Results 131 to 140 of about 48,304 (243)
ATP1B2 and GLAST identify two astrocyte subpopulations in the hippocampus with distinct molecular signatures. Transcriptomic shifts during aging differ between both subpopulations. Aged ATP1B2+ astrocytes rewire their metabolism while double‐positive aged astrocytes display a reduced synaptogenic capability.
Lucía Casares‐Crespo +6 more
wiley +1 more source
Human Cortical Neural Progenitor Cells
Cell Proliferation, EarlyView.
An‐Xin Wang +29 more
wiley +1 more source
Novel NaV1.6‐Mitochondrial Complexes in Retinal Astrocyte Pockets Sequester GABA
NaV1.6 localizes in retinal astrocytes' high density pockets on the bilayer facing the ganglion cell layer. NaV colocalizes with large, anaplerotic mitochondria. These microdomains accumulate high levels of GABA. ABSTRACT Voltage‐gated sodium channels are best known for their capacity to generate and propagate electrical currents in neurons and muscle.
Joseph Matthew Holden +1 more
wiley +1 more source
Human health is seriously endangered by spontaneous intracerebral hemorrhage (ICH) and aneurysmal subarachnoid hemorrhage (aSAH). Because the majority of ICH and aSAH survivors experience disability, increased risk of stroke recurrence, cognitive decline,
Zhang-Ming Zhou +3 more
doaj +1 more source
Molekulare Mechanismen der S100B-vermittelten Neuroprotektion [PDF]
Im Rahmen dieser Arbeit wurde die Rolle des Proteins S100B in humanen Neuroblastomzellen und primären hippokampalen Neurone der Ratte beim apoptotischen Zelltod untersucht.
Hashemi, Seyed Mohammad Amin
core
Cell type–specific EVs were isolated from mouse brain and profiled by proteomics. Each EV subtype exhibited proteomic signatures consistent with the specialized functions of its cell of origin. Astrocyte‐derived EVs (ADEVs) were enriched for the GlialCAM/MLC1 network and GPCRs.
Alba M. Lucart‐Sanchez +7 more
wiley +1 more source
Injection (exogenous) strategies demonstrate privilege of barrier organs to transendothelial diffusion of S100B while immunodetection of endogenous S100B demonstrates brain- and testis specific S100B protein by astrocytes and Sertoli cells.
Philip Iffland (591857) +11 more
core +1 more source
Fibro‐Adipogenic Progenitor Ablation Triggers Muscle Atrophy Through Cell Death‐Induced Inflammation
ABSTRACT Background Skeletal muscle mass maintenance involves coordination of myofibers with mononuclear cell populations, including satellite cells, resident macrophages and fibro‐adipogenic progenitors (FAPs). FAPs, identified by surface expression of PDGFRα, are important contributors to muscle homeostasis, as genetic ablation of FAPs induces rapid ...
Yangyi E. Luo +5 more
wiley +1 more source
SOX10 and S100B in Schwann cells
Figure 1. Expression pattern of Sox10 and other differentiation markers in Schwann cells. (A and B) Comparison of expression level between Sox10 and Sox9 in primary rat sciatic nerve Schwann cells and primary rat rib chondrocytes. (C) Time course of mRNA
Toru Ogata (649001) +8 more
core +1 more source
Single‐cell and spatial transcriptomic profiling of 69 adult‐type diffuse gliomas revealed seven recurrent malignant cell states. GBMs were enriched for astrocyte‐like progenitor, hypoxic, and proliferative states, with higher T‐ and myeloid‐cell infiltration but transcriptional immune suppression.
Ashraf Zaman +14 more
wiley +1 more source

