has shown beneficial health effects in different organs against various conditions including inflammation and pain. The majority of rutin therapeutic benefits are ascribed to its antioxidant and anti-inflammatory properties.
Fatemeh Forouzanfar   +4 more
openaire   +3 more sources

Rutin alleviates EndMT by restoring autophagy through inhibiting HDAC1 via PI3K/AKT/mTOR pathway in diabetic kidney disease.

Phytomedicine, 2023
BACKGROUND Diabetic kidney disease (DKD) is a primary microvascular complication of diabetes. However, a complete cure for DKD has not yet been found.
Ruixue Dong   +11 more
semanticscholar   +1 more source

Carrier-Free Nanodrug Based on Co-Assembly of Methylprednisolone Dimer and Rutin for Combined Treatment of Spinal Cord Injury.

ACS Nano, 2023
Spinal cord injury (SCI), which is characterized by excessive inflammatory cell infiltration and accumulation of oxidative substance, would severely impede neurological functional recovery and lead to permanent and profound neurologic deficits and even ...
Hao Wang   +6 more
semanticscholar   +1 more source

Rutin ameliorates inflammation and improves metabolic function: A comprehensive analysis of scientific literature.

Pharmacological Research, 2022
Chronic inflammation remains an essential complication in the pathogenesis and aggravation of metabolic diseases. There is a growing interest in the use of medicinal plants or food-derived bioactive compounds for their antioxidant and anti-inflammatory ...
N. Muvhulawa   +6 more
semanticscholar   +1 more source

Rutin attenuates inflammation by downregulating AGE-RAGE signaling pathway in psoriasis: Network pharmacology analysis and experimental evidence.

International Immunopharmacology, 2023
BACKGROUND Jueyin granules (JYG) is effective against psoriasis, but its utility components are not clear. Rutin is the main monomer of JYG, its therapeutic effect and mechanism on psoriasis need to be further clarified.
Ming-xia Wang   +10 more
semanticscholar   +1 more source

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