Results 131 to 140 of about 21,351,086 (309)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

DFT Insights into MAX Phase Borides Hf2AB [A = S, Se, Te] in Comparison with MAX Phase Carbides Hf2AC [A = S, Se, Te]

open access: yesACS Omega, 2023
Jakiul Islam   +8 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Two-phase flow experimental studies in micro-models

open access: yes, 2013
The aim of this research project was to put more physics into theories of two-phase flow. The significance of including interfacial area as a separate variable in two-phase flow and transport models was investigated.
Physically-based theory of two-phase flow in porous media including fluid-fluid interfacial area   +2 more
core  

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Black-holes, topological strings and large N phase transitions

open access: yes, 2005
The counting of microstates of BPS black-holes on local Calabi-Yau of the form (p-2)?(-p) S2 is explored by computing the partition function of q-deformed Yang-Mills theory on S2. We obtain, at finite N, the instanton expansion of the gauge theory.
CIRAFICI M   +25 more
core   +1 more source

Innovation Cycles through the Impact on Market Capitalization of Companies and the Dominant Portfolio Construction Model

open access: yesEkonomski Vjesnik, 2010
Innovation cycles have a direct influence on the level of economic activity and the phase of economic cycle. Furthermore, they influence the development of new branches of economy, industries, technologies, business models and products.
Emil Mihalina
doaj  

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