Results 81 to 90 of about 3,222,582 (225)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Séquence 1. « En France qui gouverne le mouvement sportif ? »
Alain BRAUN,Administrateur de l’UNCU et animateur de la séquence Bonjour à toutes et à tous, bienvenue à la première séquence de notre 30e Université Sportive d’Été.
Braun, Alain
core +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Sortir du plan-séquence collapsologue ?
International audienceLes réalisateurs de la série L’effondrement, diffusée l’an dernier sur Canal + ont fait le choix filmique du plan-séquence pour nous immerger dans la réalité (provisoirement fictionnelle) d’un écroulement de nos institutions et de ...
Citton, Yves, Rasmi, Jacopo
core
LA SÉQUENCE D'ENTIERS A348960.: a(n) = ⌊log(πn!)⌋
This is a sequence of integers that was registered in the On-line Encyclopedia of Integers (OEIS) under the code: A348960. In this report, the sequence is evaluated for integers n taking values within the range [0,70]. An algorithm in MATHEMATICA for the
Marrero Romero, Paul Francisco
core +2 more sources
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
L'enseignement du portugais brésilien à Genève: une séquence didactique adaptée au contexte LCO
Cette contribution a pour but de discuter de la mise en œuvre d’un dispositif didactique visant l’enseignement et l’apprentissage de la lecture et de la production orale collective d’une histoire dans une classe de portugais brésilien langue d’origine ...
Carla Silva-Hardmeyer +2 more
doaj
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source

