Results 91 to 100 of about 3,085,356 (235)

L'enseignement du portugais brésilien à Genève: une séquence didactique adaptée au contexte LCO

open access: yesBabylonia, 2023
Cette contribution a pour but de discuter de la mise en œuvre d’un dispositif didactique visant l’enseignement et l’apprentissage de la lecture et de la production orale collective d’une histoire dans une classe de portugais brésilien langue d’origine ...
Carla Silva-Hardmeyer   +2 more
doaj  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Approche sémiologique d'une séquence d'Ulysse 31

open access: yes, 1983
Sublet Françoise. Approche sémiologique d'une séquence d'Ulysse 31. In: Pratiques : linguistique, littérature, didactique, n°37, 1983. La télé à l'école. pp.
Sublet, Françoise
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

[S1] Bilan de la séquence

open access: yes, 2013
Nous voici rendu au terme de la première séquence du cours, voici donc quelques éléments de bilan que vous pouvez compléter en commentaire si vous le souhaitez.
Jean-Michel Salaun
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Concevoir une séquence d’enseignement-apprentissage de l’adjectif : pièges et difficultés en formation initiale

open access: yesLidil
Our contribution analyses the traces of students undergoing initial teacher training for primary teaching. In writings on the preparation of sequences on the adjective and extracts from their research dissertations, we observe how novice teachers deal ...
Annette Schmehl-Postaï
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Séquence 0 : Séquence introductive - Présentation des outils et définitions

open access: yes
MasterAn ontology covering food engineering, animal feed, bioproducts, and biowaste, with a view to integrating data into a circular bioeconomy using a nexus-oriented approach, has been proposed in order to resolve data harmonization issues.
Dervaux, Stéphane   +4 more
core  

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