Results 71 to 80 of about 40,904 (213)

Variability in intracellular localization of D‐amino acid oxidase in choroid plexus epithelial cells

The FEBS Journal, EarlyView.
D‐amino acid oxidase (DAO) in choroid plexus epithelial cells (CPECs) shows vesicle‐like localization by histological and super‐resolution analyses. DAO colocalizes with peroxisomal, Golgi, endosomal, lysosomal, autophagosomal, and exosomal markers, indicating diverse subcellular distribution. This suggests DAO is transported within CPECs to metabolize
Koji Ono, Yuji Shishido, Toshiyuki Yamagishi, Kiyoshi Fukui   +3 more
wiley   +1 more source

Astrocytic Biomarkers in Epilepsy: A Critical Review on Clinical Utility and Mechanistic Implications

Frontiers in Bioscience-Landmark
Epilepsy is one of the most common neurological disorders in both children and adults, characterized by significant clinical heterogeneity and dynamic natural course.
Ting-Rong Hsu, Pei-Hao Chen, Wei-Sheng Lin   +2 more
doaj   +1 more source

A lack of association between elevated serum levels of S100B protein and autoimmunity in autistic children

Journal of Neuroinflammation, 2012
Background S100B is a calcium-binding protein that is produced primarily by astrocytes. Increased serum S100B protein levels reflect neurological damage. Autoimmunity may have a role in the pathogenesis of autism in some patients.
Al-Ayadhi Laila, Mostafa Gehan
doaj   +1 more source

Astrocytic connexin43 phosphorylation contributes to seizure susceptibility after mild traumatic brain injury

The FEBS Journal, EarlyView.
Astrocytic gap junctions formed by connexin43 (Cx43) help maintain brain homeostasis. After mild traumatic brain injury (TBI), total cortical Cx43 increases and redistributes toward a soluble, non‐junctional pool with elevated hemichannel activity and increased phosphorylation at serine 368 (pCx43S368).
Carmen Muñoz‐Ballester, Owen Leitzel, Samantha Golf, Chelsea M. Phillips, Michael J. Zeitz, Rahul Pandit, Elizabeth Wash, Jenna V. Donohue, Elizabeth A. Istre, James W. Smyth, Samy Lamouille, Stefanie Robel   +11 more
wiley   +1 more source

Elevated Plasma Phospho‐Tau217 in Beta‐Propeller Protein‐Associated Neurodegeneration

Movement Disorders, EarlyView.
Jae‐Hyeok Lee, Yun Soo Kim
wiley   +1 more source

Astrocytic mGluR5 Regulation of Synaptic Transmission is Activity‐Dependent in Adult Rats

Glia, Volume 74, Issue 8, August 2026.
In adulthood, astrocytic mGluR5 increases synaptic efficacy through presynaptic A2ARs. This occurs when a small number of synapses are activated simultaneously. This pathway is abolished when numerous synapses are recruited. ABSTRACT Data accumulated over the last two decades have demonstrated that astrocytes play key roles in the regulation of ...
Sarah Mountadem, Muna L. Hilal, Dylan Pommier, Dorian Arnouil, Valentin Clément Langlais, Vincent Simon, Aurélie Amadio, Marie Miegebielle, Sébastien Marais, Charlène Joséphine, Astrid Cannich, Marjorie Varilh, Julien Bourel, Daniela Cota, Giovanni Marsicano, Alexis‐Pierre Bemelmans, Philippe Ciofi, Stéphane Henri Richard Oliet, Aude Panatier   +18 more
wiley   +1 more source

S100B protein as a biomarker and predictor in traumatic brain injury

Biomedical Papers
Objectives. To determine the prognostic potential of S100B protein in patients with craniocerebral injury, correlation between S100B protein and time, selected internal diseases, body habitus, polytrauma, and season. Methods.
Stefan Trnka, Premysl Stejskal, Jakub Jablonsky, David Krahulik, Daniel Pohlodek, Lumir Hrabalek   +5 more
doaj   +1 more source

Lipopolysaccharide modulates astrocytic S100B secretion: a study in cerebrospinal fluid and astrocyte cultures from rats

Journal of Neuroinflammation, 2011
Background Inflammatory responses in brain are primarily mediated by microglia, but growing evidence suggests a crucial importance of astrocytes. S100B, a calcium-binding protein secreted by astrocytes, has properties of a neurotrophic or an inflammatory
Leite Marina C, Rodrigues Letícia, Engelke Douglas S, Negri Elisa, Da Ré Carollina, Galland Fabiana, Tortorelli Lucas S, Guerra Maria, Gonçalves Carlos-Alberto   +8 more
doaj   +1 more source

Sphingosine‐1‐Phosphate Receptor 1 Regulates Competition Dependent Astrocyte Morphogenesis and Tiling in Murine Cortex

Glia, Volume 74, Issue 8, August 2026.
Neuronal contact‐induced expression of S1PR1 in astrocytes is regulated by JAK‐STAT3 signaling. Astrocytic S1PR1 modulates cortical astrocyte morphogenesis. Astrocytic S1PR1 regulates astrocyte territorial overlap/tiling in a competition dependent manner.
Jean Patrick M. Gonzales, Connor Tuck, Surya Chandra Rao Thumu, Soha Munir, Jaden Harris, Hunain (Zeik) Tariq, Paul Marcelli, Oscar Dominguez, Kaviya Suriyakumar Anbazagan, Sandeep K. Singh   +9 more
wiley   +1 more source

Effects of Isolated Impaired Fasting Glucose on Brain Injury During Cardiac Surgery Under Cardiopulmonary Bypass

Journal of Investigative Surgery, 2020
Objective: To evaluate the effects of isolated impaired fasting glucose (IIFG) on brain injury in patients undergoing cardiopulmonary bypass (CPB) surgery.
Tao Zhou, Suining Li, Daokang Xiang, Lufang Gao   +3 more
doaj   +1 more source