Results 161 to 170 of about 28,867 (291)

The human cardiac muscle ryanodine receptor-calcium release channel: identification, primary structure and topological analysis [PDF]

, 1996
Richard Tunwell, Colin Wickenden, Bénédicte Bertrand, Valery I. Shevchenko, Martina B. WALSH, Paul D. Allen, F. Anthony Lai   +6 more
openalex   +1 more source

An age‐associated decline in the role of the sarcoplasmic reticulum and associated calcium‐handling proteins sets the pace for sinoatrial node function

The Journal of Physiology, EarlyView.
Abstract figure legend Stable, responsive pacemaking in the sinoatrial node is driven by the activity of the funny current (membrane clock), interplay of calcium cycling and release from the sarcoendoplasmic reticulum with depolarising sodium‐calcium exchange current (calcium clock). With increasing age, key proteins associated with calcium cycling are
Sandra A. Jones, Fiona S. Godbeer, Matthew K. Lancaster   +2 more
wiley   +1 more source

Distinct roles for the ryanodine and IP3 receptor intracellular calcium release channels in memory formation using a single-trial discrimination avoidance task for young chicks

, 2017
Kathryn Baker
  +4 more sources

Abnormal Interactions of Calsequestrin With the Ryanodine Receptor Calcium Release Channel Complex Linked to Exercise-Induced Sudden Cardiac Death [PDF]

, 2006
Dmitry Terentyev, Alessandra Nori, Massimo Santoro, Serge Viatchenko‐Karpinski, Zuzana Kubalová, Inna Györke, Radmila Terentyeva, Srikanth Vedamoorthyrao, Nico A. Blom, Giorgia Valle, Carlo Napolitano, Simon C. Williams, Pompeo Volpe, Silvia G. Priori, Sándor Györke   +14 more
openalex   +1 more source

Oleuropein‐based olive leaf extract enhances muscle mitochondrial bioenergetics response to moderate – but not maximal – intensity exercise in humans

The Journal of Physiology, EarlyView.
Abstract figure legend In a double‐blind, crossover study, we observed that olive leaf extract (OLE) intake combined with a single session of moderate‐intensity continuous exercise (MICE) significantly enhanced skeletal muscle mitochondrial bioenergetics, whereas this effect was milder when OLE was combined with sprint interval exercise (SIE ...
Clément Lanfranchi, Alba Moreno‐Asso, Astrid M. H. Horstman, Sara Mistro, Eugenia Migliavacca, Ornella Cominetti, Jens Stolte, Sylviane Métairon, Aurélie Hermant, Ane Laura Pedersen, Loïc Dayon, Umberto De Marchi, Jérôme N. Feige, Nadège Zanou, Nicolas Place   +14 more
wiley   +1 more source

Harántcsíkolt izom SR kalcium csatornájának modulációja egészséges és kóros körülmények között = Modulation of the SR calcium channels of striated muscle in health and disease [PDF]

, 2006
Az izom összehúzódás kiváltásában centrális szerepet játszó elektromechanikai csatolás kulcs-molekuláit tanulmányoztuk. Megállapítottuk, hogy a gadolinium ion mind a cisz mind a transz oldalról hasonlóan gátolja a csatornát (Ki=5,38+-0,63microM és Ki=5 ...
Jóna, István, Körtvély, Ágnes, Lukács, Balázs, Szegedi, Csaba, Sárközi, Sándor   +4 more
core  

Selenoprotein N is required for ryanodine receptor calcium release channel activity in human and zebrafish muscle

, 2008
Michael J. Jurynec, Ruohong Xia, John J. Mackrill, Derrick Gunther, Thomas Crawford, Kevin M. Flanigan, Jonathan J. Abramson, Michael Howard, David J. Grunwald   +8 more
openalex   +2 more sources

Mitochondrial Homeostasis in Pancreatic β Cell Function: Mechanisms and Therapeutic Targets for Diabetes

Journal of Diabetes, Volume 18, Issue 5, May 2026.
This review highlights mitochondrial dysfunction as a central driver of pancreatic β cell failure in diabetes, caused by disrupted mitochondrial quality control (MQC), oxidative stress, and impaired organelle communication. Emerging therapies, such as DRAK2 inhibitors and metabolic reprogramming agents, show promise in restoring β cell function by ...
Ruihan Li, Bingqian Zhang, Yuxin Zhang, Yang Yang, Yuting Lu, Jingya Li   +5 more
wiley   +1 more source

UNC45B Reduction With Aging: A Myofiber‐Intrinsic Promoting Factor for Sarcopenia

Aging Cell, Volume 25, Issue 5, May 2026.
Aging reduces Unc45b expression in fast‐twitch muscle, concomitant with reduction in muscle contractile capacity and muscle mass in mice. Unc45b deficiency initially reduces depolarization‐induced force, followed by a decline in fast‐twitch muscle mass in adult mice.
Taiga Mishima, Taiga Nagamune, Saori Tada, Daiki Watanabe, Nao Tokuda, Takashi Yamada, Akiko Hashimoto‐Hachiya, Sayaka Higo‐Yamamoto, Kohei Kido, Noriyuki Nagaoka, Aoi Ikedo, Yuuki Imai, Ryo Fujita, Seiya Mizuno, Satoru Takahashi, Katsutaka Oishi, Satoru Ato, Riki Ogasawara   +17 more
wiley   +1 more source

Connexin43 Deficiency Leads to Ventricular Arrhythmias by Reprogramming Proline Metabolism

Advanced Science, Volume 13, Issue 19, 2 April 2026.
The study demonstrated that connexin43 (Cx43) knockout caused arrhythmic phenotype and decreased proline content in vitro and in vivo. Mechanistically, Cx43 interacts with the amino acid transporter SNAT2 (sodium‐dependent neutral amino acid transporter), and its deficiency disrupts proline transport and metabolism.
Hangying Ying, Hangping Fan, Yunhe Wang, Ruhong Jiang, Dongsheng Cai, Hui Cheng, Hao Wang, Chenyang Jiang, Ping Liang   +8 more
wiley   +1 more source