Results 141 to 150 of about 2,684,234 (246)

Skeletal Ryanodine Receptors Are Involved in Impaired Myogenic Differentiation in Duchenne Muscular Dystrophy Patients. [PDF]

Int J Mol Sci, 2021
Meyer P, Notarnicola C, Meli AC, Matecki S, Hugon G, Salvador J, Khalil M, Féasson L, Cances C, Cottalorda J, Desguerre I, Cuisset JM, Sabouraud P, Lacampagne A, Chevassus H, Rivier F, Carnac G.   +16 more
europepmc   +1 more source

Purification of Recombinant Wild Type and Mutant Ryanodine Receptors Expressed in HEK293 Cells. [PDF]

Bio Protoc, 2021
Hu Y, Iyer KA, Nayak AR, Kurebayashi N, Murayama T, Samsó M.   +5 more
europepmc   +1 more source

Bcl-2 binds to and inhibits ryanodine receptors

Journal of Cell Science, 2014
T. Vervliet, E. Decrock, J. Molgó, V. Sorrentino, L. Missiaen, L. Leybaert, H. de Smedt, N. N. Kasri, J. Parys, G. Bultynck   +9 more
semanticscholar   +1 more source

Testicular SIRT1 Loss Reveals an Aging‐Like Proteomic Landscape and Precipitates Reproductive Deterioration

Andrology, Volume 14, Issue 6, Page 1579-1589, September 2026.
ABSTRACT Background Advanced paternal age is associated with reduced male fertility and testicular dysfunction. Among the molecular regulators involved in aging, SIRT1, a NAD+‐dependent deacetylase, plays a pivotal role in maintaining oxidative balance and cellular homeostasis.
María Iniesta‐Cuerda, Jiřina Havránková, Hedvika Řimnáčová, Jiří Moravec, František Liška, Martin Knytl, Milena Králíčková, Jan Nevoral   +7 more
wiley   +1 more source

Ryanodine Receptors: A Potential Treatment Target in Various Neurodegenerative Disease. [PDF]

Cell Mol Neurobiol, 2021
Sun L, Wei H.
europepmc   +1 more source

ADAMTS4 mediates LPS‐induced cardiac injury and myocardial fibrosis through proteolytic cleavage of TSP1

Clinical and Translational Medicine, Volume 16, Issue 8, August 2026.
• ADAMTS4 is induced primarily in cardiac fibroblasts during sepsis. • ADAMTS4 cleaves TSP1 at the 236–246 aa functional region. • TSP1 cleavage activates TGF‐β/Smad and NF‐κB signalling in fibroblasts. • Targeting ADAMTS4 reduces fibroblast activation and cardiac fibrosis.
Zhe‐Wei Zhang, Shi‐Yan Wan, Wen Li, Xiao Lu, Rong Chen, Xin Xing, Wei Lai, Shu‐Yang Sheng, M. M. Mosebetsi, Qing‐Tao Meng, Zi‐Long Lu, Di Fan, Wan‐Li Jiang   +12 more
wiley   +1 more source

Cardiomyocyte Na⁺ and Ca²⁺ mishandling drives vicious cycle involving CaMKII, ROS, and ryanodine receptors. [PDF]

Basic Res Cardiol, 2021
Hegyi B, Pölönen RP, Hellgren KT, Ko CY, Ginsburg KS, Bossuyt J, Mercola M, Bers DM.   +7 more
europepmc   +1 more source

Polarized Light Microscopy for Quantitative Assessment of Sarcomere‐Scale Structural Order in Cardiac Tissue

Journal of Biophotonics, Volume 19, Issue 8, August 2026.
Impact of cardiac and respiratory arrest on cardiac muscle tissue. Wistar rats were injected (on the left) either with cisatracurium to induce a respiratory arrest or lidocaine to induce a cardiac arrest (in the middle). Further, the pathophysiological changes developed and were assessed with linear polarization microscopy at 600–3000 nm wavelength ...
Gennadii Piavchenko, Artem Venediktov, Zoya Shamitko, Karina Urazova, Mariia Obelchakova, Evelina Khabarova, Anton Ershov, Natalia Kartashkina, Viktoria Grikh, Valerii Smirnov, Galina Ramenskaya, Alexander Yatskovskiy, Igor Meglinski   +12 more
wiley   +1 more source

Divergent AKT Signalling Mechanisms Regulate GLUT4 Translocation and Glucose Uptake in Skeletal Muscle and Adipose Tissue

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 4, August 2026.
ABSTRACT Background The serine/threonine kinase AKT is a key regulator of glucose and energy metabolism. Prevailing dogma suggests that AKT is an obligate intermediate for glucose uptake in all metabolic tissues and that impaired AKT signalling is a major molecular driver of insulin resistance in obesity.
Natasha Jaiswal, Matthew Gavin, Louise Lantier, Olivia Yu Yu Ong, David H. Wasserman, Paul M. Titchenell   +5 more
wiley   +1 more source

Detection of Ca2+ transients near ryanodine receptors by targeting fluorescent Ca2+ sensors to the triad. [PDF]

J Gen Physiol, 2021
Sanchez C, Berthier C, Tourneur Y, Monteiro L, Allard B, Csernoch L, Jacquemond V.   +6 more
europepmc   +1 more source