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Purinergic agonists increase [Ca²⁺]_i in rat conjunctival goblet cells through ryanodine receptor type 3.

Am J Physiol Cell Physiol
Fjaervoll HK, Fjaervoll KA, Yang M, Reiten OK, Bair J, Lee C, Utheim TP, Dartt D.   +7 more
europepmc   +1 more source

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Ryanodine receptors

Cell Calcium, 2005
RyRs are large homotetrameric proteins that are approximately 4/5 cytoplasmic and approximately 1/5 transmembrane and luminal in mass. Mutations in RyRs produce human disease and many of these disease-causing mutations are in the cytoplasmic domains. To elucidate the mechanisms of a disease and to develop interventions, it is crucial to determine how ...
Stephan Lehnart, Xander Wehrens, Andrew Marks   +2 more
  +6 more sources

Ryanodine Receptor

Encyclopedia of Molecular Pharmacology, 2008
Takashi Murayama, Nagomi Kurebayashi, Yasuo Ogawa   +2 more
openaire   +2 more sources

Ryanodine Receptor

2012
Pedro Tauler Riera, Maurizio Volterrani, Ferdinando Iellamo, Francesco Fallo, Andrea Ermolao, William J. Kraemer, Nicholas A. Ratamess, Avery Faigenbaum, Andrew Philp, Keith Baar   +9 more
semanticscholar   +4 more sources

Ryanodine receptor channelopathies

Biochemical and Biophysical Research Communications, 2004
Ryanodine receptors (RyR) are the Ca2+ release channels of sarcoplasmic reticulum that provide the majority of the [Ca2+] necessary to induce contraction of cardiac and skeletal muscle cells. In their cellular environment, RyRs are exquisitely regulated by a variety of cytosolic factors and accessory proteins so that their output signal (Ca2+) induces ...
Nancy A, Benkusky, Emily F, Farrell, Héctor H, Valdivia   +2 more
openaire   +2 more sources

Ryanodine receptor type 3 why another ryanodine receptor isoform

Frontiers in Bioscience, 2003
The family of ryanodine receptor (RyR) genes encodes three highly related Ca2+ release channels: RyR1, RyR2 and RyR3. Until about 10 years ago, RyRs were essentially known only for being the Ca2+ release channels of the sarcoplasmic reticulum of striated muscles, because of the high levels of expression of the RyR1 and RyR2 isoforms in skeletal and ...
openaire   +3 more sources

Ryanodine Receptor as Insecticide Target

Current Pharmaceutical Design, 2022
: The ryanodine receptor (RyR) is one of the primary targets of commercial insecticides. The diamide insecticide family, including flubendiamide, chlorantraniliprole, cyantraniliprole, etc., targets insect RyRs and can be used to control a wide range of destructive agricultural pests.
Samurkas, Arthur, Yao, Li, Hadiatullah, Hadiatullah, Ma, Ruifang, Xie, Yunxuan, Sundarraj, Rajamanikandan, Zuilhof, Han, Yuchi, Zhiguang   +7 more
openaire   +2 more sources

Ryanodine Receptor

British Journal of Pharmacology, 2006
S P H Alexander, A Mathie, J A Peters
  +4 more sources