Results 1 to 10 of about 3,196,686 (255)
S-phase cancer associated lncRNAs [PDF]
Comment on: Ali MM, et al. Nature Communications 2018; 9:883.
Santhilal Subhash +2 more
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S‐Phase phosphorylation of lamin B2 [PDF]
Lamin B2 modification in synchronously dividing populations of human diploid fibroblasts was determined by 2‐dimensional gel electrophoresis and [32P]orthophosphate labelling. In quiescent (G0) and G1 cultures of HDF, lamin B2 migrated as 2 spots on 2‐dimensional gels.
Kill, Ian R., Hutchison, Christopher J.
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Developing S-phase control [PDF]
The duration of S phase in early embryos is often short, and then increases as development proceeds because of the appearance of late-replicating regions of the genome. In the April 1, 2012, issue of Genes & Development, Farrell and colleagues (pp.
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S-phase against S-phase tribopairs for biomedical applications
Abstract S-phase, or expanded austenite, is a corrosion resistant diffused hardened layer which can be created in austenitic stainless steels and cobalt–chromium(Co-Cr) alloys. It is a precipitate-free metastable supersaturated solid solution of nitrogen or carbon or both.
Buhagiar, Joseph P. +4 more
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The S phase checkpoint protects the genome from spontaneous damage during DNA replication, although the cause of damage has been unknown. We used a dominant-negative mutant of a subunit of CAF-I, a complex that assembles newly synthesized DNA into nucleosomes, to inhibit S phase chromatin assembly and found that this induced S phase arrest.
Ye, Xiaofen +5 more
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Cdk1: Unsung Hero of S Phase? [PDF]
Cdk2 has been viewed as a key cell cycle regulator that is essential for S phase progression. The recent discovery that Cdk2 is not required for cell proliferation in mice now shows that other factors must be able to replace Cdk2 in stimulating DNA replication.
Marcin, Pacek +2 more
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Regulation in S Phase by E2F [PDF]
The DNA synthetic S phase of the unperturbed cell cycle is a closed system, as compared to regulation of G(1) by external growth factors. The E2F family provides internal control in S phase by transcribing genes required for deoxynucleotide triphosphate (dNTP) and DNA synthesis.
Arthur B, Pardee +2 more
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ORC and the intra-S-phase checkpoint: a threshold regulates Rad53p activation in S phase [PDF]
The intra-S-phase checkpoint in yeast responds to stalled replication forks by activating the ATM-like kinase Mec1 and the CHK2-related kinase Rad53, which in turn inhibit spindle elongation and late origin firing and lead to a stabilization of DNA polymerases at arrested forks.
Kenji, Shimada +2 more
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Setting the Stage for S Phase [PDF]
In a recent issue of Molecular Cell, Tyagi et al. (2007) show that E2F1, a positive regulator of S phase entry, recruits cofactor HCF-1 and associated hSet1/MLL histone H3 lysine 4 methyltransferase complex, facilitating the activation of genes required for proliferation.
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SnapShot: S-Phase Entry and Exit
S-phase entry and exit are regulated by hundreds of protein complexes that assemble "just in time," orchestrated by a multitude of distinct events. To help understand their interplay, we have created a tailored visualization based on the Minardo layout, highlighting over 80 essential events.
Burgess, Andrew +5 more
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