Results 61 to 70 of about 131,599 (329)

Unmasking adenoid cystic carcinoma on lip mimicking as reactive lesion – A case report and review of literature

open access: yesSRM Journal of Research in Dental Sciences
Rationale: Among salivary gland malignancies, adenoid cystic carcinoma (ADCC) is a particularly uncommon entity in the lip region, representing approximately 1% of malignant neoplasms in the head and neck.
Akalya Purushothaman   +4 more
doaj   +1 more source

Extracellular S100β Disrupts Bergman Glia Morphology and Synaptic Transmission in Cerebellar Purkinje Cells

open access: yesBrain Sciences, 2019
Astrogliosis is a pathological process that affects the density, morphology, and function of astrocytes. It is a common feature of brain trauma, autoimmune diseases, and neurodegeneration including spinocerebellar ataxia type 1 (SCA1), a poorly ...
Olga S. Belozor   +7 more
doaj   +1 more source

Speed limit to the Abrikosov lattice in mesoscopic superconductors [PDF]

open access: yes, 2015
We study the instability of the superconducting state in a mesoscopic geometry for the low pinning material Mo$_3$Ge characterized by a large Ginzburg-Landau parameter.
Carapella, G.   +7 more
core   +1 more source

S100 proteins in cardiovascular diseases

open access: yesMolecular Medicine, 2023
AbstractCardiovascular diseases have become a serious threat to human health and life worldwide and have the highest fatality rate. Therefore, the prevention and treatment of cardiovascular diseases have become a focus for public health experts.
Yue Zhou   +5 more
openaire   +3 more sources

Neuid: A Novel Neuron‐Enriched LncRNA that Connects Epigenetic Gene Silencing to Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
ABSTRACT The increasing evidence that non‐coding RNAs can become deregulated during pathogenesis is dramatically expanding the space for drug discovery beyond the protein‐coding genome. Long noncoding RNAs (lncRNAs) are emerging as key regulators of cellular function, yet most remain uncharacterized.
Ranjit Pradhan   +17 more
wiley   +1 more source

S100 Proteins in Acute Myeloid Leukemia

open access: yesNeoplasia: An International Journal for Oncology Research, 2018
The S100 protein family contains 20 functionally expressed members, which are commonly dysregulated in cancer. Their wide range of functions includes cell proliferation, cell differentiation, regulation of transcription factors, inflammation, chemotaxis,
Annette K. Brenner, Øystein Bruserud
doaj   +1 more source

Multiple Evolutionary Origins of Ubiquitous Cu2+ and Zn2+ Binding in the S100 Protein Family. [PDF]

open access: yesPLoS ONE, 2016
The S100 proteins are a large family of signaling proteins that play critical roles in biology and disease. Many S100 proteins bind Zn2+, Cu2+, and/or Mn2+ as part of their biological functions; however, the evolutionary origins of binding remain obscure.
Lucas C Wheeler   +3 more
doaj   +1 more source

Optical Spectroscopy of Galactic Cirrus Clouds: Extended Red Emission in the Diffuse Interstellar Medium [PDF]

open access: yes, 1997
We present initial results from the first optical spectroscopic survey of high latitude Galactic cirrus clouds. The observed shape of the cirrus spectrum does not agree with that of scattered ambient Galactic starlight.
Arpad Szomoru   +19 more
core   +3 more sources

Deciphering and Targeting the Schwannoma‐Neuron‐Macrophage Crosstalk for the Treatment of Schwannomatosis and Associated Pain

open access: yesAdvanced Science, EarlyView.
We established patient‐derived SWN cell lines and orthotopic PDX models that recapitulate patient pain phenotypes, alongside a novel intravital DRG imaging platform to track macrophage infiltration and neuronal pain responses. Using these models, we define HMGB1–CCL2–IL‐6 signaling crosstalk driving pain and identify EGF signaling as a key regulator of
Zhenzhen Yin   +17 more
wiley   +1 more source

A Study to Delineate the Immunohistological Parameters of Active Versus Stable Vitiligo Using S100, Melan A in Conjunction with CD4 and CD8 Immunohistochemistry Markers

open access: yesIndian Dermatology Online Journal
Background: Vitiligo is an autoimmune pigmentary disorder where it is important to assess the disease status (active/stable) to guide therapeutic decisions.
Sai Jyoti   +4 more
doaj   +1 more source

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