Results 21 to 30 of about 12,767 (235)

Analyzing FDA's approaches to using electronic health record and medical claims data to support regulatory decision making

open access: yesРеальная клиническая практика: данные и доказательства, 2023
In 2021, the U.S. Food and Drug Administration (FDA) issued draft guidance on the use of electronic health records and medical claims data for regulatory decisions.
Ksenia S. Radaeva, M. V. Pchelintsev
doaj   +1 more source

Machine learning capabilities for the diagnosis of orphan diseases

open access: yesРеальная клиническая практика: данные и доказательства, 2023
Rare or orphan diseases belong to one of the most severe groups of diseases. At the same time, early and accurate diagnosis of such diseases is a serious problem for general practitioners, pediatricians and therapists.
N. Y. Dmitrieva
doaj   +1 more source

RWD based IDS for MANET

open access: yesInternational Journal of Computer Applications, 2015
Mobile Ad-Hoc network (MANET) is a temporary infrastructure less network. This network is formed by combining some set of wireless mobile hosts [1] [5]. The host is called as a node which dynamically establishes their own network. Intrusion detection in MANETs, however, is challenging for a number of reasons.
Sachin Bojewar, Kavita Varule
openaire   +1 more source

The role of real world data and real world evidence in health technology assessment

open access: yesФармакоэкономика, 2022
Real world data (RWD) and real world evidence (RWE) is one of the most rapidly developing areas in the modern health care systems, which is caused by the development of technologies for both collecting and analyzing data, the emergence of new data ...
E. A. Novoderezhkina, S. К. Zyryanov
doaj   +1 more source

Patient preferences for stages II–IV melanoma treatments in the UK: results from a cross-sectional study

open access: yesMelanoma Management
Aim To understand patient preferences for treatment attributes in adjuvant and metastatic melanoma in the UK.Materials and Methods Patients with stages II–IV melanoma completed an online survey from November 2022 to February 2023 comprising two discrete ...
Luis Vaz   +6 more
doaj   +1 more source

Impact of Different Drying Methods on the Phenolic Composition, In Vitro Antioxidant Activity, and Quality Attributes of Dragon Fruit Slices and Pulp

open access: yesFoods, 2023
The aim of this study was to compare the refractance window drying method (RWD) with the hot air oven drying (HD), vacuum drying (VD), and freeze-drying (FD) methods in order to analyze the outcomes of the qualitative properties of dragon fruit slices ...
Harsh Dadhaneeya   +6 more
doaj   +1 more source

D8.5 Participant recruitment, Preexisting RWD access, Prospective RWD acquisition and secure storage –v3

open access: yes, 2023
The Multidisciplinary Expert System for the Assessment & Management of Complex Brain Disorders (MESCoBraD) project integrates a group of professionals with inter-expertise and where a wide number of different fields of research interact. Four centres from the collaborative effort, have agreed to incorporate participant data, ranging from clinical ...
openaire   +2 more sources

Mechanoluminescent HOF Nanotransducers Enabled Sono‐Optogenetics in Parkinsonian Rats

open access: yesAdvanced Functional Materials, EarlyView.
We present a mechanoluminescent system utilizing porous hydrogen‐bonded organic frameworks (HOFs) as a toolkit for focused ultrasound‐triggered, non‐invasive light delivery to the deep brain in rats. This approach enables the specific activation of PV‐GPe neurons in dopamine‐depleted Parkinson's disease rat models, resulting in a comparable alleviation
Wenliang Wang   +18 more
wiley   +1 more source

Neutrophil‐Mimetic MRI Enables Ultra‐Early Detection of Vascular Inflammation After Stroke

open access: yesAdvanced Healthcare Materials, EarlyView.
In this study, we developed neutrophil‐mimetic MRI probes that detect ultra‐early neuroinflammation following ischemic stroke by targeting E‐selectin. Within seconds of their injection, these microparticles mimic initial leukocyte adhesion to the activated cerebral endothelium.
Marion Isabelle Morvan   +17 more
wiley   +1 more source

D8.4 Participant recruitment, Pre-existing RWD access, Prospective RWD acquisition and secure storage -v2

open access: yes, 2022
The Multidisciplinary Expert System for the Assessment & Management of Complex Brain Disorders (MESCoBraD) project integrates a group of professionals with inter-expertise and where a wide number of different fields of research interact. Four centres from the collaborative effort, have agreed to incorporate participant data, ranging from clinical ...
openaire   +1 more source

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