Results 151 to 160 of about 12,767 (235)

Participant recruitment, Pre-existing RWD access, Prospective RWD acquisition and secure storage -v3

D8.3-D8.7, reported in 5 deliverables, each one being an update of the previous one, aim to: (a) reflect the number of participants enrolled prospectively on a biannual basis until the end of the study and verify ethical RWD acquisition following informed consent and IRB approval; (b) document the amount of RWD reflective of our CoBraD Protocol ...
openaire   +1 more source

Applicability of academic real-world data research in the case studies of the HTx project to practical health technology assessment work. [PDF]

Front Pharmacol
Björvang C, Pontén J, Viberg A, Manca A, Salanti G, Siirtola P, García-Sáez G, Knies S, Delnoij D, Dawoud D, Elvidge J, Liu L, Németh B, Kaló Z.   +13 more
europepmc   +1 more source

Development and Release of the Munich UICC Staging Tool (MUST): Advancing UICC Staging in Real‐World Data With Insights From Pancreatic and Stomach Cancer

International Journal of Cancer, Volume 159, Issue 3, Page 757-767, 1 August 2026.
Accurate cancer staging is essential for cancer research and treatment evaluation. However, real‐world data often include incomplete or inconsistent UICC staging classifications. The presented Munich UICC Staging Tool (MUST) automates UICC stage derivation from TNM classifications and tumor characteristics, incorporating novel real‐world data rules to ...
Brigitte Kühnel, Sophie Schneiderbauer, Sebastian Lange, Dirk Wilhelm, Helmut Friess, Marcus Feith, Ursula Ehmer, Florian Bassermann, Julian W. Holch, Stefan M. Munker, Jens Neumann, Jens Werner, Hubert J. Stein, Theres Fey, Ulrich Mansmann, Hana Algül, Karin Berger‐Thürmel, H. Carlo Maurer, Daniel Nasseh   +18 more
wiley   +1 more source

R WE ready for reimbursement? A round-up of developments in real-world evidence relating to health technology assessment: part 25. [PDF]

J Comp Eff Res
Arora P, Ramagopalan SV.
europepmc   +1 more source

A cost‐effectiveness analysis of breast cancer treatment in certified versus non‐certified hospitals in Germany

International Journal of Cancer, Volume 159, Issue 1, Page 159-172, 1 July 2026.
What's New? This study is the first to quantify the cost‐effectiveness of breast cancer treatment in German Cancer Society‐certified hospitals using real‐world data from over 140,000 patients. Analysis on certification‐related costs and survival outcomes demonstrates that high‐quality multidisciplinary care at certified hospitals delivers substantial ...
Min‐Wai Lwin, Olaf Schoffer, Christoph Streissnig, Pauline Wimberger, Michael Gerken, Veronika Bierbaum, Christoph Bobeth, Martin Rößler, Patrik Dröge, Thomas Ruhnke, Christian Günster, Kees Kleihues‐van Tol, Theresa Link, Anton Scharl, Elisabeth C. Sturm‐Inwald, Karin Kast, Thomas Papathemelis, Olaf Ortmann, Monika Klinkhammer‐Schalke, Jochen Schmitt, Michael Schlander   +20 more
wiley   +1 more source

Methods Applied to Assess Real-World Effectiveness of Drugs: A Scoping Review. [PDF]

Pharmacol Res Perspect
von Osmanski BI, Petersen J, Petersen CT, Bentsen AH, Jimenez-Solem E, Ankarfeldt MZ.   +5 more
europepmc   +1 more source

Surveillance of Pharmaceutical Risk‐Mitigation Behavior: Applying and Comparing Statistical Process Control Methods Using Real World Data

Learning Health Systems, Volume 10, Issue 3, July 2026.
ABSTRACT Introduction Active post‐marketing surveillance of prescribing behavior of high‐risk drugs may provide early warning of unforeseen issues in a population, yet analysis approaches for surveillance using real‐world data are underdeveloped.
Harris Butler, John D. Rice, Nichole E. Carlson, Elaine H. Morrato   +3 more
wiley   +1 more source

Application of the toolbox and the repository to unCoVer RWD

Scientific report of its usability and joint publications Task 42 and Task 45 ...
openaire   +1 more source

A scoping review on using real-world data to evaluate the effectiveness of mHealth applications. [PDF]

NPJ Digit Med
Gehder S, Brückner S, Gilbert S, Goeldner M.   +3 more
europepmc   +1 more source

Dexmedetomidine Rapidly Relieves Stress‐Induced Hyperalgesia via Presynaptic α2‐Adrenergic Inhibition at Orbitofrontal–Insular Glutamatergic Synapses

MedComm, Volume 7, Issue 7, July 2026.
This study identified a maladaptive OFC–AIC glutamatergic circuit in stress‐induced hyperalgesia induction. This critical circuit provides an α2‐AR‐dependent braking target for dexmedetomidine to alleviate excessive glutamatergic transmission and hyperalgesia. ABSTRACT Dexmedetomidine (Dex), an α2‐adrenergic receptor (α2‐AR) agonist, is widely used for
Hui Rong, Yang‐Xun Zhang, Huijie Zhu, Yinyao Li, Yunfan Hou, Yun‐Yong Xie, Lu‐Yao Li, Bei‐Bei Zhang, Shu‐Tao Xie, Wei Zhang, Qi‐Peng Zhang, Xiao‐Yang Zhang, Jing‐Ning Zhu, Xiaoping Gu, Zhengliang Ma   +14 more
wiley   +1 more source