Results 161 to 170 of about 2,684,234 (246)

Gβγ subunit activation of KV7 and BKCa channels underlies calcitonin gene‐related peptide vasorelaxation in myogenic rat coronary resistance arteries

British Journal of Pharmacology, Volume 183, Issue 16, Page 5018-5032, August 2026.
Abstract Background and Purpose CGRP is a potent, clinically relevant coronary vasodilator known to play a role in cardioprotection. Here, we investigated the precise intracellular signalling pathways leading to vasodilation in small coronary arteries.
Lucy A. Donovan, JinHeng Lin, Milind Khashu, Christopher J. Garland, Kim A. Dora   +4 more
wiley   +1 more source

Sperm Motility Is Modulated by F₄-Neuroprostane via the Involvement of Ryanodine Receptors. [PDF]

Int J Mol Sci
Signorini C, Moretti E, Liguori L, Marcucci C, Durand T, Galano JM, Oger C, Collodel G.   +7 more
europepmc   +1 more source

Function and expression of ryanodine receptors and inositol 1,4,5‐trisphosphate receptors in smooth muscle cells of murine feed arteries and arterioles

Journal of Physiology, 2012
E. B. Westcott, Erica L. Goodwin, S. Segal, W. Jackson   +3 more
semanticscholar   +1 more source

Structural basis for diamide modulation of ryanodine receptor

Nature Chemical Biology, 2020
R. Ma, O. Haji-Ghassemi, D. Ma, Heng Jiang, Lianyun Lin, Li Yao, A. Samurkas, Yuxin Li, Yiwen Wang, P. Cao, Shian Wu, Yan Zhang, T. Murayama, B. Moussian, F. van Petegem, Z. Yuchi   +15 more
semanticscholar   +1 more source

Sparks of life: Enabling multi‐scale investigations of pro‐arrhythmic calcium‐handling abnormalities

The Journal of Physiology, EarlyView.
Melania Buonocunto, Jordi Heijman
wiley   +1 more source

The interplay between pulsatility, sympathetic regulation and renal physiology: Implications for left ventricular assist devices

Experimental Physiology, Volume 111, Issue 8, Page 3514-3524, 1 August 2026.
Abstract Left ventricular assist devices have gained traction both as a bridge therapy and as a destination therapy in the management of heart failure. Many of these devices reinstate blood flow in a continuous manner as opposed to the pulsatile flow present in normal physiology.
Tania Warnakulasuriya, Zaid Bahi, Rohit Ramchandra   +2 more
wiley   +1 more source

A new stress test for ryanodine receptors. [PDF]

J Gen Physiol
Short B.
europepmc   +1 more source

Mechanisms underlying gastric antral slow waves – a human perspective

The Journal of Physiology, EarlyView.
Dirk F. van Helden
wiley   +1 more source

CaV1.2 dynamics in native male arterial myocytes

The Journal of Physiology, Volume 604, Issue 15, Page 6302-6323, 1 August 2026.
Abstract figure legend Proposed model of microtubule‐dependent CaV1.2 reorganization in vascular disease. Schematic illustration of microtubule‐mediated delivery and stabilization of CaV1.2 channels into enlarged plasma membrane clusters in response to Ang II or hyperglycaemia, promoting cooperative gating and enhanced Ca2+ influx. Abstract L‐type CaV1.
Miguel Martin‐Aragon Baudel, Hannah Voorhees, Arsalan U. Syed, Maryann K. Ferrara, Mary Horne, Johannes W. Hell, Luis F. Santana, Rose E. Dixon, Madeline Nieves‐Cintron, Manuel F. Navedo   +9 more
wiley   +1 more source

Pharmacology, Medicinal Chemistry, and Therapeutic Potential of Imidazoline Receptor Ligands

ChemMedChem, Volume 21, Issue 13, 14 July 2026.
Building on the excellent review article by Dardonville and Rozas (2004), this paper summarizes the most representative ligands of imidazoline receptors (IR; I1, I2, and I3) and updates their pharmacological profiles. Although not exhaustive, it provides a solid starting point for understanding the significance of I2 IRs as promising therapeutic ...
Maria‐Eleni Kouridaki, Mercè Pallàs, Carmen Escolano   +2 more
wiley   +1 more source