Results 41 to 50 of about 3,737,571 (308)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen +23 more
wiley +1 more source
Setting the Stage for S Phase [PDF]
Molecular Cell, 2007 In a recent issue of Molecular Cell, Tyagi et al. (2007) show that E2F1, a positive regulator of S phase entry, recruits cofactor HCF-1 and associated hSet1/MLL histone H3 lysine 4 methyltransferase complex, facilitating the activation of genes required for proliferation.
openaire +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu +8 more
wiley +1 more source
BMC Cancer, 2012 Background Overexpression of the human epidermal growth factor receptor (HER) 2 is associated with poor prognosis and shortened survival in breast cancer patients.
Tina Elisabet +5 more
doaj +1 more source
Phase composition and thermoelectric properties of the nanocomposite alloys NaxCu2-x-y S
Eurasian Journal of Physics and Functional Materials, 2021 Nanocrystalline alloys of the compositions Na 0.05 Cu 1.95 S, Na 0.075 Cu 1.925 S, Na 0.10 Cu 1.90 S, Na 0.125 Cu 1.750 S, Na 0.15 Cu 1.85 S, Na 0.17 Cu 1.80 S, Na 0.20 Cu 1.77 S were synthesized in a melt medium mixtures of hydroxides NaOH and KOH at a ...
M. M. Kubenova +5 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman +7 more
wiley +1 more source
Cell size at S phase initiation: an emergent property of the G1/S network. [PDF]
PLoS Computational Biology, 2007 The eukaryotic cell cycle is the repeated sequence of events that enable the division of a cell into two daughter cells. It is divided into four phases: G1, S, G2, and M.
Matteo Barberis +3 more
doaj +1 more source
Developing S-phase control [PDF]
Genes & Development, 2012 The duration of S phase in early embryos is often short, and then increases as development proceeds because of the appearance of late-replicating regions of the genome. In the April 1, 2012, issue of Genes & Development, Farrell and colleagues (pp.
openaire +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Osteosarcoma (OS) and Ewing sarcoma (EWS) are the most common primary bone cancers in children, but acute thrombosis is poorly characterized in this population. Our study evaluated the rates of venous thromboembolism (VTE) and associated risk factors in pediatric patients with bone sarcomas treated over a 10‐year period encompassing
Sarah Kappa +8 more
wiley +1 more source
ROBUSTIFICATION OF MULTIVARIATE CONTROL CHART √|S| IN CONTROL PHASE I
Revista de la Facultad de Ciencias, 2016 This article, chart robustification based on the square root of the sample generalized variance √|S|, is studied to control the variability of a bivariate normal process in stage 1 of Phase I control, built with observations for rational subgroups, and ...
Edwin Dugarte-Peña +1 more
doaj +1 more source