Results 51 to 60 of about 262,483 (141)

Swine acute diarrhea syndrome coronavirus-induced apoptosis is caspase- and cyclophilin D- dependent

Emerging Microbes and Infections, 2020
Swine acute diarrhea syndrome coronavirus (SADS-CoV), a newly discovered enteric coronavirus, is the aetiological agent that causes severe clinical diarrhea and intestinal pathological damage in piglets. To understand the effect of SADS-CoV on host cells,
Jiyu Zhang, Yuru Han, Hongyan Shi, Jianfei Chen, Xin Zhang, Xiaobo Wang, Ling Zhou, Jianbo Liu, Jialin Zhang, Zhaoyang Ji, Zhaoyang Jing, Jingyun Ma, Da Shi, Li Feng   +13 more
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Furin cleavage is required for swine acute diarrhea syndrome coronavirus spike protein-mediated cell – cell fusion

Emerging Microbes and Infections, 2022
Swine acute diarrhea syndrome coronavirus (SADS-CoV) was reported in China in 2017 and is a causative agent of porcine enteric disease. Recent studies indicate that cells from various hosts are susceptible to SADS-CoV, suggesting the zoonotic potential ...
Jinman Kim, Jaewon Yoon, Jung-Eun Park
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Metabolomic analysis of porcine intestinal epithelial cells during swine acute diarrhea syndrome coronavirus infection

Frontiers in Cellular and Infection Microbiology, 2022
Swine acute diarrhea syndrome coronavirus (SADS-CoV) is an enveloped, positive single-stranded RNA virus belonging to Coronaviridae family, Orthocoronavirinae subfamily, Alphacoronavirus genus.
Siying Zeng, Ouyang Peng, Fangyu Hu, Yu Xia, Rui Geng, Yan Zhao, Yihong He, Qiuping Xu, Chunyi Xue, Yongchang Cao, Hao Zhang   +10 more
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Swine acute diarrhea syndrome coronavirus induces autophagy to promote its replication via the Akt/mTOR pathway

iScience, 2022
Summary: Swine acute diarrhea syndrome coronavirus (SADS-CoV) is an enveloped, single-stranded, positive-sense RNA virus belonging to the Coronaviridae family.
Siying Zeng, Yan Zhao, Ouyang Peng, Yu Xia, Qiuping Xu, Hongmei Li, Chunyi Xue, Yongchang Cao, Hao Zhang   +8 more
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The ER stress sensor IRE1, but not PERK-EIF2S1 and ATF6, is involved in SADS-CoV-induced autophagy and facilitates SADS-CoV replication.

, 2023
(A and B) ST cells are treated with the indicated concentrations of salubrinal for 2 h and then infected with SADS-CoV (MOI = 0.1). After the adsorption of viruses to cells, media containing the indicated concentrations of salubrinal is added.
Jianfei Chen (3186999), Zhaoyang Jing (9110860), Haojie He (14761730), Hongyan Shi (1988656), Dakai Liu (10474934), Da Shi (1455439), Jingyun Ma (1885213), Tingshuai Feng (14761721), Li Feng (77923), Ling Zhou (51948), Jiyu Zhang (725001), Xin Zhang (35492), Mei Xue (163742), Jianbo Liu (315277), Jialin Zhang (320005), Zhaoyang Ji (14761727), Longjun Guo (315268), Liaoyuan Zhang (12157704), Miaomiao Zeng (14761724), Yang Wu (66682)   +19 more
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Autolysosome formation in SADS-CoV-infection cells.

, 2023
Vero E6 cells are transfected with plasmid expressing GFP-RFP-LC3 for 12 h, and the cells are infected with SADS-CoV at an MOI of 1. After absorption for 1 h, cells are observed over time by live cell imaging with RFP and GFP channels to produce time ...
Jianfei Chen (3186999), Zhaoyang Jing (9110860), Haojie He (14761730), Hongyan Shi (1988656), Dakai Liu (10474934), Da Shi (1455439), Jingyun Ma (1885213), Tingshuai Feng (14761721), Li Feng (77923), Ling Zhou (51948), Jiyu Zhang (725001), Xin Zhang (35492), Mei Xue (163742), Jianbo Liu (315277), Jialin Zhang (320005), Zhaoyang Ji (14761727), Longjun Guo (315268), Liaoyuan Zhang (12157704), Miaomiao Zeng (14761724), Yang Wu (66682)   +19 more
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The Characteristics of Spike Glycoprotein Gene of Swine Acute Diarrhea Syndrome Coronavirus Strain CH/FJWT/2018 Isolated in China

Frontiers in Veterinary Science, 2021
Swine acute diarrhea syndrome (SADS) is a highly contagious infectious disease characterized by acute vomiting and watery diarrhea in neonatal piglets.
Yan-Yan Guo, Pei-Hua Wang, Yuan-Qing Pan, Rui-Zhu Shi, Ya-Qian Li, Fan Guo, Li Xing, Li Xing, Li Xing   +8 more
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SADS-CoV PLP2-TM activates all three UPR signaling pathways and interaction with GRP78 protein.

, 2023
(A and B) Vero E6 and ST cells are transfected with increasing doses of pCAGGS-HA-PLP2-TM. At 36 hpi, western blotting is performed using the indicated antibodies (left panel).
Jianfei Chen (3186999), Zhaoyang Jing (9110860), Haojie He (14761730), Hongyan Shi (1988656), Dakai Liu (10474934), Da Shi (1455439), Jingyun Ma (1885213), Tingshuai Feng (14761721), Li Feng (77923), Ling Zhou (51948), Jiyu Zhang (725001), Xin Zhang (35492), Mei Xue (163742), Jianbo Liu (315277), Jialin Zhang (320005), Zhaoyang Ji (14761727), Longjun Guo (315268), Liaoyuan Zhang (12157704), Miaomiao Zeng (14761724), Yang Wu (66682)   +19 more
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Swine acute diarrhea syndrome coronavirus (SADS-CoV) [PDF]

, 2021
Swine acute diarrhea syndrome coronavirus (SADS-CoV), a newly emerging enteric coronavirus in China, is associated with swine acute diarrhea syndrome (SADS), which has caused significant economic losses to the porcine industry.
Gliński, Zdzisław, Żmuda, Andrzej
core  

Porcine intestinal enteroid (PIE) cultures support SADS-CoV replication.

, 2022
(A) Ileal PIE monolayers were incubated with medium or SADS-CoV-GFP at the indicated MOIs on a rotary shaker for 1 h at 37°C. The incubated monolayers were washed three times with PBS and harvested at 1 or 48 hpi.
Chan Ding (317445), Yao-Wei Huang (426136), Shu Jeffrey Zhu (12867687), Yi-Xin Tang (12867684), Pan Qin (6517490), Qi-Yue Yang (12867681), Shu-Xian Chen (10719084), Jin-Yan Xie (9920614), Yong-Le Yang (10977618), Gan Wang (786657)   +9 more
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