Results 181 to 190 of about 37,527 (267)

Site‐Selective Ligand Selection by Mutational Profiling for Covalent RNA Targeting

Angewandte Chemie, Volume 138, Issue 6, 2 February 2026.
Using a mutational profiling approach an RNA‐targeted covalent probe was developed that is highly selective for the FMN riboswitch. The covalency was further supported by mass spectrometry experiments. The covalent probe selectively modifies the riboswitch at low micromolar concentrations within 10 min and remains functional when applied to an entire ...
Phillip Yesley, Georgia Poulladofonou, Danny Incarnato, Willem A. Velema   +3 more
wiley   +2 more sources

S-acylation of Sprouty and SPRED proteins by the S-acyltransferase zDHHC17 involves a novel mode of enzyme-substrate interaction. [PDF]

J Biol Chem, 2023
Butler L, Locatelli C, Allagioti D, Lousa I, Lemonidis K, Tomkinson NCO, Salaun C, Chamberlain LH.   +7 more
europepmc   +1 more source

Genome and Single‐Cell Transcriptome Reveal the Evolution of Holoparasitic Plants: A Case Study of Cistanche deserticola

Plant Biotechnology Journal, EarlyView.
ABSTRACT The Orobanchaceae family, the largest group of parasitic plants, spans a complete spectrum from autotrophic to holoparasitic species. As a typical endangered holoparasitic species within this family, Cistanche deserticola is a parasitic plant that is widely harvested for traditional medicine in desertic regions, and of growing importance as a ...
Xinke Zhang, Yujing Miao, Yuanyuan Xing, Guoshuai Zhang, Meiqiao Zhang, Chris J. Thorogood, Shilin Chen, Linfang Huang   +7 more
wiley   +1 more source

Stereospecific Transition‐Metal‐Free Alkylation of Chiral Non‐Racemic Secondary Tosylates with Cyanohydrins: Convenient Access to Enantiomerically Enriched α‐Tertiary Ketones

Angewandte Chemie, Volume 138, Issue 6, 2 February 2026.
A stereospecific, transition‐metal‐free SN2 alkylation of cyanohydrins with chiral non‐racemic secondary tosylates is reported, providing efficient access to enantioenriched α‐tertiary ketones. The method exhibits broad substrate scope, operational simplicity, and excellent stereospecificity, including stereoconvergent reactions of E/Z mixtures of ...
Jinjin Ma, Hui Li, Jadab Majhi, P. Andrew Evans   +3 more
wiley   +2 more sources

New protein fluorescent labeling methods for carbonylation and S-acylation studies in plants [PDF]

BIO Web of Conferences
Román Andrea, Priego Salvador, Castro Antonio J., Alche Juan De Dios   +3 more
doaj   +1 more source

Expression of a Bacterial Trehalose 6‐Phosphate Synthase Gene otsA in Camelina sativa Seeds Promotes the Channelling of Carbon Towards Oil Accumulation

Plant Biotechnology Journal, EarlyView.
ABSTRACT Improving seed oil yield is essential for developing Camelina sativa as a sustainable biofuel crop. Fatty acid synthesis depends on the production of acetyl‐CoA from photosynthetically derived sugars. Trehalose 6‐phosphate (T6P), a proxy for sucrose availability, can link sugar status to plant growth and development. Synthesised by trehalose 6‐
Saroj Kumar Sah, Zhiyang Zhai, Hai Shi, Jin Chai, Elen Deng, Jorg Schwender, Xiao‐Hong Yu, John Shanklin   +7 more
wiley   +1 more source

Nanoparticle‐Based Tolerogenic Vaccines: Next‐Generation Strategies for Autoimmune and Allergic Disease Therapies

Angewandte Chemie, Volume 138, Issue 6, 2 February 2026.
Nanoparticle‐based tolerogenic vaccines harness controlled antigen delivery and immunomodulation to establish tolerance in autoimmunity and allergy. This review outlines how nanoparticle design (size, shape, composition, administration route) influences biodistribution and immune‐cell targeting.
Benjamin E. Nachod, Ajay S. Thatte, Rohan Palanki, Michael J. Mitchell   +3 more
wiley   +2 more sources

The role of protein S-acylation in vascular injury associated with metabolic disorders. [PDF]

Front Endocrinol (Lausanne)
Wang Y, Zhu W, Wang W, Zhang J, Hu D, Shao H, Zhou Y, Wang S, Zhao L.   +8 more
europepmc   +1 more source

Faculty Opinions recommendation of Rif1 S-acylation mediates DNA double-strand break repair at the inner nuclear membrane.

, 2019
Catherine A. Fox
openalex   +2 more sources

Influence of Additional Acylation Site(s) of Influenza B Virus Hemagglutinin on Syncytium Formation [PDF]

, 2005
Makoto Ujike, Katsuhisa Nakajima, Eri Nobusawa   +2 more
openalex   +1 more source