S100B Secretion in Astrocytes, Unlike C6 Glioma Cells, Is Downregulated by Lactate
S100B is a calcium-binding protein produced and secreted by astrocytes in response to various extracellular stimuli. C6 glioma cells are a lineage commonly employed for astroglial studies due to the expression of astrocyte specific markers and behavior ...
Nicholas Guerini Selistre +6 more
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S100 Calcium-Binding Protein B and Glial Fibrillary Acidic Protein in Patients with Mild Traumatic Brain Injury [PDF]
Objective: To examine the GFAP and S100B ability in prevention unnecessary brain CT scan in mTBI and compare them with the single extremity fracture in orthopedic patients.
Ali Meshkini +3 more
doaj +1 more source
Diagnostic and predictive value of aEEG in newborns in critical state under sedation
The objective: to study the diagnostic and prognostic value of amplitude-integrated electroencephalography (aEEG) in sedated neonates in critical state, through testing the level of S100B protein.
A. A. Zadvornov, E. V. Grigoriev
doaj +1 more source
Elevated Blood S100B Levels in Patients With Migraine: A Systematic Review and Meta-Analysis
Background:In recent years, a growing number of researches indicate that S100B may act in migraine, but the relationship between S100B and migraine remains controversial.
Chaojia Chu +4 more
doaj +1 more source
Comparison of physiological state and conditions imitating the comorbidity of type 2 diabetes with Alzheimer's disease. The impact on: proliferation, H2O2, Aβ42, S100A8, S100B levels, neuronal protrusion and neurogenesis [PDF]
Aim: Recent studies demonstrate that individuals with T2DM more likely to develop AD. While, disturbed glucose or insulin homeostasis, are at the forefront of AD research, not much is known about extra- and intracellular interplay between different forms
Adriana Kubis-Kubiak +2 more
doaj +1 more source
Association of S100B polymorphisms and serum S100B with risk of systemic lupus erythematous in a Chinese population [PDF]
The aim of this study was to investigate whether the S100B polymorphisms are associated with systemic lupus erythematous (SLE) in a Chinese population. A total of 313 SLE patients and 396 control subjects were enrolled in the present study. The genotypes of three SNPs (rs9722, rs881827 and rs1051169) in S100B gene were detected by single base extension
Yulan Lu +7 more
openaire +5 more sources
S100B is an astrocytic protein acting either as an intracellular regulator or an extracellular signaling molecule. A direct correlation between increased amount of S100B and demyelination and inflammatory processes has been demonstrated.
Gabriele Di Sante +8 more
doaj +1 more source
Astrocyte specific proteins content in the different parts of the rat and mongolian gerbil brain during ontogenesis [PDF]
Astrocyte-specific proteins are used as markers of astrocytes, particularly in the case of age-related brain dysfunctions and neurodegenerative disorders.
Y. P. Kovalchuk +2 more
doaj +1 more source
Evidence for a wide extra-astrocytic distribution of S100B in human brain
Background S100B is considered an astrocytic in-situ marker and protein levels in cerebrospinal fluid (CSF) or serum are often used as biomarker for astrocytic damage or dysfunction. However, studies on S100B in the human brain are rare.
Mawrin Christian +7 more
doaj +1 more source
Plasma levels of S100B and neurofilament light chain protein in stress-related mental disorders
The pathophysiological changes underlying stress-related mental disorders remain unclear. However, research suggests that alterations in astrocytes and neurons may be involved.
Johanna Wallensten +6 more
doaj +1 more source

