Results 31 to 40 of about 6,571,656 (224)

Significance of Elecsys (R) S100 immunoassay for real-time assessment of traumatic brain damage in multiple trauma patients [PDF]

, 2006
Background: The neuroprotein S100 released into the circulation has been suggested as a reliable marker for primary brain damage. However, safe identification of relevant traumatic brain injury (TBI) may possibly be hampered by S100 release from ...
Kirchhoff, Chlodwig, Gippner-Steppert, Cornelia, Mussack, Thomas, Buhmann, Sonja, Jochum, Marianne, Ladurner, Roland, Biberthaler, Peter, Mutschler, Wolf   +7 more
core   +1 more source

Certainty of S100 from Physiology to Pathology [PDF]

Journal of Clinical and Diagnostic Research, 2016
S100 exists in wide variety of tissues and cell types, originally isolated from brain tissue and they are of low molecular weight proteins. S100 is evenly distributed in cytoplasm and also in nucleoplasm and is involved in both intercellular and ...
Puneeth Horatti Kuberappa, Bhavana Shivanand Bagalad, Anuradha Ananthaneni, Md Asif Kiresur, Guduru Vijay Srinivas   +4 more
doaj   +1 more source

Both Ca2+ and Zn2+ are essential for S100A12 protein oligomerization and function [PDF]

, 2009
Background Human S100A12 is a member of the S100 family of EF-hand calcium-modulated proteins that are associated with many diseases including cancer, chronic inflammation and neurological disorders.
Lednev, Igor K., Helmut Wittkowski, Anatoli Ianoul, Igor B Bronstein, Shekhtman, Alexander, Bjoerk, Per, Alexander Shekhtman, Per Bjoerk, Foell, Dirk, Wei He, Igor K Lednev, Olga V Moroz, He, Wei, Burkitt, William I., Xie, Jingjing, Derrick, Peter J., Bronstein, Igor B., Vera Novitskaya, Polyakova, Oxana, Ianoul, Anatoli, Dirk Foell, Will Burkitt, Oxana Polyakova, Moroz, Olga V., Peter J Derrick, Wittkowski, Helmut, Novitskaya, Vera, Jingjing Xie   +27 more
core   +1 more source

Participation of the oviductal s100 calcium binding protein G in the genomic effect of estradiol that accelerates oviductal embryo transport in mated rats

Reproductive Biology and Endocrinology, 2011
Background Mating changes the mechanism by which E2 regulates oviductal egg transport, from a non-genomic to a genomic mode. Previously, we found that E2 increased the expression of several genes in the oviduct of mated rats, but not in unmated rats ...
Croxatto Horacio B, Velásquez Luis A, Parada-Bustamante Alexis, Ríos Mariana, Orihuela Pedro A   +4 more
doaj   +1 more source

S100 Proteins in the Pathogenesis of Psoriasis and Atopic Dermatitis

Diagnostics, 2023
The skin, the outermost layer of the human body, is exposed to various external stimuli that cause inflammatory skin reactions. These external stimulants trigger external epithelial cell damage and the release of intracellular substances.
Natsuko Saito-Sasaki, Yu Sawada
doaj   +1 more source

Granular Cell Tumour Masquerading as Carcinoma Breast [PDF]

Journal of Clinical and Diagnostic Research, 2020
Granular Cell Tumour (GCT) is a rare benign tumour that affects head and neck, the most frequent site being the tongue. GCT with localisation to breast is very rare with an incidence of 4-6%. It is an uncommon cause of breast mass in premenopausal women.
Sadiya Shafi, Charles Mano Sylus, Salapathi Shanmugam, P Darwin   +3 more
doaj   +1 more source

Dissecting novel regulatory mechanisms of S100A1 on cardiac function [PDF]

, 2007
6.1 Extracellular S100A1 inhibits apoptosis in ventricular cardiomyocytes: via activation of the extracellular signal-regulated protein kinase 1/2 (ERK1/2) Growing evidence indicates that members of the S100 protein family exert intracellular but ...
Börries, Melanie
core   +1 more source

A Distinct Malignant Epithelioid Neoplasm with GLI1 Gene Rearrangements, Frequent S100 Protein Expression and Metastatic Potential: Expanding the Spectrum of Pathologic Entities with ACTB1/MALAT1/PTCH1-GLI1 Fusions

American Journal of Surgical Pathology, 2018
ACTB-GLI1 fusions have been reported as the pathognomonic genetic abnormality defining an unusual subset of actin-positive, perivascular myoid tumors, known as “pericytoma with the t(7;12) translocation.” In addition, GLI1 oncogenic activation through a ...
C. Antonescu, N. Agaram, Yun‐Shao Sung, Lei Zhang, D. Swanson, B. Dickson   +5 more
semanticscholar   +1 more source

High throughput competitive fluorescence polarization assay reveals functional redundancy in the S100 protein family

bioRxiv, 2019
The calcium-binding, vertebrate-specific S100 protein family consists of 20 paralogs in humans (referred as the S100ome), with several clinically important members. To assess their interactome, high-throughput, systematic analysis is indispensable, which
Márton A. Simon, Péter Ecsédi, G. Kovács, Á. Póti, A. Reményi, J. Kardos, G. Gógl, L. Nyitray   +7 more
semanticscholar   +1 more source

S100 Protein Family and Tumorigenesis [PDF]

, 2011
Deep insight on S100 Protein Family and ...
Freeze, HH, Srikrishna, G
core   +1 more source