Results 1 to 10 of about 12,767 (235)

The power, potential of real-world data in randomized controlled trials: proceedings from a multistakeholder think tank [PDF]

Trials
Randomized controlled trials (RCTs) remain the gold standard for evaluating medical interventions, but they often face challenges related to patient recruitment, cost, and efficiency.
Nina Nouhravesh, Jennifer G. Jackman, Adrian F. Hernandez, Charles Lee, Christoph P. Hornik, Emily Zacherle, Joanne Waldstreicher, Noelle Cocoros, Samuel Brown, Tor Biering-Sorensen, Karen Chiswell, Lisa Wruck, Stefan K. James   +12 more
doaj   +2 more sources

sFlt-1/PlGF ratio for prediction of preeclampsia in clinical routine: A pragmatic real-world analysis of healthcare resource utilisation.

PLoS ONE, 2022
BackgroundWe investigated the impact of the soluble fms-like tyrosine kinase 1 (sFlt-1)/placental growth factor (PlGF) ratio to predict short-term risk of preeclampsia on clinical utility and healthcare resource utilisation using real-world data (RWD ...
Anne Dathan-Stumpf, Anna Rieger, Stefan Verlohren, Cyrill Wolf, Holger Stepan   +4 more
doaj   +2 more sources

Transferability of real-world data across borders for regulatory and health technology assessment decision-making

Frontiers in Medicine, 2022
Recently, there has been increased consideration of real-world data (RWD) and real-world evidence (RWE) in regulatory and health technology assessment (HTA) decision-making.
Ashley Jaksa, Patrick J. Arena, Patrick J. Arena, Kelvin K. W. Chan, Kelvin K. W. Chan, Rami H. Ben-Joseph, Páll Jónsson, Ulka B. Campbell   +7 more
doaj   +1 more source

The Real-World Data Challenges Radar: A Review on the Challenges and Risks regarding the Use of Real-World Data

Digital Biomarkers, 2021
Background: The life science industry has a strong interest in real-world data (RWD), a term that is currently being used in many ways and with varying definitions depending on the source.
Frank Grimberg, Petra Maria Asprion, Bettina Schneider, Enkelejda Miho, Lmar Babrak, Ali Habbabeh   +5 more
doaj   +1 more source

Parental Perspectives on Their Grade 4 Children with Reading and Writing Difficulties in Mainstream Government Schools in Mauritius

International Journal of Education, 2021
Reading and writing difficulties (RWD) in learners pose significant challenges not just for children but also for parents. While there is limited support available for children with RWD and their parents in Mauritian schools, research may reveal areas of
Sattiavany Veerabudren, Alta Kritzinger, Marien Graham, Salomé Geertsema, Mia le Roux   +4 more
doaj   +1 more source

Real World Data in Health Technology Assessment of Complex Health Technologies

Frontiers in Pharmacology, 2022
The available evidence on relative effectiveness and risks of new health technologies is often limited at the time of health technology assessment (HTA). Additionally, a wide variety in real-world data (RWD) policies exist among HTA organizations.
Milou A. Hogervorst, Milou A. Hogervorst, Johan Pontén, Rick A. Vreman, Rick A. Vreman, Aukje K. Mantel-Teeuwisse, Wim G. Goettsch, Wim G. Goettsch   +7 more
doaj   +1 more source

The emerging role of real-world data in advanced breast cancer therapy: Recommendations for collaborative decision-making

Breast, 2022
Among stakeholders and decision-makers in advanced breast cancer, the demand for insights from real-world data (RWD) is increasing. Although RWD can be used to support decisions throughout different stages of a breast cancer drug's life cycle, barriers ...
Paul Cottu, Scott David Ramsey, Oriol Solà-Morales, Patricia A. Spears, Lockwood Taylor   +4 more
doaj   +1 more source

Best practices in the real-world data life cycle.

PLOS Digital Health, 2022
With increasing digitization of healthcare, real-world data (RWD) are available in greater quantity and scope than ever before. Since the 2016 United States 21st Century Cures Act, innovations in the RWD life cycle have taken tremendous strides forward ...
Joe Zhang, Joshua Symons, Paul Agapow, James T Teo, Claire A Paxton, Jordan Abdi, Heather Mattie, Charlie Davie, Aracelis Z Torres, Amos Folarin, Harpreet Sood, Leo A Celi, John Halamka, Sara Eapen, Sanjay Budhdeo   +14 more
doaj   +3 more sources

Review of data sources used in real-world traumatology and orthopedic

Реальная клиническая практика: данные и доказательства, 2023
Real-world data (RWD) play an increasingly important role in traumatology and orthopedics, as evidenced by the rapidly growing number of publications using registry, administrative, and other databases.
I. U. Zolotukhina, A. R. Kasimova
doaj   +1 more source

Review of real-world data study

Качественная клиническая практика, 2021
The article defines the terms «real-world data» (RWD) and «real-world evidence» (RWE); classification of RWD, advantages, disadvantages and their overcoming are outlined; provides a description of the purpose of collecting RWD.
T. A. Goldina, A. S. Kolbin, D. Yu. Belousov, V. G. Borovskaya   +3 more
doaj   +1 more source