Results 81 to 90 of about 29,623 (214)

The role of fecal calprotectin in pediatric disease [PDF]

Korean Journal of Pediatrics, 2019
Fecal calprotectin (FC) is a calcium- and zinc-binding protein of the S100 family, mainly expressed by neutrophils and released during inflammation. FC became an increasingly useful tool both for gastroenterologists and for general practitioners for ...
Su Jin Jeong
doaj   +1 more source

Establishment of Salivary Gland Tumors Arising in Salivary Gland‐Specific EWSR1::ATF1 Transgenic Mice

Head &Neck, EarlyView.
ABSTRACT Background Salivary gland carcinomas are uncommon malignancies with various histological subtypes harboring fusion genes. The EWSR1::ATF1 fusion gene, resulting from a translocation between chromosomes 12 and 22, is frequently observed in hyalinizing clear cell carcinoma (HCCC). However, the role of this fusion gene in HCCC oncogenesis remains
Yuri Hirai, Yoshitaka Utsumi, Daisuke Sano, Tatsu Kuwahara, Yoshihiro Aizawa, Takashi Hatano, Hisashi Hasumi, Yutaro Soejima, Tatsukata Kawagoe, Ryosuke Jikuya, Nobuhisa Mizuki, Satoshi Fujii, Toshitaka Nagao, Nobuhiko Oridate   +13 more
wiley   +1 more source

The S100B Protein in Epilepsy

Archives of Epilepsy, 2023
Epilepsy is a chronic disease caused by an increased excitability of nerve cells in the brain, characterized by two or more unprovoked seizures, which can be attributed to genetic or acquired causes.
Ahmet Eren Seçen, Didem Tuba Akçalı, Gökhan Kurt   +2 more
doaj   +1 more source

High‐throughput competitive fluorescence polarization assay reveals functional redundancy in the S100 protein family

, 2020
International audienceThe calcium-binding, vertebrate-specific S100 protein family consists of 20 paralogs in humans (referred as the S100ome), with several clinically important members. To explore their protein-protein interactions (PPIs) quantitatively,
Simon, Márton A., Kardos, József, Ecsédi, Péter, Kovacs, Gabor, M., Nyitray, László, Gógl, Gergő, Póti, Adam L., Reményi, Attila   +7 more
core   +1 more source

Annexin I and Annexin II N-Terminal Peptides Binding to S100 Protein Family Members: Specificity and Thermodynamic Characterization

, 2016
The S100 proteins make up a family of dimeric calcium binding proteins that function in response to changing calcium levels. Several S100 binding proteins have been identified; however, the exact biological functions of the S100 proteins are largely ...
Werner W. Streicher (742888), Maria M. Lopez (2384047), George I. Makhatadze (155655)   +2 more
core   +1 more source

Effect of Human S100A13 Gene Silencing on FGF-1 Transportation in Human Endothelial Cells

Journal of the Formosan Medical Association, 2010
The S100 protein is part of a Ca2+ binding protein superfamily that contains an EF hand domain, which is involved in the onset and progression of many human diseases, especially the proliferation and metastasis of tumors.
Renxian Cao, Bin Yan, Huiling Yang, Xuyu Zu, Gebo Wen, Jing Zhong   +5 more
doaj   +1 more source

S100A9 promotes pulmonary arterial hypertension by regulating mitochondria–endoplasmic reticulum interaction‐mediated inflammatory injury of endothelial cells

Interdisciplinary Medicine, EarlyView.
Macrophage‐derived S100 calcium‐binding protein A9 (S100A9) promotes the pathological progression of pulmonary arterial hypertension (PAH). S100A9 upregulates the interaction between signal‐transducing adaptor protein 2 and leucine‐rich repeat kinase 2, thereby regulating mitochondria–endoplasmic reticulum (ER) contact.
Chen Gong, Long Chen, Yiting Zhao, Xiaohe Wang, Qiang Yuan, Xiaofeng Fang, Liuyi Li, Yinbo Xu, Shumei Jiang, Guangwen Xu, Ke Meng, Delong Wang, Kangli Cao, Jianlong Sheng, Liling Guo, Shichun Shen   +15 more
wiley   +1 more source

Integrative approaches to protein homology search

, 2005
Alam I. Integrative approaches to protein homology search. Bielefeld (Germany): Bielefeld University; 2005.Many methods have been developed to search for homologous members of a protein family in databases, and the reliability of results and conclusions ...
Alam, Intikhab
core  

A model for target protein binding to calcium-activated S100 dimers

, 1998
S100 proteins are a family of dimeric calcium-binding proteins implicated in several cancers and neurological diseases. Calbindin D9k is an unusual monomeric member of the S100 family.
Kuźnicki, Jacek, Finn, Bryan E, Jacek Kuźnicki, Patrick Groves, Forsén, Sture, Bryan E Finn, Sture Forsén, Groves, Patrick   +7 more
core   +1 more source

Calcium Binding Proteins] [PDF]

Türk Biyokimya Dergisi, 2006
Calcium ions are essentail for some of the cellular functions, including musclecontraction, adhesion, secretion, motility, growth, differentiation, gene expression,and cell death.
Berivan Tandoğan, N. Nuray Ulusu
doaj