Results 121 to 130 of about 48,304 (243)

Pharmacological Targets for Periodontitis: A Systematic Review of Drug‐Target Mendelian Randomisation Studies

open access: yesJournal of Periodontal Research, EarlyView.
This systematic review evaluated drug‐target Mendelian randomisation studies on periodontitis. Twelve studies identified host‐response‐related targets mainly involved in inflammatory, complement, and immune pathways. Although some targets were linked to existing drugs, the evidence remains preliminary and heterogeneous, requiring replication and ...
Luigi Nibali   +4 more
wiley   +1 more source

S100B-proteiini lasten kuumekouristuksissa

open access: yes, 2014
S100B-proteiini on gliasoluspesifinen proteiini, jota vapautuu verenkiertoon aivovaurioiden yhteydessä. Kohonneet pitoisuudet korreloivat aivovaurion vaikeusasteen ja lopputuleman kanssa.
Pekkala, N. (Niina)
core  

S100B is present in CNV lesions.

open access: yes, 2014
A) S100B expression in a normal WT mouse retina. Strong immunoreactivity is present in the astrocytes (arrow). The position of the inner nuclear layer (INL) and outer nuclear layer (ONL) are indicted.
Josephine V. Glenn (30762)   +9 more
core   +1 more source

Thermoregulatory and plasma neurobiomarker responses to heat tolerance assessment in exertional heat illness and matched controls

open access: yesExperimental Physiology, EarlyView.
Abstract Exercise in the heat and elevated tissue temperature are associated with neuronal stress and changes in blood–brain barrier (BBB) function. More severe thermal insult may manifest as exertional heat illness (EHI) and complication by central nervous system (CNS) dysfunction may persist post‐EHI.
Tom W. Palin   +15 more
wiley   +1 more source

Biological Markers in Newly Diagnosed Generalized Anxiety Disorder Patients: 8-OHdG, S100B and Oxidative Stress

open access: yesNeuropsychiatric Disease and Treatment
Meltem Oktay,1 Mehmet Asoğlu,2 Seyhan Taskin,3 Adnan Kirmit4 1Department of Psychiatry, Istanbul Training and Research Hospital, Istanbul, Turkey; 2Department of Psychiatry, Faculty of Medicine, Harran University, Sanliurfa, Turkey; 3Department of
Oktay M, Asoğlu M, Taskin S, Kirmit A
doaj  

Synchrony within Aβ mechanoreceptor subtypes governs signal propagation to primary somatosensory cortex

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend We used an optogenetic gain‐of‐function manipulation to investigate how sensory signals from two subtypes of Aβ low threshold mechanoreceptors (LTMRs) contribute to the cortical representation of touch. CatCh, a sensitive and fast channelrhodopsin variant, enables pulsed‐light generation of high‐frequency action potential trains ...
Wanyi Liu   +2 more
wiley   +1 more source

S100B protein expression in the heart of deceased individuals by overdose: a new forensic marker?

open access: yesClinics
OBJECTIVE: The evaluation of S100B protein expression in the human heart and its correlation with drug-related death. METHOD: Left ventricular samples were collected from 74 serial forensic autopsies (15 overdose-related deaths; 59 non-overdose-related ...
Armando Faa   +7 more
doaj   +1 more source

Molecular Control of Neural Stem Cell Quiescence in the Adult Zebrafish Telencephalon: Established Mechanisms and an Integrative Hypothesis

open access: yesGlia, Volume 74, Issue 12, December 2026.
Adult zebrafish radial glia quiescence is controlled by at least four mechanisms: Notch3, BMP‐Id1, Nr2f1b and Midkine‐a. We propose these act as partially redundant inputs, biased along the antero‐posterior axis that set quiescence depth. ABSTRACT The zebrafish telencephalon is an excellent model for adult neurogenesis under physiological and ...
Mathilde Hoareau   +2 more
wiley   +1 more source

Beneficial Role of Natural Polyphenols Against Epilepsy: Greasing the Wheels of Pharmacotherapy Research for Epilepsy

open access: yesFood Frontiers, Volume 7, Issue 6, November 2026.
ABSTRACT Epilepsy is the most disabling neurological disease that affects all economic classes, age groups, regions, and races. Although many antiseizure drugs are approved for epilepsy treatment, they fail to work in about 30%–40% of patients. Thus, there is a great need to identify better pharmacological agents to treat epilepsy.
Janakiraman Pillai Udaiyappan   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy