Results 71 to 80 of about 21,334,376 (275)
Oxidative acylation of sulfoximines with methylarenes as an acyl donor [PDF]
RSC Advances, 2015 An efficient direct oxidative acylation of sulfoximines with methylarenes as an acyl donor was finally achieved.
Junfeng Zhao +4 more
openaire +2 more sources
Polyglutamine Tract Expansion Increases S-Nitrosylation of Huntingtin and Ataxin-1. [PDF]
PLoS ONE, 2016 Expansion of the polyglutamine (polyQ) tract in the huntingtin (Htt) protein causes Huntington's disease (HD), a fatal inherited movement disorder linked to neurodegeneration in the striatum and cortex.
Chun-Lun Ni +8 more
doaj +1 more source
Stearic acid blunts growth-factor signaling via oleoylation of GNAI proteins
Nature Communications, 2021 S-acylation is the post-translational covalent attachment of fatty acids (FA) onto cysteines. Nuskova et al. find that exposure of cells to different FAs affects which FA is used to S-acylate GNAI proteins, thereby altering GNAI function and EGFR pathway
Hana Nůsková +8 more
doaj +1 more source
Molecules, 2022 Amides, anhydrides, esters, and thioesters of 2H-azirine-2-carboxylic acids were prepared by a rapid procedure at room temperature involving FeCl2-catalyzed isomerization of 5-chloroisoxazoles to 2H-azirine-2-carbonyl chlorides, followed by reaction with
Anastasiya V. Agafonova +2 more
doaj +1 more source
S‐Acyl and N‐Acyl Derivatives of Benzothiazole‐2‐thiol: An Example of Acyl Group Rearrangement. [PDF]
ChemInform, 2007 AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Joung Hee Lee +2 more
openaire +3 more sources
Interplay between RNA‐protein interactions and RNA structures in gene regulation
FEBS Open Bio, EarlyView.Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko +2 more
wiley +1 more source
Advanced Functional Materials, EarlyView.By turning off hydrogen bonds by bulky ethyl cinnamate ester derivatization, softwood kraft lignin can flow under elevated temperatures, providing tough fiber in the melt for high take‐up speed. Subsequently, lignin ethyl cinnamate derivatives are readily stabilized with only dilute nitric acid leading to direct carbonized fiber with outstanding ...
Qi Hua +8 more
wiley +1 more source
Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs
Advanced Healthcare Materials, EarlyView.Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner +8 more
wiley +1 more source
Acylation – A New Means to Control Traffic Through the Golgi
Frontiers in Cell and Developmental Biology, 2019 The Golgi is well known to act as center for modification and sorting of proteins for secretion and delivery to other organelles. A key sorting step occurs at the trans-Golgi network and is mediated by protein adapters. However, recent data indicate that
Andreas M. Ernst +3 more
doaj +1 more source
Supramolecular Chemistry in Metal–Organic Framework Materials
Advanced Materials, EarlyView.This review highlights synergies between reticular chemistry and supramolecular chemistry. The role of supramolecular interactions in determining framework…guest interactions and attempts to understand dynamic behavior in metal–organic frameworks (MOFs), particularly emphasizing the development of crystal sponges, studying reactions in frameworks and ...
Eugenia Miguel‐Casañ +3 more
wiley +1 more source