Results 131 to 140 of about 4,880 (161)

Kinetics of S-Nitrosation of Thiols in Nitric Oxide Solutions

Chemical Research in Toxicology, 1996
The S-nitroso adducts of nitric oxide (NO) may serve as carriers of NO and play a role in cell signaling and/or cytotoxicity. A quantitative understanding of the kinetics of S-nitrosothiol formation in solutions containing NO and O2 is important for understanding these roles of S-nitroso compounds in vivo.
M, Keshive, S, Singh, J S, Wishnok, S R, Tannenbaum, W M, Deen   +4 more
openaire   +2 more sources

Reversible S-Nitrosation and Inhibition of HIV-1 Protease

Biochemistry, 1999
Nitric oxide (*NO) is a short-lived free radical with many functions including vasoregulation, synaptic plasticity, and immune modulation and has recently been associated with AIDS pathology. Various pathophysiological conditions, such as viral infection, trigger inducible nitric oxide synthase (iNOS) to synthesize NO in the cell.
P K, Sehajpal, A, Basu, J S, Ogiste, H M, Lander   +3 more
openaire   +2 more sources

S-nitrosation of glutathione by nitric oxide, peroxynitrite, and •NO/O2•−

Free Radical Biology and Medicine, 2003
To elucidate potential mechanisms of S-nitrosothiol formation in vivo, we studied nitrosation of GSH and albumin by nitric oxide ((*)NO), peroxynitrite, and (*)NO/O(2)(*)(-). In the presence of O(2), (*)NO yielded 20% of S-nitrosoglutathione (GSNO) at pH 7.5.
Astrid, Schrammel, Antonius C F, Gorren, Kurt, Schmidt, Silvia, Pfeiffer, Bernd, Mayer   +4 more
openaire   +2 more sources

Nitric oxide production and protein S-nitrosation in algae

Plant Science
Key roles for nitric oxide in signalling processes and plant physiological processes are now well established. In particular, the identification and functional characterisation of proteins regulated by S-nitrosation, a NO-dependent post-translational modification, provided remarkable insights into the subtle mechanisms by which NO mediates its effects.
Chaudron, Zoé, Nicolas-Francès, Valérie, Pichereaux, Carole, Hichami, Siham, Rosnoblet, Claire, Besson-Bard, Angelique, Wendehenne, David   +6 more
openaire   +2 more sources

S-nitrosation of cysteine as evidenced by IRMPD spectroscopy

International Journal of Mass Spectrometry, 2012
Abstract S-nitrosation of cysteine plays an important role in storage and transport of NO, a key signaling molecule in vivo . An approach to detect this modification in the bare, charged amino acid is presented, based on IR multiple photon dissociation (IRMPD) spectroscopy.
LANUCARA, FRANCESCO, CHIAVARINO, Barbara, CRESTONI, Maria Elisa, Debora Scuderi, Rajeev K. Sinha, Philippe Maitre, FORNARINI, Simonetta   +6 more
openaire   +2 more sources

Sensing Hypoxia by Mitochondria: A Unifying Hypothesis Involving S-Nitrosation

Antioxidants & Redox Signaling, 2014
Significance: Sudden hypoxia requires a rapid response in tissues with high energy demand. Mitochondria are rapid sensors for a lack of oxygen, but no consistent mechanism for the sensing process and the subsequent counter-regulation has been described.
Volker, Ullrich, Stefan, Schildknecht
openaire   +2 more sources

Detection and Proteomic Identification of S‐Nitrosated Proteins in Human Hepatocytes

2008
The S-nitrosation of protein thiols is a redox-based posttranslational modification that modulates protein function and cell phenotype. Although the detection of S-nitrosated proteins is problematical because of the lability of S-nitrosothiols, an increasing range of proteins has been shown to undergo S-nitrosation with the improvement of molecular ...
Rodriguez-Ariza, A. (Antonio), Corrales, F.J. (Fernando José), Muntane, J. (Jordi), Lopez-Sanchez, L.M. (Laura M.), Mata, M. (Manuel) de la   +4 more
openaire   +3 more sources

Reaction of a nitrosamine with thiourea- A direct S-nitrosation

Journal of the Chemical Society, Chemical Communications, 1975
Thiourea reacts with N-methyl-N-nitrosoaniline without the intermediacy of a free nitrosating agent, to form an S-nitroso-compound; thiourea shows comparable nucleophilic reactivity to iodide ion in this reaction.
openaire   +1 more source

Redox‐Neutral S ‐nitrosation Mediated by a Dicopper Center

Angewandte Chemie - International Edition, 2021
Shiyu Zhang, Curtis E Moore Curtis Moore, Wenjie Tao   +2 more
exaly  

S-Nitrosation

2021
openaire   +1 more source