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Expression and localization of RLF/ INSL3 receptor RXFP2 in boar testes

IJAE : Italian Journal of Anatomy and Embryology : 118, 1 Supplement, 2013
This study investigated the possibility of the presence of specific receptor for relaxin-like factor (RLF)/insulin-like peptide 3 (INSL3) in boar testes. While RLF/INSL3 was produced by Leydig cells in the boar testis, its own receptor RXFP2 was expressed mainly in meiotic and post-meiotic germ cells, but not in Leydig cells, suggesting the existence ...
Kohsaka, Tetsuya +4 more
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Perinatal Zearalenone Exposure Affects RXFP1, RXFP2, and Morphoregulatory Gene Expression in the Neonatal Porcine Uterus

Annals of the New York Academy of Sciences, 2009
The mycotoxin zearalenone (ZEA) is a selective estrogen receptor modulator that can contaminate cereal feeds and lead to reproductive disorders. To determine effects of perinatal ZEA exposure on uterine expression of genes associated with endometrial development in the neonatal gilt, pregnant sows were fed ZEA (1500 μg ZEA/kg of feed/day) or vehicle ...
Joseph C, Chen +5 more
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Genetic Association of RXFP2 T222P Variant With Cryptorchidism: A Meta‐Analytic Study

Andrology
ABSTRACT Background The RXFP2 receptor plays a key role in testicular descent, mediating the action of relaxin on gubernaculum development. The T222P polymorphism in the RXFP2 gene has previously been investigated in relation to
Jacek Kabziński, Jerzy Niedzielski, Ireneusz Majsterek +2 more
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Constitutive activity of human RXFP2