Results 1 to 10 of about 3,189,678 (161)

Critical Function of γH2A in S-Phase. [PDF]

PLoS Genetics, 2015
Phosphorylation of histone H2AX by ATM and ATR establishes a chromatin recruitment platform for DNA damage response proteins. Phospho-H2AX (γH2AX) has been most intensively studied in the context of DNA double-strand breaks caused by exogenous clastogens,
Eva Mejia-Ramirez, Oliver Limbo, Petra Langerak, Paul Russell   +3 more
doaj   +4 more sources

DePARylation is critical for S phase progression and cell survival [PDF]

eLife
Poly(ADP-ribose)ylation or PARylation by PAR polymerase 1 (PARP1) and dePARylation by poly(ADP-ribose) glycohydrolase (PARG) are equally important for the dynamic regulation of DNA damage response.
Litong Nie, Chao Wang, Min Huang, Xiaoguang Liu, Xu Feng, Mengfan Tang, Siting Li, Qinglei Hang, Hongqi Teng, Xi Shen, Li Ma, Boyi Gan, Junjie Chen   +12 more
doaj   +2 more sources

Impact of residual clonal plasma cells in S-phase at the time of autologous stem cell transplantation on clinical outcomes [PDF]

Blood Cancer Journal
Autologous stem cell transplantation (ASCT) is a key therapeutic strategy for many patients diagnosed with multiple myeloma (MM), yet early relapses post-transplant remains a major clinical challenge.
Tamer Hellou, Daniel G. Packard, Suheil Albert Atallah-Yunes, Ahauve M. Orusa, Shinichiro Suzuki, Shaji K. Kumar, Angela Dispenzieri, Saurabh Zanwar, Dragan Jevremovic, Horatiu Olteanu, Pedro Horna, Gregory Otteson, Francis K. Buadi, David Dingli, Suzanne R. Hayman, Prashant Kapoor, Nelson Leung, Joselle Cook, Nadine Abdallah, Moritz Binder, Eli Muchtar, Rahma Warsame, Taxiarchis V. Kourelis, Ronald S. Go, Yi Lin, S. Vincent Rajkumar, Wilson I. Gonsalves, Morie A. Gertz   +27 more
doaj   +2 more sources

HIGH PRECISION FULLY INTEGRATED AIRBORNE DIGITAL MAPPING SYSTEMS – STATE OF THE ART AND PERFORMANCE ANALYSIS [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2020
This paper introduces the Phase One Aerial System 150, a next generation fully integrated fully digital aerial camera system with one single digital camera head and lens which almost matches the perfect geometry of a film camera for all airborne mapping ...
M. M. R. Mostafa, J. Hutton, S. Sobol, L. Viveros, S. Cooper, Y. Raizman   +5 more
doaj   +1 more source

MOSY: A method for synthetic opinions to yield a robust fuzzy expert system

MethodsX, 2023
In many domains, decision-making is challenging, as experts are often limited in availability. However, without a sufficient number of expert opinions, the associated solutions would not be robust. Motivated by this, MOSY, a Method for SYnthetic Opinions
N. Gnaneshwara, B.V. Vijay
doaj   +1 more source

Bromocriptine, a Dopamine (D2 ) Receptor Agonist, Used Alone and in Combination with Glipizide in Sub–Therapeutic Doses to Ameliorate Hyperglycaemia [PDF]

Journal of Clinical and Diagnostic Research, 2013
Introduction: Bromocriptine, an ergot derivative, is an agonist at the dopamine 2 receptor and a sympatholytic. It is a well established drug in Parkinsonism, hyperprolactinaemia and acromegaly and it has various other clinical indications like ...
Harish Kumar V.S., Vinutha M.B., Pradeep A.N., Sathisha Aithal, Sindhura Reddy Baleed, Umakant N. Patil   +5 more
doaj   +1 more source

Effects of swift heavy ion-irradiation on magnetic properties of Co-doped TiO2

AIP Advances, 2021
Ferromagnetic Co-doped TiO2 thin films at room temperature have been synthesized by RF sputtering and ion-irradiated with 100 MeV Au ions. The surface roughness of the film increases with increasing Au-ion fluence.
S. R. Kumar, D. M. Phase, Ajay Gupta, A. C. Pandey, Ratnesh Gupta   +4 more
doaj   +1 more source

Neoepitope load, T cell signatures and PD-L2 as combined biomarker strategy for response to checkpoint inhibition immunotherapy

Frontiers in Genetics, 2023
Immune checkpoint inhibition for the treatment of cancer has provided a breakthrough in oncology, and several new checkpoint inhibition pathways are currently being investigated regarding their potential to provide additional clinical benefit.
Annie Borch, Anne-Mette Bjerregaard, Anne-Mette Bjerregaard, Vinicius Araujo Barbosa de Lima, Olga Østrup, Christina Westmose Yde, Aron Charles Eklund, Morten Mau-Sørensen, Carolina Barra, Inge Marie Svane, Finn Cilius Nielsen, Finn Cilius Nielsen, Samuel A. Funt, Ulrik Lassen, Sine Reker Hadrup   +14 more
doaj   +1 more source

The NUCKS1-SKP2-p21/p27 axis controls S phase entry

Nature Communications, 2021
Entry into S phase of the cell cycle is regulated positively by mitogens and negatively by DNA damage; however, how balance of these signals is achieved is not well known.
Samuel Hume, Claudia P. Grou, Pauline Lascaux, Vincenzo D’Angiolella, Arnaud J. Legrand, Kristijan Ramadan, Grigory L. Dianov   +6 more
doaj   +1 more source

Regulation in S Phase by E2F [PDF]

Cell Cycle, 2004
The DNA synthetic S phase of the unperturbed cell cycle is a closed system, as compared to regulation of G(1) by external growth factors. The E2F family provides internal control in S phase by transcribing genes required for deoxynucleotide triphosphate (dNTP) and DNA synthesis.
Arthur B, Pardee, Chiang J, Li, G Prem Veer, Reddy   +2 more
openaire   +2 more sources