The endoplasmic reticulum-localized enzyme zDHHC6 mediates S-acylation of short transmembrane constructs from multiple type I and II membrane proteins. [PDF]
Salaun C, Tomkinson NCO, Chamberlain LH.
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Conservation of post‐translational modifications (PTMs) in histones across six plant species.
Sau‐Shan Cheng +3 more
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In vitro reconstitution in membrane environment reveals critical lipid dependence of substrate S-acylation by protein palmitoyltransferase enzymes. [PDF]
Mondal T, Banerjee A.
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S-acylation of Sprouty and SPRED proteins by the S-acyltransferase zDHHC17 involves a novel mode of enzyme-substrate interaction. [PDF]
Butler L +7 more
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High‐Resolution LC–MS/MS Characterization of Budmunchiamine‐Type Alkaloids in Albizia niopoides
ABSTRACT Rationale Budmunchiamines are macrocyclic spermine alkaloids that constitute a distinctive class of polyamine natural products predominantly found in species of the genus Albizia. Comprehensive characterization of these compounds remains challenging because of their structural diversity and the limited availability of reference standards. This
Maria L. A. Majevski +6 more
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The role of protein S-acylation in vascular injury associated with metabolic disorders. [PDF]
Wang Y +8 more
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We have developed a visible‐light‐driven, transition‐metal‐free protocol for the chemodivergent borocarbonylation of trifluoromethyl styrenes which integrates radical 1,2‐boron migration, CO trapping, and intermolecular C–C bond formation into a single multicomponent cascade.
Xiao‐Fan Cui +2 more
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Correction: The role of protein S-acylation in vascular injury associated with metabolic disorders. [PDF]
Wang Y +8 more
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Development of a novel high-throughput screen for the identification of new inhibitors of protein S-acylation. [PDF]
Salaun C +8 more
europepmc +1 more source
Oxysterols in Cancer: From Biosynthesis and Pathophysiology to Targeted Therapeutics
Mechanisms by which oxysterol targeting may enhance immunotherapy efficacy. This figure illustrates potential metabolic interventions that may improve antitumor immunity by modulating oxysterol related pathways. CH25H modulation may reduce 25‐HC accumulation, promote the conversion of cold tumors into hot tumors, and increase T cell infiltration and PD‐
Haili Shang, Yongsheng Li
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