Results 101 to 110 of about 48,304 (243)
The Enteric Nervous System: An Integrative Hub From Development to Systemic Physiology
Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.Unlike a static hardwired circuit, the ENS continuously remodels its transcriptional programs and synaptic connectivity in response to three ecological forces: microbial metabolites, immune cell signals and enteroendocrine cues. ABSTRACT The enteric nervous system (ENS) constitutes the largest and most functionally autonomous subdivision of the ...
Mario Cuchillo‐Hilario +3 more
wiley +1 more source
Journal of Investigative Surgery, 2020 Objective: To evaluate the effects of isolated impaired fasting glucose (IIFG) on brain injury in patients undergoing cardiopulmonary bypass (CPB) surgery.
Tao Zhou +3 more
doaj +1 more source
Target S100B to reduce Experimental Autoimmune Encephalomyelitis pathogenesis
, 2018 Tese de mestrado, Ciências Biofarmacêuticas, Universidade de Lisboa, Faculdade de Farmácia, 2018Multiple Sclerosis (MS) is a complex chronic immune disease in the central nervous system (CNS), causing neurological disability in young people aged between
Barros, Catarina da Silva
core
The Predictive Role of Neurobiochemical Markers in Multiple Sclerosis
İstanbul Medical Journal, 2020 Introduction:Multiple sclerosis (MS) is the most common, chronic, inflammatory, demyelinating disease of the central nervous system. We aimed to evaluate the levels of some neurobiochemical markers in order to evaluate their predictive role in MS.Methods:
Esra Fırat Oğuz +4 more
doaj +1 more source
Interação da proteína S100B com fibrilas ß amiloides : possível papel desagregante da S100B in vitro [PDF]
, 2022 A doença de Alzheimer é o tipo de demência com a maior prevalência na população idosa, afetando drasticamente a memória e a autonomia dos indivíduos acometidos.
Federhen, Bárbara Carolina
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S100B: Correlation with Active Vitiligo Depigmentation [PDF]
Journal of Investigative Dermatology, 2017 Vitiligo, the most common depigmenting disorder, is caused by immune destruction of melanocytes by cytotoxic CD8+ T cells. One weakness in vitiligo management is the lack of an assessment method for active depigmentation. Beginning with reports about increased S100B levels in different inflammatory and tissue damage processes, Speeckaert et al ...
openaire +2 more sources
The Journal of Pathology, EarlyView.Abstract Propionic acidemia (PA) is a neurometabolic disorder caused by propionyl‐CoA carboxylase deficiency with frequent neurological involvement, yet cell‐type‐specific mechanisms remain poorly defined. We established human induced pluripotent stem cell (iPSC)‐derived astrocytes (iAs) from patients harboring PCCA or PCCB mutations and investigated ...
Irene González‐Garnacho +5 more
wiley +1 more source
S100B protein, astrocytes and memory [PDF]
, 2008 S100 is a vertebrate-specific family of small, calcium-binding proteins. One of them is the S100B protein, mostly expressed in, and released by astroglial cells in the brain.
Sołtys, Zbigniew, Kiełbiński, Michał
core +1 more source
Microglia Ablation and Downstream Effects in the Cerebrospinal Fluid Proteome
PROTEOMICS, EarlyView.ABSTRACT Disease‐related activation of glial cells leads to changes in the cerebrospinal fluid (CSF) proteome. However, assigning such protein changes to their cellular origins is often difficult. Here, we used microglia (and macrophage) depletion in mice to identify CSF proteins of microglial origin.
Sinja Buchner +8 more
wiley +1 more source
MiRNA-Mediated Regulation of S100B: A Review
NeuroSciS100β is a significant signaling molecule and biomarker that is primarily expressed in the brain. At low physiological concentrations, S100β induces astrocyte maturation, microglial migration, and neural proliferation. However, high concentrations activate inflammatory and pro-apoptotic pathways.
Animesh Dali +3 more
openaire +2 more sources