Results 51 to 60 of about 27,021 (267)

A 3D Astrocyte Microenvironment Model Enables Rapid Ca2+‐Resolved Analysis and Therapeutic Modulation of Oxidative Neuroinflammation

open access: yesAdvanced Healthcare Materials, EarlyView.
This work presents ARC‐3D, a soft 3D model that recreates how brain support cells, called astrocytes, react to oxidative stress. The system visualizes rapid calcium changes and inflammatory signals, and shows how the drug KDS12025 can protect cells from damage. ARC‐3D offers a simple, reliable way to study early drivers of brain inflammation.
Ju‐Kang Kim   +6 more
wiley   +1 more source

GCRT J1745-3009 as a Transient White Dwarf Pulsar

open access: yes, 2005
A transient radio source in the direction of the Galactic Center, GCRT J1745-3009, exhibited 5 peculiar consecutive outbursts at 0.33 GHz with a period of 77.13 minutes and a duration of ~10 minutes for each outburst.
Bing Zhang   +7 more
core   +1 more source

The boundary layer of VW Hyi in quiescence [PDF]

open access: yes, 2004
In this letter, we suggest that the missing boundary layer luminosity of dwarf novae in quiescence is released mainly in the ultraviolet (UV) as the second component commonly identified in the far ultraviolet (FUV) as the "accretion belt".
Belloni   +29 more
core   +2 more sources

Dynamics of the Mammalian Placental Metabolome in Placentogenesis and Embryonic Development

open access: yesAdvanced Science, EarlyView.
This study identifies three metabolic stages (E8.5, E9.5–10.5, E11.5–14.5) and two transition periods (E8.5–9.5, E10.5–11.5) in mouse placental development. NAD(H) emerges as a key dynamic metabolite that enhances embryonic growth through accelerated segmentation and increased proliferation of mouse embryonic stem cell (mESC)‐induced presomitic ...
Gang Chen   +11 more
wiley   +1 more source

Exploring the influential factors of roadway departure crashes on rural two-lane highways with logit model and association rules mining

open access: yesInternational Journal of Transportation Science and Technology, 2021
Roadway departure (RwD) crashes are a major contributor of rural two-lane (R2L) highway crashes and fatalities. For targeted reduction of crashes and fatalities due to roadway departure, a thorough understanding of factors associated with RwD crashes is ...
M. Ashifur Rahman   +3 more
doaj   +1 more source

An outburst of the magnetic cataclysmic variable XY Arietis observed with RXTE

open access: yes, 1997
We report the first observed outburst of the magnetic cataclysmic variable XY Ari. X-ray observations show a flux increase by an order of magnitude the day after the first signs of outburst.
Beardmore, A. P.   +2 more
core   +2 more sources

Comprehensive Profiling of N6‐methyladnosine (m6A) Readouts Reveals Novel m6A Readers That Regulate Human Embryonic Stem Cell Differentiation

open access: yesAdvanced Science, EarlyView.
This research deciphers the m6A transcriptome by profiling its sites and functional readout effects: from mRNA stability, translation to alternative splicing, across five different cell types. Machine learning model identifies novel m6A‐binding proteins DDX6 and FXR2 and novel m6A reader proteins FUBP3 and L1TD1.
Zhou Huang   +11 more
wiley   +1 more source

Expert survey on real‐world data utilization and real‐world evidence generation for regulatory decision‐making in drug lifecycle in Korea

open access: yesClinical and Translational Science
As the importance of utilizing real‐world data (RWD)/real‐world evidence (RWE) for supporting regulatory scientific decision‐making continues to grow, experiences and inputs from experts become crucial for developing a systematic and practice‐oriented ...
Hankil Lee   +4 more
doaj   +1 more source

Grade 4 learners with reading and writing difficulties in Mauritius: Oral reading and spelling characteristics

open access: yesSouth African Journal of Childhood Education, 2023
Background: Learners with reading and writing difficulties (RWD) are accommodated in Mauritian government schools without formal curriculum adjustment and teacher support. Little is known about their RWD.
Sattiavany Veerabudren   +4 more
doaj   +1 more source

Antenna Design for Semi-Passive UHF RFID Transponder with Energy Harvester [PDF]

open access: yes, 2015
A novel microstrip antenna which is dedicated to UHF semi-passive RFID transponders with an energy harvester is presented in this paper. The antenna structure designed and simulated by using Mentor Graphics HyperLynx 3D EM software is described in ...
Jankowski-Mihulowicz, P.   +2 more
core   +2 more sources

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