Results 81 to 90 of about 15,774 (176)
Nitric Oxide Tunes Secreted Metabolite Bioactivity
Molecular Microbiology, Volume 126, Issue 2, Page 145-160, August 2026.Pseudomonas aeruginosa produces phenazine metabolites that can react with nitric oxide (·NO) to form nitrosylated compounds. The formation of these metabolites results in rapid loss in P. aeruginosa viability and diminishes phenazine antimicrobial activity against other organisms, including Staphylococcus aureus. ABSTRACT The radical nitric oxide (·NO)
Zachery R. Lonergan +7 more
wiley +1 more source
Redox Biology, 2018 Redox regulation is of great importance in chloroplasts. Many chloroplast enzymes, such as those belonging to the Calvin-Benson cycle (CBC), have conserved regulatory cysteines which form inhibitory disulphide bridges when physiological conditions become
Antonio Jesús Serrato +3 more
doaj +1 more source
Pd(II)‐Catalyzed Strategies for the β‐Arylation of α‐Amino Acids: An Overview
Chemistry – A European Journal, Volume 32, Issue 28, 25 July 2026.The graphical abstract summarizes the review “Pd(II)‐Catalyzed Strategies for the β‐Arylation of α‐Amino Acids: An Overview”, highlighting representative Pd(II)‐catalyzed methods for the β‐arylation of α‐amino acids. Key mechanistic features, substrate diversity, and synthetic relevance of these transformations are showcased. Abstract Metal‐catalyzed C─
Davide Illuminati +4 more
wiley +1 more source
Computational Structural Biology of S-nitrosylation of Cancer Targets
Frontiers in Oncology, 2018 Nitric oxide (NO) plays an essential role in redox signaling in normal and pathological cellular conditions. In particular, it is well known to react in vivo with cysteines by the so-called S-nitrosylation reaction.
Emmanuelle Bignon +5 more
doaj +1 more source
Frontiers in Cellular Neuroscience, 2018 Redox modulation and S-nitrosylation of cysteine residues are the post-translational modifications of N-methyl-D-aspartate receptor (NMDAR) to regulate its functionality. Recently, we have reported that protein disulfide isomerase (PDI) reduces disulfide
A. Ran Jeon, Ji-Eun Kim
doaj +1 more source
Protein stereo‐folding and proteostasis: A new path for clinical and translational medicine
Clinical and Translational Discovery, Volume 6, Issue 4, August 2026.
Yuhan Wang, Yuyang Qiu, Xiangdong Wang
wiley +1 more source
Nitric Oxide Regulates Multiple Signal Pathways in Plants via Protein S-Nitrosylation
Current Issues in Molecular BiologyNitric oxide (NO) can perform its physiological role through protein S-nitrosylation, a redox-based post-translational modification (PTM). This review details the specific molecular mechanisms and current detection technologies of S-nitrosylation.
Wei Lin +4 more
doaj +1 more source
Communications BiologyAlzheimer’s disease (AD), characterized by cognitive decline, is increasingly recognized as a disorder marked by synaptic loss and dysfunction. Despite this understanding, the underlying pathophysiological mechanisms contributing to synaptic impairment ...
Aobing Cheng +6 more
doaj +1 more source
Differential S-nitrosylation of proteins in Alzheimer’s disease
Neuroscience, 2014 Numerous studies have provided evidence regarding the involvement of protein S-nitrosylation in the progression of Alzheimer's disease (AD) pathology and its implication in the formation and accumulation of misfolded protein aggregates. The identification of S-nitrosylated proteins can be a major step toward the understanding of mechanisms leading to ...
Zahid, Saadia +4 more
openaire +3 more sources
Experimental and Molecular MedicineGenotoxic therapy triggers reactive oxygen species (ROS) production and oxidative tissue injury. S-nitrosylation is a selective and reversible posttranslational modification of protein thiols by nitric oxide (NO), and 5,6,7,8-tetrahydrobiopterin (BH4) is
Yang Feng +15 more
doaj +1 more source