Results 141 to 150 of about 37,335 (238)
Neurons require efficient trafficking and delivery of neuronal proteins and organelles to specific subcellular locations. Dynein and kinesin motors mediate long-distance transport of cargo along microtubules spanning the axon to maintain neuronal function.
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ChemMedChem, Volume 21, Issue 15, 14 August 2026.Temporins, among antimicrobial peptides, are short frog‐derived molecules with potent antibacterial activity. This review highlights chemical optimization strategies applied to temporins A–L, showing how sequence tuning modulates structure, stability, and selectivity, enabling improved activity against resistant pathogens.
Ida Boccino +2 more
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New Biobased Polyester Polyols With Tunable Tg Values From 4‐Vinylguaiacol‐Derived Monomers
ChemSusChem, Volume 19, Issue 15, 14 August 2026.Biobased low‐molecular‐weight polyesters were obtained by ROCOP of guaiacol‐derived epoxides with cyclic anhydrides. Varying the length of the acyl moieties on the epoxides and the cyclic anhydride structures, it is possible to tune the Tg's within an 80 ºC wide temperature range.
Erika Zangelmi +4 more
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A Piezo‐Mimetic Ionic Hydrogel Harnessing Joint Motion for Cartilage Repair
Advanced Science, Volume 13, Issue 43, 3 August 2026.A piezo‐mimetic ionic hydrogel converts mechanical deformation into bioactive ionic currents via stress‐induced asymmetric ion migration. Coupled with sustained Mg2+ release, this mechano‐electrochemical platform bridges mechanical loading and cellular signaling, enabling load‐adaptive stimulation and enhanced cartilage regeneration. ABSTRACT Articular
Chenyuan Gao +14 more
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FoxO1-zDHHC4-CD36 S-Acylation Axis Drives Metabolic Dysfunction in Diabetes. [PDF]
Circ ResDennis KMJH +25 more
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An atlas of Arabidopsis protein S-acylation reveals its widespread role in plant cell organization and function. [PDF]
Nat Plants, 2022 Kumar M, Carr P, Turner SR.
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Role of S-acylating enzymes in ciliated cells
S-acylation is a post-translational modification that can regulate protein localization, function, and turnover by reversible attachment of fatty acid to specific cysteine residues. It affects over 20% of proteins, with membrane proteins making up the largest group, followed by cytosolic, ciliary, and nuclear proteins.
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Stage‐Specific H3K14 and H3K23 Succinylation Orchestrates Insect Metamorphosis and Oogenesis
Advanced Science, Volume 13, Issue 43, 3 August 2026.Stage‐specific succinylation of histone H3 at lysine 14 and 23 differentially controls insect metamorphosis and oogenesis through distinct GPCR‐PKC signaling cascades, revealing an evolutionarily conserved epigenetic mechanism that coordinates key life‐history traits.
Yu‐Pu Jing +9 more
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Dynamic PRDX S-acylation modulates ROS stress and signaling. [PDF]
Cell Chem BiolQiu T, Azizi SA, Pani S, Dickinson BC.
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Insights Into the Biological Mechanisms and Multifunctional Health Benefits of Morelloflavone
eFood, Volume 7, Issue 4, August 2026.Morelloflavone (MF), a biflavonoid from Garcinia and related species, exhibits broad human health benefits through antioxidant, anti‐inflammatory, anticancer, and metabolic regulatory effects. This review highlights its molecular mechanisms, biosynthesis, and emerging roles in chronic disease prevention, emphasizing systems biology and machine learning
Yi Liu +4 more
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