Results 141 to 150 of about 27,021 (267)

Beyond evidence hierarchies: Leveraging randomized controlled trials and real-world data to advance the value of maternity care. [PDF]

Acta Obstet Gynecol Scand
Value‐based maternity care decisions should draw on cost‐effectiveness evidence from both randomized controlled trials and real‐world data, integrating them systematically rather than ranking them hierarchically. Abstract While existing literature has compared the methodological strengths and limitations of randomized controlled trials (RCTs) and real ...
Hu Y, Slavin V, Enticott J, Callander E.
europepmc   +2 more sources

Collagen‐membrane‐covered matrix‐associated chondrocyte implantation improves safety over periosteum‐covered MACI for large knee cartilage defects: A real‐world data analysis in the registry study

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose This registry study aimed to evaluate the safety and effectiveness of collagen membrane‐covered matrix‐associated autologous chondrocyte implantation (cMACI) versus periosteum‐covered MACI (pMACI) for large knee cartilage defects (Outerbridge III–IV, ≥4 cm²) in the femorotibial and/or patellofemoral joints with a minimum 2‐year follow ...
Yuji Uchio, Ryosuke Kuroda, Yasuo Niki, Katsura Sugawara, Yasuyuki Ishibash   +4 more
wiley   +1 more source

LONGITUDINAL PERFORMANCE OPTIMIZATION OF RWD VEHICLE

Perner’s Contacts, 2019
The longitudinal performance of a vehicle is the ability to achieve the highest longitudinal acceleration on the given road surface and tyres. The engine is capable of high torque delivery especially in low vehicle speed. A pre-emptive controller has been deployed to control the torque delivery where tyres are being used in their peak friction area.
openaire   +1 more source

Spatiotemporal Assessment of Groundwater Interactions With a Regulated River: A Case Study of the Nechako River, Canada

River Research and Applications, EarlyView.
ABSTRACT Regulated rivers represent complex hydrological systems where groundwater–surface water interactions are governed by natural conditions and human interventions. This study investigates the spatiotemporal dynamics of groundwater–surface water exchanges in the Nechako River, British Columbia (Canada), using numerical simulations.
Milad Fakhari, John Gray, Avery Dextrase, Andre St‐Hilaire, Richard Martel   +4 more
wiley   +1 more source

Methodological guidance for the use of real-world data to measure exposure and utilization patterns of osteoporosis medications

Bone Reports
Observational studies of osteoporosis medications can provide critical real-world evidence (RWE) that fills knowledge gaps left by clinical trials. However, careful consideration of study design is needed to yield reliable estimates of association.
Kaleen N. Hayes, Suzanne M. Cadarette, Andrea M. Burden   +2 more
doaj   +1 more source

Big data in veterinary medicines regulation: A data landscape analysis to support regulatory activities

Veterinary Record, EarlyView.
Abstract Background This study describes the development of a data landscape analysis protocol that identifies and characterises animal health data sources to support key regulatory activities throughout the life cycle of veterinary medicines. Methods The protocol included: development of criteria to identify data sources; selection of variables to ...
Ewa Pacholewicz, Eduardo de Freitas Costa, Mariana Avelino de Souza Santos, Bjorn Berendsen, Jos A. A. M. Verstegen   +4 more
wiley   +1 more source

Early Identification of Cardiovascular Adverse Events Associated With Rofecoxib Using Real-World Data From the UK: A Nested Case-Control and Case-Crossover Study. [PDF]

Pharmacoepidemiol Drug Saf
ABSTRACT Background Traditional pharmacovigilance systems have limitations in detecting common adverse drug reactions. We investigated whether real‐world data (RWD) could have detected rofecoxib's cardiovascular adverse effects earlier using nested case–control (NCC) and case‐crossover (CCO) designs.
Moslemzadeh D, Souverein PC, Belitser SV, Heerdink ER, Klungel OH, Abtahi S.   +5 more
europepmc   +2 more sources

Bilateral Services Trade Data and the GTAP database [PDF]

Good statistical measurement of services trade becomes more and more important now trade in services gets the attention of policymakers. In 1995 many countries decided to liberalise services trade according to the General Agreement for Trade in Services (
Arjan Lejour, Nico van Leeuwen
core  

Sitio web HTML5 CSS3 RWD

, 2014
El principal objetivo de este Proyecto Final de Carrera es conseguir que la empresa YOLANEVA consiga una nueva y mejor presencia en Internet.Para ello, se ha realizado una nueva página web dotándola de las herramientas SEO, tal y como puede observarse en www.yolaneva.com.
openaire   +2 more sources

Sex‐Specific Involvement of Gut Microbiota in Behavioral and Endocrine Responses to Chronic Predator Odor in Brandt's Voles

Integrative Zoology, EarlyView.
18 days of predator odor exposure altered gut microbiota, increased anxiety‐like behaviors, and elevated hypothalamic–pituitary–adrenal axis activity in Brandt's voles, with males showing behavioral habituation and females remaining sensitive. Cecal microbiota transplantation experiments confirmed that only female recipients of microbiota from predator‐
Chen Gu, Ruiping Xu, Baofa Yin, Ruiyong Wu, Youheng Wei, Dehua Wang, Wanhong Wei   +6 more
wiley   +1 more source