Results 141 to 150 of about 274,580 (343)

Mixed membership analysis of high-throughput interaction studies: Relational data [PDF]

open access: yesarXiv, 2007
In this paper, we consider the statistical analysis of a protein interaction network. We propose a Bayesian model that uses a hierarchy of probabilistic assumptions about the way proteins interact with one another in order to: (i) identify the number of non-observable functional modules; (ii) estimate the degree of membership of proteins to modules ...
arxiv  

PAS10 is a tetratricopeptide-repeat protein that is essential for the import of most matrix proteins into peroxisomes of Saccharomyces cerevisiae.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 1993
pas mutants of Saccharomyces cerevisiae are disturbed in peroxisome assembly (pas) and proliferation. Here we report the characterization of the PAS10 gene and its product (PAS10) that is essential for the import of a large subset of proteins into the ...
Inge N. A. Van   +5 more
semanticscholar   +1 more source

Designing Enzymatic Reactivity with an Expanded Palette

open access: yesChemBioChem, EarlyView.
Innovation in biocatalysis is rapidly increasingly the diversity of catalytic reactivity that can be mediated by enzymes, addressing a key bottleneck for their widespread adoption in industrial chemical synthesis. A key approach to this is building enzymes with unnatural catalytic components that provide an expanded palette with new possibilities for ...
Reuben B. Leveson‐Gower
wiley   +1 more source

Saccharomyces cerevisiae kinesin- and dynein-related proteins required for anaphase chromosome segregation

open access: yesJournal of Cell Biology, 1995
The Saccharomyces cerevisiae kinesin-related gene products Cin8p and Kip1p function to assemble the bipolar mitotic spindle. The cytoplasmic dynein heavy chain homologue Dyn1p (also known as Dhc1p) participates in proper cellular positioning of the ...
William S. Saunders   +7 more
semanticscholar   +1 more source

Identification of key active site positions controlling the chemoselectivity of Aspergillus brasiliensis unspecific peroxygenase

open access: yesChemBioChem, Accepted Article.
Heme‐containing unspecific peroxygenases (UPOs) have catched significant attention as biocatalysts for oxidation reactions due to their ability to function without expensive nicotinamide cofactors. In our recent study, the UPO from Aspergillus brasiliensis (AbrUPO) was found to catalyze the aromatic hydroxylation of substituted benzenes, a feature that
Fabian Schmitz   +8 more
wiley   +1 more source

Understanding and predicting synthetic lethal genetic interactions in Saccharomyces cerevisiae using domain genetic interactions [PDF]

open access: yesarXiv, 2011
Genetic interactions have been widely used to define functional relationships between proteins and pathways. In this study, we demonstrated that yeast synthetic lethal genetic interactions can be explained by the genetic interactions between domains of those proteins.
arxiv  

The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae

open access: yesYeast, 1998
Screening of the complete genome sequence from the yeast Saccharomyces cerevisiae has enabled us to compile a complete list of the genes encoding cytoplasmic ribosomal proteins in this organism.
R. Planta, W. Mager
semanticscholar   +1 more source

Purple and red rice (Oryza sativa L.) bran polyphenols show antiobesity and antidiabetic activities

open access: yesCereal Chemistry, EarlyView.
Abstract Background and Objectives Rice bran is a source of bioactive polyphenols. This study aimed to characterize the antidiabetic potential of different rice brans (one brown, two red, and two purple) by examining their ability to inhibit α‐amylase, α‐glucosidase, and pancreatic lipase, and to stimulate glucose uptake in adipocytes.
Stephen M. Boue   +2 more
wiley   +1 more source

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