Results 21 to 30 of about 3,196,686 (255)

Step-wise assembly, maturation and dynamic behavior of the human CENP-P/O/R/Q/U kinetochore sub-complex [PDF]

, 2012
Kinetochores are multi-protein megadalton assemblies that are required for attachment of microtubules to centromeres and, in turn, the segregation of chromosomes in mitosis. Kinetochore assembly is a cell cycle regulated multi-step process.
Bancroft, James M., Cardoso, M. Cristina, Deng, Wen, Diekmann, Stephan, Döring, Volker, Emmerth, Stephan, Eskat, Anja, Hellwig, Daniela, Hofmeister, Antje, Hoischen, Christian, Leonhardt, Heinrich, McAinsh, Andrew D., Meraldi, Patrick, Rudolphi, Sven, Ulbricht, Tobias   +14 more
core   +8 more sources

The Arabidopsis thaliana checkpoint kinase WEE1 protects against premature vascular differentiation during replication stress [PDF]

, 2011
A sessile lifestyle forces plants to respond promptly to factors that affect their genomic integrity. Therefore, plants have developed checkpoint mechanisms to arrest cell cycle progression upon the occurrence of DNA stress, allowing the DNA to be ...
Cools, Toon, Iantcheva, Anelia, Weimer, Annika K, Boens, Shannah, Takahashi, Naoki, Maes, Sara, Van Den Daele, Hilde, Van Isterdael, Gert, Schnittger, Arp, De Veylder, Lieven   +9 more
core   +2 more sources

Dicer prevents genome instability in response to replication stress [PDF]

, 2019
Dicer, an endoribonuclease best-known for its role in microRNA biogenesis and RNA interference pathway, has been shown to play a role in the DNA damage response and repair of double-stranded DNA breaks (DSBs) in mammalian cells.
Barra, Viviana, Bordignon, Benoit, Coquelle, Arnaud, Egger, Tom, Fragkos, Michalis, Lemacon, Delphine, Naim, Valeria   +6 more
core   +2 more sources

Statistical Study of the Corrosion Behavior of Al2CuMg Intermetallics in AA2024-T351 by SKPFM [PDF]

, 2008
A statistical study combining atomic force microscopy, scanning Kelvin probe force microscopy (SKPFM), and energy-dispersive spectroscopy was carried out on more than 300 Al2CuMg intermetallic particles of AA2024 alloy to determine their corrosion ...
Blanc, Christine, Lacroix, Loïc, Mankowski, Georges, Ressier, Laurence   +3 more
core   +3 more sources

Spontaneous Fluxon Production in Annular Josephson Tunnel Junctions in the Presence of a Magnetic Field [PDF]

, 2007
We report on the spontaneous production of fluxons in the presence of a symmetry-breaking magnetic field for annular Josephson tunnel junctions during a thermal quench. The dependence on field intensity $B$ of the probability $\bar{f_1}$ to trap a single
A. Barone, B. I. Halperin, J. M. Rowell, J. Mygind, M. Aaroe, R. J. Rivers, R. Monaco, V. P. Koshelets, W. H. Zurek   +8 more
core   +3 more sources

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Why and When Are Evidence‐Based Interventions Adopted in Paediatric Supportive Care? A Qualitative Exploration of the Determinants of Photobiomodulation Implementation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Oral mucositis is a common and debilitating side effect of childhood cancer and stem cell transplant treatments. It affects the quality of life of children and young people (CYP) and places a strain on services. Photobiomodulation is recommended for oral mucositis prevention in international guidance but is poorly implemented in UK ...
Claudia Heggie, Kara A. Gray‐Burrows, Peter F. Day, Bob Phillips, Carl A. Thompson   +4 more
wiley   +1 more source

Orientational transitions in a nematic confined by competing surfaces [PDF]

, 2001
The effect of confinement on the orientational structure of a nematic liquid crystal model has been investigated by using a version of density-functional theory (DFT).
A. Poniewierski, A. Šarlah, A.K. Sen, C.W. Oseen, E. Martín del Río, F.C. Frank, F.N. Braun, G. Barbero, G. Skac̆ej, G.D. Wall, H. Yokoyama, I. Rodríguez-Ponce, I. Rodríguez-Ponce, I. Rodríguez-Ponce, J. M. Romero-Enrique, J. Nehring, J. Quintana, L. F. Rull, M. Faetti, M.M. Telo da Gama, P.I.C. Teixeira, P.I.C. Teixeira, R. van Roij, Y. Martínez   +23 more
core   +1 more source

Dexamethasone for Chemotherapy‐Induced Nausea and Vomiting Prevention in Pediatric Patients: International Consensus

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An international Delphi panel of experts developed consensus statements to delineate the circumstances where the risks of dexamethasone as an antiemetic do and do not outweigh its benefits. Procedure Experts in supportive care of pediatric patients were invited to participate.
Negar Shavandi, Paula D. Robinson, Shana Jacobs, L. Lee Dupuis, the International Pediatric Dexamethasone Panel, Sameer Bakhshi, Tiene Bauters, Eva Brack, Simone Cesaro, Claire Fosbrook, Jason Freedman, Tamara MacDonald, Eloise Neumann, Venkatraman Radhakrishnan, Rod Rassekh, Florian Slimano, Johnathan Soggee, Joel Thompson, Marianne van de Wetering, Milena Villarroel, Jasper Wong   +20 more
wiley   +1 more source

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source