Results 61 to 70 of about 15,708 (115)

De‐nitrosylation Coordinates Appressorium Function for Infection of the Rice Blast Fungus

open access: yesAdvanced Science
As a signaling molecule, nitric oxide (NO) regulates the development and stress response in different organisms. The major biological activity of NO is protein S‐nitrosylation, whose function in fungi remains largely unclear.
Hong Hu   +9 more
doaj   +1 more source

Towards an integrated molecular understanding of plant hormones

open access: yesJournal of Integrative Plant Biology, Volume 68, Issue 8, Page 2787-2826, August 2026.
This review offers a comprehensive overview of the nine plant hormones, delving into their biosynthesis, transport, signaling and crosstalk mechanisms. Because the complexity of plant hormonal control goes beyond these core elements, additional specific features are discussed. Lastly, this review highlights how fundamental insights drive hormonal‐based
Louise Vilain   +2 more
wiley   +1 more source

Activation of hepatic acetyl-CoA carboxylase by S-nitrosylation in response to diet

open access: yesJournal of Lipid Research
Nitric oxide (NO), produced primarily by nitric oxide synthase enzymes, is known to influence energy metabolism by stimulating fat uptake and oxidation. The effects of NO on de novo lipogenesis (DNL), however, are less clear.
Nicholas M. Venetos   +4 more
doaj   +1 more source

Decoding MAPK cascades in plant immunity: Activation, regulation, integration, and pathogen manipulation

open access: yesJournal of Integrative Plant Biology, Volume 68, Issue 8, Page 3000-3024, August 2026.
This review focuses on mitogen‐activated protein kinase (MAPK) activation and summarizes how plants regulate and integrate MAPK signaling in modulating plant immune responses. It also examines the effectors pathogens have evolved to manipulate MAPK activation and thereby inhibit plant immunity.
Guitao Zhong   +3 more
wiley   +1 more source

Nitric Oxide Tunes Secreted Metabolite Bioactivity

open access: yesMolecular Microbiology, Volume 126, Issue 2, Page 145-160, August 2026.
Pseudomonas aeruginosa produces phenazine metabolites that can react with nitric oxide (·NO) to form nitrosylated compounds. The formation of these metabolites results in rapid loss in P. aeruginosa viability and diminishes phenazine antimicrobial activity against other organisms, including Staphylococcus aureus. ABSTRACT The radical nitric oxide (·NO)
Zachery R. Lonergan   +7 more
wiley   +1 more source

Regulation by S-nitrosylation of the Calvin-Benson cycle fructose-1,6-bisphosphatase in Pisum sativum

open access: yesRedox Biology, 2018
Redox regulation is of great importance in chloroplasts. Many chloroplast enzymes, such as those belonging to the Calvin-Benson cycle (CBC), have conserved regulatory cysteines which form inhibitory disulphide bridges when physiological conditions become
Antonio Jesús Serrato   +3 more
doaj   +1 more source

Pd(II)‐Catalyzed Strategies for the β‐Arylation of α‐Amino Acids: An Overview

open access: yesChemistry – A European Journal, Volume 32, Issue 28, 25 July 2026.
The graphical abstract summarizes the review “Pd(II)‐Catalyzed Strategies for the β‐Arylation of α‐Amino Acids: An Overview”, highlighting representative Pd(II)‐catalyzed methods for the β‐arylation of α‐amino acids. Key mechanistic features, substrate diversity, and synthetic relevance of these transformations are showcased. Abstract Metal‐catalyzed C─
Davide Illuminati   +4 more
wiley   +1 more source

Computational Structural Biology of S-nitrosylation of Cancer Targets

open access: yesFrontiers in Oncology, 2018
Nitric oxide (NO) plays an essential role in redox signaling in normal and pathological cellular conditions. In particular, it is well known to react in vivo with cysteines by the so-called S-nitrosylation reaction.
Emmanuelle Bignon   +5 more
doaj   +1 more source

PDI Knockdown Inhibits Seizure Activity in Acute Seizure and Chronic Epilepsy Rat Models via S-Nitrosylation-Independent Thiolation on NMDA Receptor

open access: yesFrontiers in Cellular Neuroscience, 2018
Redox modulation and S-nitrosylation of cysteine residues are the post-translational modifications of N-methyl-D-aspartate receptor (NMDAR) to regulate its functionality. Recently, we have reported that protein disulfide isomerase (PDI) reduces disulfide
A. Ran Jeon, Ji-Eun Kim
doaj   +1 more source

Protein stereo‐folding and proteostasis: A new path for clinical and translational medicine

open access: yes
Clinical and Translational Discovery, Volume 6, Issue 4, August 2026.
Yuhan Wang, Yuyang Qiu, Xiangdong Wang
wiley   +1 more source

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