Results 121 to 130 of about 3,196,686 (255)

S-phase PARylation of microprotein RSMC enhances the function of Sororin in sister chromatid cohesion. [PDF]

open access: yesEMBO J
Jiang M   +15 more
europepmc   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Influence of Post-Processing on S-Phase Formation During Plasma Nitriding of Additively Manufactured Inconel 939. [PDF]

open access: yesMaterials (Basel)
Maj P   +7 more
europepmc   +1 more source

Asymmetric distribution of parental H3K9me3 in S phase silences L1 elements. [PDF]

open access: yesNature, 2023
Li Z   +10 more
europepmc   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Precise control of transcription condensates across S phase balances linker histone expression with DNA replication, ensuring genome stability. [PDF]

open access: yesMol Cell
Marmolejo CO   +8 more
europepmc   +1 more source

Switching on S phase [PDF]

open access: yesNature Reviews Molecular Cell Biology, 2001
openaire   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

scRepli-RamDA-seq: a multi-omics technology enabling the analysis of gene expression dynamics during S-phase. [PDF]

open access: yesNat Commun
Poonperm R   +13 more
europepmc   +1 more source

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