Results 81 to 90 of about 27,021 (267)

The emission-line pulse pattern in the intermediate polar RX J0558 [PDF]

, 1999
We observed the intermediate polar RX J0558+53 with the 4.2m WHT and find in the pulsed emission lines, a ``corkscrew'' pattern, which indicates a two-pole white dwarf accretion.
Allan, Ashoka, Emilios T. Harlaftis, Ferrario, Frank, Ghosh, Haberl, Haberl, Hamada, Hameury, Harlaftis, Harlaftis, Harlaftis, Harlaftis, Harlaftis, Haswell, Hellier, Hellier, Hellier, Hellier, Hellier, Hellier, Horne, Horne, Horne, Ishida, Kamata, Keith Horne, King, Lamb, Lubow, Mukai, Norton, Oke, Patterson, Penning, Piirola, Robinson, Rosen, Scargle, Schachter, Schwope, Seaton, Skillman, Smith, Steeghs, Still, Walker, Warner, Welsh, Wynn   +50 more
core   +3 more sources

Respiratory‐Limbic Coupling via a Thalamic Circuit Alleviates Anxiety

Advanced Science, EarlyView.
This study delineates a conserved preBötCGlu→PVT→CeA circuit that gates anxiety and respiration. Activation of this circuit is anxiolytic and respiratory‐stabilizing, while its inhibition has the opposite effect. Mechanistically, PVT exerts its anxiolytic action via a disinhibitory microcircuit: its inputs preferentially target CeL GABAergic neurons ...
Shangyu Bi, Xiaoyi Wang, Huichun Luo, Ziteng Yue, Tianjiao Deng, Yuhang Liu, Xinxin Chen, Jianxu Zhao, Luo Shi, Ning Ma, Lingyan Mao, Jing Ding, Jiwen Xu, Ti‐Fei Yuan, Sheng Wang, Fang Yuan   +15 more
wiley   +1 more source

WebCat: RWD, dealing with navigation

Mosaic, 2013
El WebCat es el punto de encuentro entre profesionales del sector web (desarrolladores, diseñadores, emprendedores, etc.) abierto a cualquier persona interesada en esta parcela. Dentro de WebCat se abordan asuntos diversos, tanto de forma introductoria como especializada, mediante breves exposiciones de no más de quince minutos con el objetivo de ...
openaire   +1 more source

Targeted H2S Delivery System Attenuates Blood‐Spinal Cord Barrier Disruption after Spinal Cord Injury by Reshaping the Ferritinophagy Pathway

Advanced Science, EarlyView.
The αvβ3‐mediated SPRC@MPDA‐RGD targets broken endothelial cells and controllably releases SPRC. CSE is then activated to produce endogenous H2S, which inhibits ferritinophagy. In brief, H2S inhibits autophagy by activating the PI3K/Akt/mTOR pathway, thereby suppressing the ferroptosis process mediated by NCOA4, and ultimately promoting the ...
Zhiheng Chen, Xinkai Pu, Ruiyang Li, Yuezhou Wu, Qirong Zhou, Jian Wang, Yuxuan Qian, Fengjie Lu, Jian‐Yuan Zhao, Zhida Su, Jiacan Su, Xiaofeng Lian   +11 more
wiley   +1 more source

Ionization structure of hot components in symbiotic binaries during active phases

, 2012
During active phases of symbiotic binaries, an optically thick medium in the form of a flared disk develops around their hot stars. During quiescent phases, this structure is not evident.
Carikova, Zuzana, Skopal, Augustin
core   +1 more source

A white dwarf merger as progenitor of the anomalous X-ray pulsar 4U 0142+61? [PDF]

, 2013
It has been recently proposed that massive fast-rotating highly-magnetized white dwarfs could describe the observational properties of some of Soft Gamma-Ray Repeaters (SGRs) and Anomalous X-Ray Pulsars (AXPs).
Aguilar, P. Loren, Berro, E. Garcia, Boshkayev, K., Izzo, L., Kulebi, B., Rueda, J. A., Ruffini, R., Siguan, G. Aznar   +7 more
core   +3 more sources

Nature‐Inspired Surface Modification Strategy Reverses the Autophagic Flux Impairment of Mitochondrial Transplantation for Attenuating Ischemic Strokes

Advanced Science, EarlyView.
The functionalized starch modifies the mitochondrial surface and encapsulates resveratrol into the cavity of helices, facilitating a novel mitochondrial transplantation platform (MLSR). Upon internalization in recipient cells, MLSR triggers mitophagy and maintains positive autophagic flux through RIP1/RIP3 pathway inhibition.
Nisha Wang, Qiyang Ding, Lei Shi, Ji Xia, Shuyue Zhang, Chenxin Jian, Yixiao Yan, Xiuhua Luo, Jiarui Wang, Ming Cheng, Yiqiong Jia, Hao Tian, Wei Gao   +12 more
wiley   +1 more source

A comparative study of clinical trial and real-world data in patients with diabetic kidney disease

Scientific Reports
A growing body of research is focusing on real-world data (RWD) to supplement or replace randomized controlled trials (RCTs). However, due to the disparities in data generation mechanisms, differences are likely and necessitate scrutiny to validate the ...
Samu Kurki, Viivi Halla-aho, Manuel Haussmann, Harri Lähdesmäki, Jussi V. Leinonen, Miika Koskinen   +5 more
doaj   +1 more source

Real-World Data and Real-World Evidence in Healthcare in the United States and Europe Union

Bioengineering
The use of real-world data (RWD) for healthcare decision-making is complicated by concerns regarding whether RWD is fit-for-purpose or is of sufficient validity to support the creation of credible RWE.
Kelly H. Zou, Marc L. Berger
doaj   +1 more source

A Self-Occulting Accretion Disk in the SW Sex Star DW UMa [PDF]

, 2000
We present the ultraviolet spectrum of the SW Sex star and nova-like variable DW UMa in an optical low state, as observed with the Space Telescope Imaging Spectrograph on board the Hubble Space Telescope (HST).
Christian Knigge, D. W. Hoard, Dhillon V. S., Dhillon V. S., Dhillon V. S., Horne K., Knox S. Long, Marsh T. R., Panei J. A., Paula Szkody, Rutten R. G. M., Smak J., V. S. Dhillon   +12 more
core   +2 more sources