Results 81 to 90 of about 3,085,356 (235)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Cahiers d'enfance, séquence du Crayon de bouche
, 1995 Cahiers d'enfance, séquence du Crayon de bouche. In: Genesis (Manuscrits-Recherche-Invention), numéro 8, 1995. Psychanalyse. pp.
core +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
LA SÉQUENCE D'ENTIERS A348960.: a(n) = ⌊log(πn!)⌋
, 2021 This is a sequence of integers that was registered in the On-line Encyclopedia of Integers (OEIS) under the code: A348960. In this report, the sequence is evaluated for integers n taking values within the range [0,70]. An algorithm in MATHEMATICA for the
Marrero Romero, Paul Francisco
core +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
L’intubation en séquence rapide
, 2015 Résumé Objectif : Revoir les huit étapes de l’intubation en séquence rapide. Connaître les principales caractéristiques pharmacologiques des médicaments utilisés au cours d’une intubation en séquence rapide ainsi que les situations cliniques dans ...
Têtu, Rébecca
core
Les Rongeurs et la séquence climatique tardiglaciaire
, 1994 Chaline Jean. Les Rongeurs et la séquence climatique tardiglaciaire. In: Gallia préhistoire, tome 36, 1994. pp.
Chaline, Jean, Jean Chaline
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FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
"Satisfaction garantie" - séquence 3a : L’arrivée de l'humanoïde
, 2014 Résumé de la séquence : L’instant choisi dans la nouvelle d’Isaac Asimov correspond à l’arrivée du robot, Tony, chez Monsieur et Madame Belmont. Le Docteur Calvin explique alors le but de l’expérience, décrivant notamment toutes les caractéristiques de ...
vincentduquennoy
core +1 more source
Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila
FEBS Letters, EarlyView.Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia +6 more
wiley +1 more source