Results 21 to 30 of about 27,021 (267)

ICH Reflection paper on proposed international harmonization of real-world evidence terminology and convergence of general principles regarding planning and reporting of studies using real-world data, with a focus on effectiveness of drugs

open access: yesРеальная клиническая практика: данные и доказательства, 2023
Real-world data and real-world evidence play an increasingly important role in clinical research and healthcare decisionmaking. To use data and generate robust evidence effectively, they must be clearly defined and structured, semantically compatible and
K. S. Radaeva, R. R. Niyazov
doaj   +1 more source

Analyzing FDA's approaches to using electronic health record and medical claims data to support regulatory decision making

open access: yesРеальная клиническая практика: данные и доказательства, 2023
In 2021, the U.S. Food and Drug Administration (FDA) issued draft guidance on the use of electronic health records and medical claims data for regulatory decisions.
Ksenia S. Radaeva, M. V. Pchelintsev
doaj   +1 more source

Snapshot: Trial Types in Precision Medicine. [PDF]

open access: yes, 2020
Integrating precision diagnostics into personalized treatments requires understanding how biomarkers relate to clinical outcomes. Various clinical data collection methods exist, each with strengths and weaknesses. Interventional data are high quality but
Bergan, Raymond   +5 more
core  

Machine learning capabilities for the diagnosis of orphan diseases

open access: yesРеальная клиническая практика: данные и доказательства, 2023
Rare or orphan diseases belong to one of the most severe groups of diseases. At the same time, early and accurate diagnosis of such diseases is a serious problem for general practitioners, pediatricians and therapists.
N. Y. Dmitrieva
doaj   +1 more source

HST/FOS Eclipse Observations of the Nova-like Cataclysmic Variable UX Ursae Majoris [PDF]

open access: yes, 1998
[abridged abstract] We present and analyze Hubble Space Telescope observations of the eclipsing nova-like cataclysmic variable UX UMa obtained with the Faint Object Spectrograph.
Buser R.   +24 more
core   +2 more sources

The mass and radius of the M-dwarf in the short period eclipsing binary RR Caeli [PDF]

open access: yes, 2007
We present new photometry and spectroscopy of the eclipsing white dwarf - M-dwarf binary star RR Cae. We use timings of the primary eclipse from white-light photo-electric photometry to derive a new ephemeris for the eclipses. We find no evidence for any
Maxted, P.F.L.   +4 more
core   +6 more sources

Role of RWD / RWE in health technology assessment

open access: yesReal-World Data & Evidence, 2023
For many reasons randomized clinical trials today can»t cope with the tasks set by modern health care, which was clearly demonstrated by the COVID-19 pandemic. This gave new impetus to the development of the RWD / RWE. It became obviously that in cases of impossibility, unethical and other reasons, new methods for obtaining high-quality evidence may be
V. G. Borovskaya, A. A. Kurylev
openaire   +2 more sources

D8.5 Participant recruitment, Preexisting RWD access, Prospective RWD acquisition and secure storage –v3

open access: yes, 2023
The Multidisciplinary Expert System for the Assessment & Management of Complex Brain Disorders (MESCoBraD) project integrates a group of professionals with inter-expertise and where a wide number of different fields of research interact. Four centres from the collaborative effort, have agreed to incorporate participant data, ranging from clinical ...
openaire   +1 more source

RWD based IDS for MANET

open access: yesInternational Journal of Computer Applications, 2015
Mobile Ad-Hoc network (MANET) is a temporary infrastructure less network. This network is formed by combining some set of wireless mobile hosts [1] [5]. The host is called as a node which dynamically establishes their own network. Intrusion detection in MANETs, however, is challenging for a number of reasons.
Sachin Bojewar, Kavita Varule
openaire   +1 more source

The role of real world data and real world evidence in health technology assessment

open access: yesФармакоэкономика, 2022
Real world data (RWD) and real world evidence (RWE) is one of the most rapidly developing areas in the modern health care systems, which is caused by the development of technologies for both collecting and analyzing data, the emergence of new data ...
E. A. Novoderezhkina, S. К. Zyryanov
doaj   +1 more source

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