Results 1 to 10 of about 3,196,686 (255)

S-phase cancer associated lncRNAs [PDF]

open access: yesCell Cycle, 2018
Comment on: Ali MM, et al. Nature Communications 2018; 9:883.
Santhilal Subhash   +2 more
openaire   +2 more sources

S‐Phase phosphorylation of lamin B2 [PDF]

open access: yesFEBS Letters, 1995
Lamin B2 modification in synchronously dividing populations of human diploid fibroblasts was determined by 2‐dimensional gel electrophoresis and [32P]orthophosphate labelling. In quiescent (G0) and G1 cultures of HDF, lamin B2 migrated as 2 spots on 2‐dimensional gels.
Kill, Ian R., Hutchison, Christopher J.
openaire   +2 more sources

Developing S-phase control [PDF]

open access: yesGenes & Development, 2012
The duration of S phase in early embryos is often short, and then increases as development proceeds because of the appearance of late-replicating regions of the genome. In the April 1, 2012, issue of Genes & Development, Farrell and colleagues (pp.
openaire   +2 more sources

S-phase against S-phase tribopairs for biomedical applications

open access: yesWear, 2013
Abstract S-phase, or expanded austenite, is a corrosion resistant diffused hardened layer which can be created in austenitic stainless steels and cobalt–chromium(Co-Cr) alloys. It is a precipitate-free metastable supersaturated solid solution of nitrogen or carbon or both.
Buhagiar, Joseph P.   +4 more
openaire   +2 more sources

Defective S Phase Chromatin Assembly Causes DNA Damage, Activation of the S Phase Checkpoint, and S Phase Arrest

open access: yesMolecular Cell, 2003
The S phase checkpoint protects the genome from spontaneous damage during DNA replication, although the cause of damage has been unknown. We used a dominant-negative mutant of a subunit of CAF-I, a complex that assembles newly synthesized DNA into nucleosomes, to inhibit S phase chromatin assembly and found that this induced S phase arrest.
Ye, Xiaofen   +5 more
openaire   +2 more sources

Cdk1: Unsung Hero of S Phase? [PDF]

open access: yesCell Cycle, 2004
Cdk2 has been viewed as a key cell cycle regulator that is essential for S phase progression. The recent discovery that Cdk2 is not required for cell proliferation in mice now shows that other factors must be able to replace Cdk2 in stimulating DNA replication.
Marcin, Pacek   +2 more
openaire   +2 more sources

Regulation in S Phase by E2F [PDF]

open access: yesCell Cycle, 2004
The DNA synthetic S phase of the unperturbed cell cycle is a closed system, as compared to regulation of G(1) by external growth factors. The E2F family provides internal control in S phase by transcribing genes required for deoxynucleotide triphosphate (dNTP) and DNA synthesis.
Arthur B, Pardee   +2 more
openaire   +2 more sources

ORC and the intra-S-phase checkpoint: a threshold regulates Rad53p activation in S phase [PDF]

open access: yesGenes & Development, 2002
The intra-S-phase checkpoint in yeast responds to stalled replication forks by activating the ATM-like kinase Mec1 and the CHK2-related kinase Rad53, which in turn inhibit spindle elongation and late origin firing and lead to a stabilization of DNA polymerases at arrested forks.
Kenji, Shimada   +2 more
openaire   +2 more sources

Setting the Stage for S Phase [PDF]

open access: yesMolecular Cell, 2007
In a recent issue of Molecular Cell, Tyagi et al. (2007) show that E2F1, a positive regulator of S phase entry, recruits cofactor HCF-1 and associated hSet1/MLL histone H3 lysine 4 methyltransferase complex, facilitating the activation of genes required for proliferation.
openaire   +2 more sources

SnapShot: S-Phase Entry and Exit

open access: yesCell, 2019
S-phase entry and exit are regulated by hundreds of protein complexes that assemble "just in time," orchestrated by a multitude of distinct events. To help understand their interplay, we have created a tailored visualization based on the Minardo layout, highlighting over 80 essential events.
Burgess, Andrew   +5 more
openaire   +3 more sources

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