Results 71 to 80 of about 863 (134)

Distinct but overlapping binding sites of agonist and antagonist at the relaxin family peptide 3 (RXFP3) receptor [PDF]

, 2018
The relaxin-3 neuropeptide activates the relaxin family peptide 3 (RXFP3) receptor to modulate stress, appetite and cognition. RXFP3 shows promise as a target for treating neurological disorders, but realization of its clinical potential requires ...
Kaas, Quentin, Hossain, Mohammed Akhter, Rosengren, K. Johan, Scott, Daniel James, Wong, Lilian L. L., Bathgate, Ross A. D.   +5 more
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Relaxin-3/RXFP3 system in alcohol self-administration and relapse

, 2016
© 2016 Dr. Hanna Erika KastmanAlcoholism is a chronic relapsing disorder, accounting for 10% of disability-adjusted life years lost in industrialized countries.
Kastman, Hanna Erika
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Relaxin-3/RXFP3 signalling in mouse hypothalamus: no effect of RXFP3 activation on corticosterone, despite reduced presynaptic excitatory input onto paraventricular CRH neurons in vitro

, 2017
Relaxin-3/RXFP3 signalling is proposed to be involved in the neuromodulatory control of arousal- and stress-related neural circuits. Furthermore, previous studies in rats have led to the proposal that relaxin-3/RXFP3 signalling is associated with ...
JS Bains (14876695), DV Baimoukhametova (14876692), AL Gundlach (14448708), Craig Smith (13065255), C Zhang (2567170)   +4 more
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Central relaxin-3 receptor (RXFP3) activation impairs social recognition and modulates ERK-phosphorylation in specific GABAergic amygdala neurons [PDF]

, 2019
This is a pre-print of an article published in Brain Structure and Function. The final authenticated version is available online at: https://doi.org/10.1007/s00429-018-1763-5In mammals, the extended amygdala is a neural hub for social and emotional ...
Sánchez-Pérez, Ana María, Albert Gasco, Hector, Gundlach, Andrew Lawrence, Gundlach, Andrew L., García Díaz, Cristina, Olucha-Bordonau, Francisco E, Sánchez-Sarasúa, Sandra, Ma, Sherie   +7 more
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Non-invasive diagnosis of vulvar dysplasia using cervical methylation markers—a case control study

BMC Medicine
Background Diagnostic screenings for vulvar squamous intraepithelial lesions (VSIL) are limited and without information on disease trends. A panel of six methylation markers (ASTN1, DLX1, ITGA4, RXFP3, SOX17, ZNF671; GynTect® assay) has shown promise in ...
Sabeth Becker, Lena Dübbel, Dana Behrens, Kristin Knoll, Juliane Hippe, Karin Loser, Eduard Malik, Meike Schild-Suhren   +7 more
doaj   +1 more source

The role of relaxin-3/RXFP3 system in hyperphagia

, 2020
Les troubles alimentaires sont souvent déclenchés par le stress et sont plus fréquents chez les femmes que chez les hommes. Les premiers symptômes apparaissent au début de l'adolescence, mais le fondement biologique des différences selon le sexe est ...
De Avila Dal'Bo, Camila
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Design, synthesis, and characterization of a single-chain peptide antagonist for the relaxin-3 receptor RXFP3

, 2011
Relaxin-3 is a two-chain disulfide-rich peptide that is the ancestral member of the relaxin peptide family and, together with its G protein-coupled receptor RXFP3, is highly expressed in the brain. Strong evolutionary conservation of relaxin-3 suggests a
Clark, Richard J., Shabanpoor, Fazel, Shabanpoor, Fazel,, Andrew L. Gundlach, Bathgate, Ross,, Mohammed Akhter Hossain, Ross A. D. Bathgate, Haugaard-Kedström, Linda M.,, Rosengren, K. Johan,, Richard J. Clark, Fazel Shabanpoor, John D. Wade, David J. Craik, Hossain, Mohammed Akhter, Rosengren, K. Johan, Bathgate, Ross A. D., Haugaard-Kedström, Linda M., Philip J. Ryan, Linda M. Haugaard-Kedström, K. Johan Rosengren, Hossain, Mohammed Akhter,, Kedström, Linda Maria Haugaard, Craik, David J., Wade, John,, Gundlach, Andrew L., Ryan, Philip,, Wade, John D., Clark, Richard,, Gundlach, Andrew,, Craik, David,, Ryan, Philip J.   +30 more
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Design, Synthesis, and Characterization of a Single-Chain Peptide Antagonist for the Relaxin-3 Receptor RXFP3

, 2016
Relaxin-3 is a two-chain disulfide-rich peptide that is the ancestral member of the relaxin peptide family and, together with its G protein-coupled receptor RXFP3, is highly expressed in the brain. Strong evolutionary conservation of relaxin-3 suggests a
Linda M. Haugaard-Kedström (1656241), Fazel Shabanpoor (495873), David J. Craik (13753), K. Johan Rosengren (1346457), Mohammed Akhter Hossain (495874), John D. Wade (488630), Richard J. Clark (468092), Andrew L. Gundlach (145809), Philip J. Ryan (2213596), Ross A. D. Bathgate (145814)   +9 more
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Validation of Relaxin-3 Receptor RXFP3 Antibodies in Chicken Reproductive Tissue and Presence of RXFP3 Receptors in the Chicken Brain

Faculty Advisor: Kahina BoukherroubThis research was supported by the Undergraduate Research Opportunities Program (UROP). Research was also partially funded by the CFANS Research Apprenticeship Program.Yang, Evelyn. (2025).
Yang, Evelyn
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Rôle du système relaxine-3/RXFP3 dans les contrôles descendants de la douleur chez la souris. [PDF]

, 2019
Pain is a complex biological phenomenon that is beneficial and necessary for our survival, warning of changes and hazards in the environment that compromise optimal function.
Guerreiro Covita, João
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