Results 21 to 30 of about 6,571,656 (224)
Microscopy Research and Technique, 2008 S100 proteins are EF-hand calcium-binding protein highly preserved during evolution present in both neuronal and non-neuronal tissues of the higher vertebrates.
A Germana +2 more
exaly +1 more source
Role of the S100 protein family in liver disease (Review).
International Journal of Molecular Medicine, 2021 Liver disease is a significant health challenge worldwide and comprises liver fibrosis and cirrhosis, viral hepatitis, fatty liver, non‑alcoholic fatty liver disease, alcoholic liver disease and hepatocellular carcinoma (HCC).
S. Yao +6 more
semanticscholar +1 more source
Nature Reviews Cancer, 2015 In humans, the S100 protein family is composed of 21 members that exhibit a high degree of structural similarity, but are not functionally interchangeable. This family of proteins modulates cellular responses by functioning both as intracellular Ca(2+) sensors and as extracellular factors.
Anne R, Bresnick +2 more
openaire +2 more sources
S100 as Serum Tumor Marker in Advanced Uveal Melanoma
Biomolecules, 2023 S100 protein is routinely used as a serum tumor marker in advanced cutaneous melanoma. However, there is scarce and inconclusive evidence on its value in monitoring disease progression of uveal melanoma.
Martin Salzmann +2 more
doaj +1 more source
Localisation of S100 Protein and Acetylated Tubulin in Sheep Pancreas
Folia Veterinaria, 2021 The pancreas plays a critical role in the control of nutritional homeostasis. It consists of two major parts, the exocrine pancreas, and the endocrine pancreas.
Marettová E., Maretta M.
doaj +1 more source
S100 Proteins in the Epidermis [PDF]
Journal of Investigative Dermatology, 2004 The S100 proteins comprise a family of 21 low molecular weight (9-13 kDa) proteins that are characterized by the presence of two calcium-binding EF-hand motifs. Fourteen S100 protein genes are located within the epidermal differentiation complex on human chromosome 1q21 and 13 S100 proteins (S100A2, S100A3, S100A4, S100A6, S100A7, S100A8, S100A9 ...
Eckert, Richard L. +5 more
openaire +2 more sources
S100s and HMGB1 Crosstalk in Pancreatic Cancer Tumors
Biomolecules, 2023 Pancreatic cancer remains a disease that is very difficult to treat. S100 proteins are small calcium binding proteins with diverse intra- and extracellular functions that modulate different aspects of tumorigenesis, including tumor growth and metastasis.
Angelo Mandarino +5 more
doaj +1 more source
S100 proteins in cardiovascular diseases
Molecular Medicine, 2023 AbstractCardiovascular diseases have become a serious threat to human health and life worldwide and have the highest fatality rate. Therefore, the prevention and treatment of cardiovascular diseases have become a focus for public health experts.
Yue Zhou +5 more
openaire +3 more sources
S100A6 protein negatively regulates CacyBP/SIP-mediated inhibition of gastric cancer cell proliferation and tumorigenesis. [PDF]
PLoS ONE, 2012 Calcyclin-binding protein (CacyBP/SIP), identified on the basis of its ability to interact with S100 proteins in a calcium-dependent manner, was previously found to inhibit the proliferation and tumorigenesis of gastric cancer cells in our laboratory ...
Xiaoxuan Ning +6 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2021 Despite several new therapeutic options, multiple myeloma (MM) patients experience multiple relapses and inevitably become refractory to treatment. Insights into drug resistance mechanisms may lead to the development of novel treatment strategies.
Minxia Liu +16 more
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